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Heterocyclic building blocks

Aceglatone

Also known as Glucaron, Aceglatona, Aceglatonum

CAS 642-83-1Formula C10H10O8Molar mass 258.18 g/mol
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Aceglatone chemical structure, C10H10O8, CAS 642-83-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
642-83-1
Formula
C10H10O8
Molar mass
258.18 g/mol
HS code
293220
Category
Heterocyclic building blocks

What is Aceglatone?

Plain description, key identifiers and synonyms

Aceglatone is an organic molecular entity.

Aceglatone is an antineoplastic drug available in Japan.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(3R,3aS,6S,6aS)-6-acetyloxy-2,5-dioxo-3,3a,6,6a-tetrahydrofuro[3,2-b]furan-3-yl] acetate
CAS number
642-83-1 CAS number cross-checked
Molecular formula
C10H10O8
UNII
347Q3OOJ13
InChIKey
ZOZKYEHVNDEUCO-DKXJUACHSA-N
InChI
InChI=1S/C10H10O8/c1-3(11)15-7-5-6(18-9(7)13)8(10(14)17-5)16-4(2)12/h5-8H,1-2H3/t5-,6-,7-,8+/m0/s1
Canonical SMILES
CC(=O)OC1C(=O)OC2C(OC(C)=O)C(=O)OC12
Isomeric SMILES
CC(=O)O[C@@H]1[C@@H]2[C@@H]([C@@H](C(=O)O2)OC(=O)C)OC1=O

Synonyms

  • Glucaron
  • Aceglatona
  • Aceglatonum
  • D-Glucaric acid 1,4:6,3-dilactone diacetate
  • 2,5-Di-O-acetyl-D-glucaro-1,4:6,3-dilactone
  • 2,5-Di-O-acetyl-D-glucosaccharo-1,4:6,3-dilactone
  • D-Glucaric acid di-gamma-lactone diacetate
  • 2,5-di-O-acetyl glucaro-(1,4)-(6-3)-dilactone
  • diacetyl glucaro-(1,4)-(6-3)-dilactone
  • GlyTouCan:G56543CB
  • [(3R,3aS,6S,6aS)-6-acetyloxy-2,5-dioxo-3,3a,6,6a-tetrahydrofuro[3,2-b]furan-3-yl] acetate
  • (3R,3aS,6S,6aS)-2,5-dioxohexahydrofuro[3,2-b]furan-3,6-diyl diacetate
  • Aceglaton
  • Glucaron (TN)
  • Aceglatone (JAN/INN)
  • Glucaric acid, 1,4:6,3-dilactone, diacetate, D-
  • [(3R,3aR,6S,6aR)-6-acetyloxy-2,5-dioxo-3,3a,6,6a-tetrahydrofuro[3,2-b]furan-3-yl] acetate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
258.18 g/molcalc.
Exact mass
258.0376 Dacalc.
LogP (octanol/water)
-1.3calc.
Topological polar surface area
105.2 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
2calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.6calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CC2OC(=O)CC2O1

O=C1CC2OC(=O)CC2O1

2 rings, 10 atoms, the Tetrahydrofuro[3,2-b]furan-2,5-dione ring system.

4 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Aceglatone suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 2 suppliers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

2 suppliers in 2 countries

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Aceglatone price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Pharmacology

Aceglatone is a derivative of D-glucaro-1, 4-lactone with chemopreventive and anti-tumor activities. One of the key processes in which human body eliminates toxic chemicals as well as hormones (such as estrogen) is by glucuronidation. When beta-glucuronidase deconjugates these glucuronides, it prolongs the stay of the hormone or toxic chemical in the body. Elevated beta-glucuronidase activity has been implicated to be associated with an increased risk for hormone-dependent cancers like breast, prostate, and colon cancers. Thereby, aceglatone may suppress the developments of hormone-dependent cancers mediated through beta-glucuronidase inhibition.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Aceglatone is traded under.

HS 2932.20Indicative HS code

Lactones

World exports in 2024
$1.97B
−4.7% vs 2023, imports $2.07B
2019 to 2024
Top exporters
  1. China56.3%
  2. India * partner reported7.4%
  3. Germany7.3%
Top importers
  1. United States14.2%
  2. India * partner reported13.5%
  3. Brazil8.5%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Aceglatone is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Aceglatone, based on the data on this page

What is Aceglatone?

Aceglatone is an organic molecular entity.

What is the CAS number of Aceglatone?

The CAS registry number of Aceglatone is 642-83-1.

What is the molecular formula and weight of Aceglatone?

The molecular formula of Aceglatone is C10H10O8 and its molar mass is 258.18 g/mol.

What is Aceglatone used for?

Known uses and roles of Aceglatone include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Aceglatone hazardous?

No GHS hazard classification for Aceglatone is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Aceglatone?

Aceglatone is usually classified under HS code 293220 (Lactones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Aceglatone?

CompoundList lists 2 suppliers of Aceglatone in Japan and South Korea. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Aceglatone?

Suppliers quote Aceglatone on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Aceglatone

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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