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Hormones and steroids

Fluocinonide

Also known as Fluocinolide, Lidex, Vanos

CAS 356-12-7Formula C26H32F2O7Molar mass 494.53 g/molEC 206-597-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 54 suppliers listed Drug substance
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Fluocinonide chemical structure, C26H32F2O7, CAS 356-12-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
356-12-7
Formula
C26H32F2O7
Molar mass
494.53 g/mol
EC number
206-597-6
HS code
293722
Category
Hormones and steroids

What is Fluocinonide?

Plain description, key identifiers and synonyms

Fluocinonide is an organic molecular entity.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[2-[(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-6,6,9,13-tetramethyl-16-oxo-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-8-yl]-2-oxoethyl] acetate
CAS number
356-12-7 CAS number cross-checked
EC number
206-597-6
Molecular formula
C26H32F2O7
UNII
2W4A77YPAN
MDL number
MFCD00079302
InChIKey
WJOHZNCJWYWUJD-IUGZLZTKSA-N
InChI
InChI=1S/C26H32F2O7/c1-13(29)33-12-20(32)26-21(34-22(2,3)35-26)10-15-16-9-18(27)17-8-14(30)6-7-23(17,4)25(16,28)19(31)11-24(15,26)5/h6-8,15-16,18-19,21,31H,9-12H2,1-5H3/t15-,16-,18-,19-,21+,23-,24-,25-,26+/m0/s1
Canonical SMILES
CC(=O)OCC(=O)C12OC(C)(C)OC1CC1C3CC(F)C4=CC(=O)C=CC4(C)C3(F)C(O)CC12C
Isomeric SMILES
CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3C[C@@H](C5=CC(=O)C=C[C@@]54C)F)F)O)C)OC(O2)(C)C

Synonyms

  • Fluocinolide
  • Lidex
  • Vanos
  • LIDEX-E
  • Fluocinonide Emulsified Base
  • Fluocinonidum
  • Fluocinolone acetonide 21-acetate
  • Fluocinonida
  • Pregna-1,4-diene-3,20-dione, 21-(acetyloxy)-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))-, (6alpha,11beta,16alpha)-
  • Pregna-1,4-diene-3,20-dione, 6alpha,9-difluoro-11beta,16alpha,17,21-tetrahydroxy-, cyclic 16,17-acetal with acetone, 21-acetate
  • Fluocinonide FAPG
  • Lidemol
  • Tiamol
  • Metosyn fapg
  • Fluocinol Pak
  • Fluovix Plus
  • FAPG, Fluocinonide
  • Fluocinolone Acetonide 21 Acetate
  • Acetonide 21-Acetate, Fluocinolone
  • Fluocinonide Topical Solution USP, 0.05%
  • fluocinonide cream, silicone roll, self-adhesive wrap
  • (6alpha,11beta,16alpha)-21-(Acetyloxy)-6,9-difluoro-11-hydroxy-16,17-((1-methylethylidene)bis(oxy))pregna-1,4-diene-3,20-dione
  • 6alpha,9-Difluoro-11beta,21-dihydroxy-16alpha,17-(1-methylethylidenedioxy)pregna-1,4-diene-3,20-dione 21-acetate
  • Fluocinolone acetonide acetate
  • Fluocinolide acetate
Show all 34 synonyms
  • Fluocinonido
  • Lidex E
  • Fluocinonide(Vanos)
  • 6alpha,9-Difluoro-11beta,16alpha,17,21-tetrahydroxypregna-1,4-diene-3,20-dione, cyclic 16,17-acetal with acetone, 21-acetate
  • Fluonex
  • Fluocinomide
  • Vanos (TN)
  • LIDEX (TN)
  • oethyl acetate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
494.53 g/molcalc.
Exact mass
494.2116 Dacalc.
LogP (octanol/water)
2.94calc.
Topological polar surface area
99.13 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
7calc.
Rotatable bonds
3calc.
Heavy atoms
35calc.
Rings
5calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.73calc.
Formal charge
0calc.
Stereocentres
9calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OCOC12

O=C1C=CC2C(=C1)CCC1C2CCC2C1CC1OCOC12

5 rings, 21 atoms.

180 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H300Fatal if swallowed.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Fluocinonide suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 54 suppliers
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Where suppliers are based

54 suppliers in 12 countries

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Fluocinonide price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Allergic Agents
  • Anti-Inflammatory Agents
  • Glucocorticoids

Pharmacology

Fluocinonide is a Corticosteroid. The mechanism of action of fluocinonide is as a Corticosteroid Hormone Receptor Agonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fluocinonide is traded under.

HS 2937.22Indicative HS code

Halogenated derivatives of corticosteroidal hormones

World exports in 2024
$1.65B
−29.3% vs 2023, imports $1.67B
2019 to 2024
Top exporters
  1. United Kingdom69.1%
  2. Italy7.8%
  3. Singapore5.6%
Top importers
  1. United States64.5%
  2. Spain5.1%
  3. United Kingdom3.7%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Fluocinonide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fluocinonide, based on the data on this page

What is Fluocinonide?

Fluocinonide is an organic molecular entity.

What is the CAS number of Fluocinonide?

The CAS registry number of Fluocinonide is 356-12-7.

What is the molecular formula and weight of Fluocinonide?

The molecular formula of Fluocinonide is C26H32F2O7 and its molar mass is 494.53 g/mol.

What is Fluocinonide used for?

Use classes: Pharmaceuticals.

Is Fluocinonide hazardous?

Fluocinonide carries the GHS signal word "Danger". Main hazards: fatal if swallowed, suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Fluocinonide?

Fluocinonide is usually classified under HS code 293722 (Halogenated derivatives of corticosteroidal hormones). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Fluocinonide?

CompoundList lists 54 suppliers of Fluocinonide in China, United States, India, United Kingdom and 8 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Fluocinonide in India?

3 suppliers in India list Fluocinonide on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Fluocinonide?

Suppliers quote Fluocinonide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Fluocinonide

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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