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Central nervous system drugs

Amisulpride

Also known as Solian, Aminosultopride, Deniban

CAS 71675-85-9Formula C17H27N3O4SMolar mass 369.49 g/molEC 275-831-7
GHS signal word: Warning. Pictograms: Harmful or irritant 163 suppliers listed Drug substance
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Amisulpride chemical structure, C17H27N3O4S, CAS 71675-85-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
71675-85-9
Formula
C17H27N3O4S
Molar mass
369.49 g/mol
EC number
275-831-7
HS code
293399
Category
Central nervous system drugs

What is Amisulpride?

Plain description, key identifiers and synonyms

Amisulpride is a member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist. It is an atypical antipsychotic/antischizophrenic agent with limited extrapyrimidal side effects. It has a role as a xenobiotic, a second generation antipsychotic and an environmental contaminant. It is a member of benzamides, an aromatic amine, a sulfone, a member of pyrrolidines and an aromatic amide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
CAS number
71675-85-9 CAS number cross-checkedOther or deprecated CAS: 53583-79-2
EC number
275-831-7
Molecular formula
C17H27N3O4S
UNII
8110R61I4U
MDL number
MFCD00866691
InChIKey
NTJOBXMMWNYJFB-UHFFFAOYSA-N
InChI
InChI=1S/C17H27N3O4S/c1-4-20-8-6-7-12(20)11-19-17(21)13-9-16(25(22,23)5-2)14(18)10-15(13)24-3/h9-10,12H,4-8,11,18H2,1-3H3,(H,19,21)
SMILES (canonical and isomeric)
CCN1CCCC1CNC(=O)C2=CC(=C(C=C2OC)N)S(=O)(=O)CC

Synonyms

  • Solian
  • Aminosultopride
  • Deniban
  • Amisulprida
  • Amisulpridum
  • Socian
  • Barhemsys
  • 4-Amino-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
  • Sulamid
  • 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
  • 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-o-anisamide
  • 4-Amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
  • 4-amino-5-(ethanesulfonyl)-N-[(1-ethylpyrrolidin-2-yl)methyl]-2-methoxybenzamide
  • Benzamide, 4-amino-N-((1-ethyl-2-pyrrolidinyl)methyl)-5-(ethylsulfonyl)-2-methoxy-
  • 4-amino-5-(ethanesulfonyl)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxybenzamide
  • 4-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-ethylsulfonyl-2-methoxybenzamide
  • Solian 50
  • Solian 100
  • Solian 200
  • Solian 400
  • Amisulpiride
  • DAN 2163
  • Amisulpride free base
  • 4-amino-N-((1-ethylpyrrolidin-2-yl)methyl)-5-(ethylsulfonyl)-2-methoxybenzamide
  • Amisulpride (INN)
Show all 34 synonyms
  • S-Amisulpride
  • R-Amisulpride
  • 4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-2-methoxybenzamide
  • Sulpitac
  • Deniban (TN)
  • Solian (TN)
  • Amisulpride?
  • Aminosultopride,
  • Amisulpride CRS

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
369.49 g/molcalc.
Exact mass
369.1722 Dacalc.
LogP (octanol/water)
1.29calc.
Topological polar surface area
101.7 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
7calc.
Heavy atoms
25calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.59calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NCC1CCCN1)c1ccccc1

O=C(NCC1CCCN1)c1ccccc1

2 rings, 15 atoms, the Benzamide, N-(2-pyrrolidinylmethyl)- ring system.

214 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Amisulpride suppliers

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All 163 suppliers
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Where suppliers are based

163 suppliers in 23 countries

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Amisulpride price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Neuroleptics, Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Antidepressive Agents, Second-Generation
  • Antipsychotic Agents
  • Dopamine Antagonists

Roles

  • antidepressant
  • antiemetic
  • antipsychotic agent
  • anxiolytic drug
  • appetite enhancer
  • appetite regulator
  • central nervous system depressant
  • central nervous system drug
  • environmental contaminant
  • pharmaceutical
  • psychotropic drug
  • second generation antipsychotic
  • tranquilizing drug
  • xenobiotic

Pharmacology

Amisulpride is a Dopamine-2 Receptor Antagonist. The mechanism of action of amisulpride is as a Dopamine D2 Antagonist.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Amisulpride is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Amisulpride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Amisulpride, based on the data on this page

What is Amisulpride?

Amisulpride is a member of the class of benzamides resulting from the formal condensation of the carboxy group of 4-amino-5-(ethylsulfonyl)-2-methoxybenzoic acid with the primary amino group of 2-(aminomethyl)-1-ethylpyrrolidine. It is a potent, selective dopamine D2 and D3 receptor antagonist.

What is the CAS number of Amisulpride?

The CAS registry number of Amisulpride is 71675-85-9. Other or deprecated CAS numbers: 53583-79-2.

What is the molecular formula and weight of Amisulpride?

The molecular formula of Amisulpride is C17H27N3O4S and its molar mass is 369.49 g/mol.

What is Amisulpride used for?

Use classes: Neuroleptics, Pharmaceuticals.

Is Amisulpride hazardous?

Amisulpride carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful in contact with skin, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Amisulpride?

Amisulpride is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Amisulpride?

CompoundList lists 163 suppliers of Amisulpride in China, India, United States, United Kingdom and 19 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Amisulpride in India?

39 suppliers in India list Amisulpride on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Amisulpride?

Suppliers quote Amisulpride on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Amisulpride

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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