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Impurities and reference standards

2-Acetamidophenol

Also known as N-(2-Hydroxyphenyl)acetamide, o-Hydroxyacetanilide, 2-Hydroxyacetanilide

CAS 614-80-2Formula C8H9NO2Molar mass 151.17 g/molEC 210-396-9
GHS signal word: Warning. Pictograms: Harmful or irritant 16 suppliers listed
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2-Acetamidophenol chemical structure, C8H9NO2, CAS 614-80-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
614-80-2
Formula
C8H9NO2
Molar mass
151.17 g/mol
EC number
210-396-9
HS code
292429
Category
Impurities and reference standards

What is 2-Acetamidophenol?

Plain description, key identifiers and synonyms

2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties. It has a role as an antineoplastic agent, an antirheumatic drug, a platelet aggregation inhibitor, an anti-inflammatory agent, an apoptosis inducer and a xenobiotic metabolite. It is a member of acetamides and a member of phenols.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-(2-hydroxyphenyl)acetamide
CAS number
614-80-2 CAS number cross-checkedOther or deprecated CAS: 4746-61-6, 57047-65-1
EC number
210-396-9
Molecular formula
C8H9NO2
UNII
4AS8989RNI
MDL number
MFCD00002181
InChIKey
ADVGKWPZRIDURE-UHFFFAOYSA-N
InChI
InChI=1S/C8H9NO2/c1-6(10)9-7-4-2-3-5-8(7)11/h2-5,11H,1H3,(H,9,10)
SMILES (canonical and isomeric)
CC(=O)NC1=CC=CC=C1O

Synonyms

  • N-(2-Hydroxyphenyl)acetamide
  • o-Hydroxyacetanilide
  • 2-Hydroxyacetanilide
  • 2-Acetaminophenol
  • o-Acetamidophenol
  • 2-(Acetylamino)phenol
  • o-(Acetylamino)phenol
  • o-Acetaminophenol
  • N-Acetyl-o-aminophenol
  • N-Acetyl-2-aminophenol
  • Acet-o-aminofenol
  • Acetanilide, 2'-hydroxy-
  • o-Acetylaminofenol
  • 2-(N-Acetylamino)phenol
  • 2'-Hydroxyacetanilide
  • Acetamide, N-(2-hydroxyphenyl)-
  • Phenol, 2-acetamido-
  • Paracetamol EP Impurity A
  • Orthocetamol
  • 2-Hydroxyanilid kyseliny octove
  • N-(2-hydroxyphenyl)ethanamide
  • N-(2-Hydroxyphenyl)acetamide #
  • Paracetamol impurity a
  • Acetylaminophenol
  • N-Phenylglycolamide
Show all 34 synonyms
  • ar-Hydroxyacetanilide
  • Glycolic acid anilide
  • N-(2-Hydroxyphenyl)acetamide (2-Acetamidophenol)
  • 2-acetamido-phenol
  • 2-Acetamidophenol, 97%
  • 2-(N-acetylamino)-phenol
  • 2-Acetamidophenol (Standard)
  • 3-13-00-00778 (Beilstein Handbook Reference)
  • Hydroxyacetanilide, o-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
151.17 g/molcalc.
Exact mass
151.0633 Dacalc.
LogP (octanol/water)
1.35calc.
Topological polar surface area
49.33 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
1calc.
Heavy atoms
11calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

2-Acetamidophenol suppliers

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All 16 suppliers
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Where suppliers are based

16 suppliers in 9 countries

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2-Acetamidophenol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • anti-inflammatory agent
  • antineoplastic agent
  • antirheumatic drug
  • apoptosis inducer
  • hematologic agent
  • metabolite
  • pharmaceutical
  • platelet aggregation inhibitor
  • xenobiotic metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code 2-Acetamidophenol is traded under.

HS 2924.29Indicative HS code

Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other

World exports in 2024
$5.69B
−5.1% vs 2023, imports $5.8B
2019 to 2024
Top exporters
  1. China32.3%
  2. Switzerland * partner reported13.6%
  3. Norway * partner reported12.8%
Top importers
  1. United States15.9%
  2. Ireland15.8%
  3. Germany11.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for 2-Acetamidophenol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about 2-Acetamidophenol, based on the data on this page

What is 2-Acetamidophenol?

2-acetamidophenol is a member of the class of phenols that is 2-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group. A positional isomer of paracetamol which possesses anti-inflammatory, anti-arthritic and anti-platelet aggregation properties.

What is the CAS number of 2-Acetamidophenol?

The CAS registry number of 2-Acetamidophenol is 614-80-2. Other or deprecated CAS numbers: 4746-61-6, 57047-65-1.

What is the molecular formula and weight of 2-Acetamidophenol?

The molecular formula of 2-Acetamidophenol is C8H9NO2 and its molar mass is 151.17 g/mol.

What is 2-Acetamidophenol used for?

Known uses and roles of 2-Acetamidophenol include anti-inflammatories in pharmaceuticals, anti-inflammatory agent, antineoplastic agent, antirheumatic drug, apoptosis inducer and 5 more.

Is 2-Acetamidophenol hazardous?

2-Acetamidophenol carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of 2-Acetamidophenol?

2-Acetamidophenol is usually classified under HS code 292429 (Cyclic amides (including cyclic carbamates) and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy 2-Acetamidophenol?

CompoundList lists 16 suppliers of 2-Acetamidophenol in China, Canada, Germany, India and 5 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy 2-Acetamidophenol in India?

2 suppliers in India list 2-Acetamidophenol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of 2-Acetamidophenol?

Suppliers quote 2-Acetamidophenol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle 2-Acetamidophenol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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