Amcinonide
Also known as Cyclocort, Amcinonidum, Visderm
Key facts
What buyers check first
- CAS number
- 51022-69-6
- Formula
- C28H35FO7
- Molar mass
- 502.58 g/mol
- EC number
- 256-915-2
- HS code
- 293722
- Category
- Hormones and steroids
What is Amcinonide?
Plain description, key identifiers and synonyms
Amcinonide is an 11beta-hydroxy steroid, a 20-oxo steroid, an acetate ester, a fluorinated steroid, a corticosteroid, a spiroketal and a 3-oxo-Delta(1),Delta(4)-steroid. It has a role as an anti-inflammatory drug. It derives from a hydride of a pregnane.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- [2-[(1S,2S,4R,8S,9S,11S,12R,13S)-12-fluoro-11-hydroxy-9,13-dimethyl-16-oxospiro[5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-diene-6,1'-cyclopentane]-8-yl]-2-oxoethyl] acetate
- CAS number
- 51022-69-6 CAS number cross-checked
- EC number
- 256-915-2
- Molecular formula
- C28H35FO7
- UNII
- 423W026MA9
- MDL number
- MFCD00213379
- InChIKey
- ILKJAFIWWBXGDU-MOGDOJJUSA-N
- InChI
- InChI=1S/C28H35FO7/c1-16(30)34-15-22(33)28-23(35-26(36-28)9-4-5-10-26)13-20-19-7-6-17-12-18(31)8-11-24(17,2)27(19,29)21(32)14-25(20,28)3/h8,11-12,19-21,23,32H,4-7,9-10,13-15H2,1-3H3/t19-,20-,21-,23+,24-,25-,27-,28+/m0/s1
- Canonical SMILES
- CC(=O)OCC(=O)C12OC3(CCCC3)OC1CC1C3CCC4=CC(=O)C=CC4(C)C3(F)C(O)CC12C
- Isomeric SMILES
- CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CCC5=CC(=O)C=C[C@@]54C)F)O)C)OC6(O2)CCCC6
Synonyms
- Cyclocort
- Amcinonidum
- Visderm
- amcinonida
- Triamcinolonacetatcyclopentanonid
- CL 34699
- 1,4-Pregnadiene-2,20-dione-16,17-cyclopentylidenedioxy-9-fluoro-11,21-dihydroxy-21-acetate
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-(cyclopentylidenebis(oxy))-9-fluoro-11-hydroxy-, (11beta,16alpha)-
- triamcinolone 16,17-cyclopentylidenedioxy-21-acetate
- 9-Fluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with cyclopentanone, 21-acetate
- Amcinonido
- Cyclocort (TN)
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-[cyclopentylidenebis(oxy)]-9-fluoro-11-hydroxy-, (11beta,16alpha)-
- Amcinonide (JAN/USP/INN)
- Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-16,17-(cyclopentylidenebis(oxy))-9-fluoro-11-hydroxy-, (11beta,16.alpha.)-
- Amcinonide (Standard)
- 19alpha-Fluor-11beta,21-dihydroxy-16alpha,17alpha-(tetramethylen)methylendioxy-1,4-pregnadien-3,20-dion 21-acetat
- Amcinonide, analytical standard
- 16alpha,17alpha-(cyclopentane-1,1-diyldioxy)-9-fluoro-11beta-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate
- Amcinonide Solution in Acetonitrile, 100ug/mL
- Amcinonide Solution in Acetonitrile, 1000ug/mL
- Amcinonide, United States Pharmacopeia (USP) Reference Standard
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 502.58 g/molcalc.Computed value |
|---|---|
| Exact mass | 502.2367 Dacalc.Computed value |
| LogP (octanol/water) | 3.52calc.Computed value |
| Topological polar surface area | 99.13 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 7calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 36calc.Computed value |
| Rings | 6calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.75calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 8calc.Computed value |
| Lipinski rule of five | Passes (1 violation)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H361Suspected of damaging fertility or the unborn child.
- H373May cause damage to organs through prolonged or repeated exposure.
Precautionary statements (7)
- P203Obtain, read and follow all safety instructions before use.
- P260Do not breathe dust, fume, gas, mist, vapours or spray.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P318If exposed or concerned, get medical advice.
- P319Get medical help if you feel unwell.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidAmcinonide suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Germany, HamminkelnUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
- China, Tai'an ManufacturerUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
- Italy, Gropello Cairoli ManufacturerUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
- Israel, Haifa Bay ManufacturerUnclaimed profileAmcinonideGrade Pharma (USP)Price on request
- ItalyUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
- Netherlands, OldenzaalUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
- Mexico, Lerma ManufacturerUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
- Price on request
- Price on request
- India ManufacturerUnclaimed profileAmcinonideGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
20 suppliers in 9 countries
- China5
- United States5
- India2
- Italy2
- Australia1
- Germany1
- and 3 more countries
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Amcinonide price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Glucocorticoids
Roles
- anti-inflammatory agent
- anti-inflammatory drug
- pharmaceutical
Pharmacology
Amcinonide is a Corticosteroid. The mechanism of action of amcinonide is as a Corticosteroid Hormone Receptor Agonist.
Regulatory status
Inventories, regulations and trade controls that list this substance
Health and food
- Active ingredient in FDA approved drug labels
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Amcinonide is traded under.
Halogenated derivatives of corticosteroidal hormones
- United Kingdom69.1%
- Italy7.8%
- Singapore5.6%
- United States64.5%
- Spain5.1%
- United Kingdom3.7%
The HS code shown for Amcinonide is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Amcinonide, based on the data on this page
What is Amcinonide?
What is the CAS number of Amcinonide?
What is the molecular formula and weight of Amcinonide?
What is Amcinonide used for?
Is Amcinonide hazardous?
What is the HS code of Amcinonide?
Where can I buy Amcinonide?
Where can I buy Amcinonide in India?
What is the price of Amcinonide?
Guides for buyers
Practical guides that help when you source, ship or handle Amcinonide
- Article, QualityPharma grades explained: IP vs BP vs USP vs EPWhat the Indian, British, US and European pharmacopoeias are, how their monographs differ, what multi grade claims mean and why a grade alone does not make a product fit for medicines.Read
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
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