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Refrigerants and blowing agents

1,1-Difluoroethane

Also known as Ethylidene fluoride, Ethylidene difluoride, Ethane, 1,1-difluoro-

CAS 75-37-6Formula C2H4F2Molar mass 66.05 g/molEC 200-866-1
GHS signal word: Danger. Pictograms: Flammable, Gas under pressure 13 suppliers listed
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1,1-Difluoroethane chemical structure, C2H4F2, CAS 75-37-6
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Colorless gas
Melting point
-118.6 °C
Boiling point
-24.1 °C
Density
Density (for liquid): 0.91 g/cm³
Flash point
<-50
HS code
290343
Category
Refrigerants and blowing agents
UN number
UN 1030
Illustrative photo, a small gas cylinder with a regulator in a lab on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is 1,1-Difluoroethane?

Plain description, key identifiers and synonyms

1,1-Difluoroethane is colorless, odorless gas shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air and a flame can travel back to the source of leak very easily. This leak can be either a liquid or vapor leak. It can asphyxiate by the displacement of air. Under prolonged exposure to fire or heat the containers may rupture violently and rocket.

1,1-Difluoroethane is an organofluorine compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1,1-difluoroethane
CAS number
75-37-6 CAS number cross-checkedOther or deprecated CAS: 25497-28-3
EC numbers
200-866-1, 687-441-8
Molecular formula
C2H4F2
UNII
0B1U8K2ME0
MDL number
MFCD00000449
INCI name
HYDROFLUOROCARBON 152A
InChIKey
NPNPZTNLOVBDOC-UHFFFAOYSA-N
InChI
InChI=1S/C2H4F2/c1-2(3)4/h2H,1H3
SMILES (canonical and isomeric)
CC(F)F

Synonyms

  • Ethylidene fluoride
  • Ethylidene difluoride
  • Ethane, 1,1-difluoro-
  • HFC-152a
  • Genetron 152a
  • Algofrene type 67
  • Freon 152a
  • Propellant 152a
  • Halocarbon 152A
  • Refrigerant 152a
  • Genetron 100
  • Ethylene fluoride
  • Dymel 152A
  • Dymel 152
  • Hydrofluorocarbon 152a
  • HFC 152a
  • Fluorocarbon 152a
  • R 152a
  • FC 152a
  • R-152a
  • Difluoroethane
  • 1, 1-Difluoroethane
  • 1,1-Difluoro-ethane
  • Norflurane EP Impurity E
  • R152a
Show all 29 synonyms
  • 1,1-Difluoroethane, >=98%
  • 1,1-Difluoroethane (FC-152a)
  • UN 1030
  • 1,1-Difluoroethane 10% (wt/wt) in N,N-Dimethylacetamide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless gasexp.
Odour
Odorlessexp.
Melting point
-118.6 °Cexp.
Boiling point
-24.1 °Cexp.
Density
Density (for liquid): 0.91 g/cm³exp.
Flash point
<-50exp.
Autoignition temperature
455 °Cexp.
Solubility
In water, 3.2 × 10⁺³ mg/L at 25 °Cexp.
Vapour pressure
0.750 mm Hg at -115.2 °C, 7.50 mm Hg at -94.6 °C, 75.0 mm Hg at -66.1 °C, 750 mm Hg at -24.3 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
66.05 g/molcalc.
Exact mass
66.0281 Dacalc.
LogP (octanol/water)
1.27calc.
Topological polar surface area
0 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
0calc.
Rotatable bonds
0calc.
Heavy atoms
4calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS02: Flammable
Flammable
GHS04: Gas under pressure
Gas under pressure

Hazard statements

  • H220Extremely flammable gas.
  • H280Contains gas under pressure, may explode if heated.
Precautionary statements (8)
  • P203Obtain, read and follow all safety instructions before use.
  • P210Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking.
  • P222Do not allow contact with air.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P377Leaking gas fire: do not extinguish, unless leak can be stopped safely.
  • P381In case of leakage, eliminate all ignition sources.
  • P403Store in a well-ventilated place.
  • P410 + P403Protect from sunlight. Store in a well-ventilated place.
UN number
UN 1030
Transport hazard class
2.1

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

1,1-Difluoroethane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 13 suppliers
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Where suppliers are based

13 suppliers in 3 countries

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1,1-Difluoroethane price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

1,1-Difluoroethane is employed for aerosol pesticide formulations used for insect control in food and feed-handling establishments and animals. The predominant use of this chemical is in consumer products, including use as an aerosol propellant in food and non-food commodities, as refrigerant, and in the synthesis of 1-chloro-1,1-difluoroethane.

Intermediate.

Intermediate to vinyl fluoride.

HFC 152a is a specialty liquified hydrofluorocarbon gas. It is used as an intermediate in the production of fluorinated polymers, as an aerosol propellant in some specialty applications, and as a component in some refrigerant blends.

Approximately 80% of HFC-152a is used as an aerosol propellant and approximately 15% is used as a foam expansion agent.

Read more

The remaining 5% of the HFC-152a is for other potential uses, which include refrigeration blends and catalyst regeneration.

Industrial uses: Foamant, Energy Releasers (explosives, motive propellant), Refrigerants, Dusting agent, Propellants, non-motive (blowing agents), Intermediate.

Consumer uses: Dusting agent, Cleaning agent, Refrigerants, Propellants, non-motive (blowing agents), Foamant, Energy Releasers (explosives, motive propellant).

Use classes: Cosmetics.

Cosmetic ingredient, INCI name HYDROFLUOROCARBON 152A(propellant)

Functional uses

  • Foamant
  • Propellants, non-motive (blowing agents)

Cosmetic functions

  • Propellant

How it is made

Mono- and difluoroalkanes can be produced by addition of hydrogen fluoride to olefins or alkynes (e.g., CF2H-CH3, HFC 152a). Another synthetic pathway is the exchange of chlorine (or bromine) for fluorine using hydrogen fluoride or metal fluorides, such as antimony fluoride.

By adding hydrogen fluoride to acetylene.

Gas-phase fluorination of acetylene using a magnesium and bismuth catalyst coadsorbed on aluminum fluoride (Mg/Bi/AlF3). This method proceeds via the intermediate product, vinyl fluoride.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 1,1-Difluoroethane is traded under.

HS 2903.43Exact HS code

Fluoromethane (HFC-41), 1,2-difluoroethane (HFC-152) and 1,1-difluoroethane (HFC-152a)

World exports in 2024
$160M
+13.5% vs 2023, imports $135M
2022 to 2024
Top exporters
  1. China59.4%
  2. United States22.4%
  3. South Korea7.4%
Top importers
  1. United States34.3%
  2. China9.0%
  3. South Korea8.7%
Reported customs values in USD, not prices.Full trade data

The HS code shown for 1,1-Difluoroethane is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 1,1-Difluoroethane, based on the data on this page

What is 1,1-Difluoroethane?

1,1-Difluoroethane is colorless, odorless gas shipped as a liquefied gas under its vapor pressure. Contact with the liquid can cause frostbite. It is easily ignited. Its vapors are heavier than air and a flame can travel back to the source of leak very easily. This leak can be either a liquid or vapor leak.

What is the CAS number of 1,1-Difluoroethane?

The CAS registry number of 1,1-Difluoroethane is 75-37-6. Other or deprecated CAS numbers: 25497-28-3.

What is the molecular formula and weight of 1,1-Difluoroethane?

The molecular formula of 1,1-Difluoroethane is C2H4F2 and its molar mass is 66.05 g/mol.

What is 1,1-Difluoroethane used for?

1,1-Difluoroethane is employed for aerosol pesticide formulations used for insect control in food and feed-handling establishments and animals.

Is 1,1-Difluoroethane hazardous?

1,1-Difluoroethane carries the GHS signal word "Danger". Main hazards: extremely flammable gas, contains gas under pressure, may explode if heated. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 1,1-Difluoroethane?

1,1-Difluoroethane is usually classified under HS code 290343 (Fluoromethane (HFC-41), 1,2-difluoroethane (HFC-152) and 1,1-difluoroethane (HFC-152a)). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 1,1-Difluoroethane?

CompoundList lists 13 suppliers of 1,1-Difluoroethane in United States, China and Japan. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of 1,1-Difluoroethane?

Suppliers quote 1,1-Difluoroethane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 1,1-Difluoroethane

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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