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Levosulpiride

Also known as (-)-Sulpiride, Levopraid, Levopride

CAS 23672-07-3Formula C15H23N3O4SMolar mass 341.43 g/molEC 682-417-3
Levosulpiride chemical structure, C15H23N3O4S, CAS 23672-07-3
2D chemical structure

Key facts

What buyers check first

CAS number
23672-07-3
Formula
C15H23N3O4S
Molar mass
341.43 g/mol
EC number
682-417-3
HS code
293590
Category
Screening compounds

What is Levosulpiride?

Plain description, key identifiers and synonyms

(S)-(-)-sulpiride is an optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 M at D2, D3, D4, D1 and D5 receptors respectively). It has a role as an antidepressant, an antipsychotic agent, a dopaminergic antagonist and an antiemetic. It is an enantiomer of a (R)-(+)-sulpiride.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide
CAS number
23672-07-3 CAS number cross-checked
EC number
682-417-3
Molecular formula
C15H23N3O4S
UNII
JTG7R315LK
MDL number
MFCD00055220
InChIKey
BGRJTUBHPOOWDU-NSHDSACASA-N
InChI
InChI=1S/C15H23N3O4S/c1-3-18-8-4-5-11(18)10-17-15(19)13-9-12(23(16,20)21)6-7-14(13)22-2/h6-7,9,11H,3-5,8,10H2,1-2H3,(H,17,19)(H2,16,20,21)/t11-/m0/s1
Canonical SMILES
CCN1CCCC1CNC(=O)c1cc(S(N)(=O)=O)ccc1OC
Isomeric SMILES
CCN1CCC[C@H]1CNC(=O)C2=C(C=CC(=C2)S(=O)(=O)N)OC

Synonyms

  • (-)-Sulpiride
  • Levopraid
  • Levopride
  • L-Sulpiride
  • Levosulpirida
  • Levobren
  • lesuride
  • Levosulpiridum
  • Sulpiride, (s)-
  • Sulpiride, (-)-
  • (-)-N-(((S)-1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • (S)-(-)-N-((1-Ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • S-(-)-N-(1-Ethyl-2-pyrrolidinomethyl)-2-methoxy-5-sulfamoylebenzamide
  • Sulpiride l-
  • N-(((S)-1-ethyl-2-pyrrolidinyl)methyl)-5-sulfamoyl-o-anisamide
  • (S)-(-)-sulpiride
  • S-(-)-Sulpiride
  • (S)-sulpiride
  • N-{[(2S)-1-ethylpyrrolidin-2-yl]methyl}-2-methoxy-5-sulfamoylbenzamide
  • Sulpiride l-form
  • (S)-(-)-5-aminosulfonyl-N-[(1-ethyl-2-pyrrolidinyl)methyl]-2-methoxybenzamide
  • N-[[(2S)-1-ethylpyrrolidin-2-yl]methyl]-2-methoxy-5-sulfamoylbenzamide
  • Benzamide, 5-(aminosulfonyl)-N-[[(2S)-1-ethyl-2-pyrrolidinyl]methyl]-2-methoxy-
  • Levosulpiride (INN)
  • Nexipride
Show all 35 synonyms
  • (S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-methoxy-5-sulfamoylbenzamide
  • Sulpiride,(+)
  • Levogastrol
  • Sulpiride-l
  • Sulpiride-S
  • (S)-N-[(1-Ethylpyrrolidin-2-yl)methyl]-2-methoxy-5-sulfamoylbenzamide
  • Benzamide, 5-(aminosulfonyl)-N-(((2S)-1-ethyl-2-pyrrolidinyl)methyl)-2-methoxy-
  • N-[((2S)-1-ethylpyrrolidin-2-yl)methyl](6-methoxy-3-sulfamoylphenyl)carboxamid e
  • Levopraid (TN)
  • Tocris-0895

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
341.43 g/molcalc.
Exact mass
341.1409 Dacalc.
LogP (octanol/water)
0.56calc.
Topological polar surface area
101.7 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
6calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.53calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NCC1CCCN1)c1ccccc1

O=C(NCC1CCCN1)c1ccccc1

2 rings, 15 atoms, the Benzamide, N-(2-pyrrolidinylmethyl)- ring system.

214 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Levosulpiride suppliers

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Levosulpiride price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • antagonist
  • antidepressant
  • antiemetic
  • antipsychotic agent
  • central nervous system depressant
  • central nervous system drug
  • dopaminergic agent
  • dopaminergic antagonist
  • neurotransmitter agent
  • pharmaceutical
  • psychotropic drug
  • tranquilizing drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Levosulpiride is traded under.

HS 2935.90Indicative HS code

Sulphonamides, other

World exports in 2024
$5.64B
−11.0% vs 2023, imports $8.56B
2019 to 2024
Top exporters
  1. Ireland43.1%
  2. China12.0%
  3. India * partner reported9.5%
Top importers
  1. United States23.6%
  2. Slovenia19.1%
  3. Spain11.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Levosulpiride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Levosulpiride, based on the data on this page

What is Levosulpiride?

(S)-(-)-sulpiride is an optically active form of sulpiride having (S)-configuration. The active enantiomer of the racemic drug sulpiride. Selective D2-like dopamine antagonist (Ki values are ~ 0.015. ~ 0.013, 1, ~ 45 and ~ 77 M at D2, D3, D4, D1 and D5 receptors respectively).

What is the CAS number of Levosulpiride?

The CAS registry number of Levosulpiride is 23672-07-3.

What is the molecular formula and weight of Levosulpiride?

The molecular formula of Levosulpiride is C15H23N3O4S and its molar mass is 341.43 g/mol.

What is Levosulpiride used for?

Known uses and roles of Levosulpiride include building blocks in research and laboratory, screening compounds in research and laboratory, antagonist, antidepressant, antiemetic and 9 more.

Is Levosulpiride hazardous?

No GHS hazard classification for Levosulpiride is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Levosulpiride?

Levosulpiride is usually classified under HS code 293590 (Sulphonamides, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Levosulpiride?

CompoundList lists 53 suppliers of Levosulpiride in India, China, United States, United Kingdom and 4 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Levosulpiride in India?

26 suppliers in India list Levosulpiride on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Levosulpiride?

Suppliers quote Levosulpiride on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Levosulpiride

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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