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Pharmaceuticals and APIs

Apiole

Also known as Apioline, Apiol, Apiole (parsley)

CAS 523-80-8Formula C12H14O4Molar mass 222.24 g/molEC 208-349-2
4 suppliers listed Drug substance
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Apiole chemical structure, C12H14O4, CAS 523-80-8
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
523-80-8
Formula
C12H14O4
Molar mass
222.24 g/mol
EC number
208-349-2
HS code
293299
Category
Pharmaceuticals and APIs

What is Apiole?

Plain description, key identifiers and synonyms

Apiole is a member of benzodioxoles. It has a role as a metabolite.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4,7-dimethoxy-5-prop-2-enyl-1,3-benzodioxole
CAS number
523-80-8 CAS number cross-checked
EC number
208-349-2
Molecular formula
C12H14O4
UNII
QQ67504PXO
MDL number
MFCD00047270
InChIKey
QQRSPHJOOXUALR-UHFFFAOYSA-N
InChI
InChI=1S/C12H14O4/c1-4-5-8-6-9(13-2)11-12(10(8)14-3)16-7-15-11/h4,6H,1,5,7H2,2-3H3
SMILES (canonical and isomeric)
COC1=C2C(=C(C(=C1)CC=C)OC)OCO2

Synonyms

  • Apioline
  • Apiol
  • Apiole (parsley)
  • 5-Allyl-4,7-dimethoxy-1,3-benzodioxole
  • 1-Allyl-2,5-dimethoxy-3,4-methylenedioxybenzene
  • Apiolum
  • 4,7-dimethoxy-5-(prop-2-en-1-yl)-2H-1,3-benzodioxole
  • 4,7-dimethoxy-5-prop-2-enyl-1,3-benzodioxole
  • 4,7-Dimethoxy-5-(2-propen-1-yl)-1,3-Benzodioxole
  • Apiol 1503
  • Parsley apiole
  • Parsley camphor
  • Parsley apiol
  • Petersiliencampher
  • 5-Allyl-4,7-dimethoxybenzo[d][1,3]dioxole
  • 1,3-Benzodioxole, 4,7-dimethoxy-5-(2-propenyl)-
  • 4,7-Dimethoxy-5-(2-propenyl)-1,3-benzodioxole
  • 5-Allyl-4,7-dimethoxy-1,3-benzodioxol
  • 1,3-Benzodioxole, 4,7-dimethoxy-5-(2-propen-1-yl)-
  • Benzene, 1-allyl-2,5-dimethoxy-3,4-(methylenedioxy)-
  • 1-Allyl-2,5-dimethoxy-3,4-(methylenedioxy)benzene
  • 4,7-Dimethoxy-5-(2-propanyl)-1,3-benzodioxole
  • 4,7-dimethoxy-5-prop-2-enyl-2H-benzo[d]1,3-dioxolene
  • Camphre de Persil
  • Apiole, parsley
Show all 32 synonyms
  • 1-Allyl-2,4-(methylenedioxy)benzene
  • 1, 4,7-dimethoxy-5-(2-propenyl)-
  • ApiolineApiole (parsley), Parsley apiole
  • 5-allyl-4,7-dimethoxy-benzo-1,3-dioxole
  • Benzene,5-dimethoxy-3,4-(methylenedioxy)-
  • 5-Allyl-4,7-dimethoxy-1,3-benzodioxole #
  • Apioline, Apiol, Parsley apiole, Parsley camphor

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
222.24 g/molcalc.
Exact mass
222.0892 Dacalc.
LogP (octanol/water)
2.16calc.
Topological polar surface area
36.92 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
16calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc2c(c1)OCO2

c1ccc2c(c1)OCO2

2 rings, 9 atoms, the 1,3-Benzodioxole ring system.

4,560 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Apiole suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers
  • Extrasynthese
    FranceUnclaimed profile
    ApioleGrade, purity and minimum order on request
    Price on request
    View
  • AgroIntelBioScan.com
    Singapore, SingaporeUnclaimed profile
    ApioleGrade, purity and minimum order on request
    Price on request
    View
  • ChemDiv Inc.
    United States, San DiegoUnclaimed profile
    ApioleGrade, purity and minimum order on request
    Price on request
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  • ChemFaces
    China, WuhanUnclaimed profile
    ApioleGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 4 countries

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Apiole price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Roles

  • metabolite

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Apiole is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Apiole is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Apiole, based on the data on this page

What is Apiole?

Apiole is a member of benzodioxoles. It has a role as a metabolite.

What is the CAS number of Apiole?

The CAS registry number of Apiole is 523-80-8.

What is the molecular formula and weight of Apiole?

The molecular formula of Apiole is C12H14O4 and its molar mass is 222.24 g/mol.

What is Apiole used for?

Known uses and roles of Apiole include metabolite.

Is Apiole hazardous?

No GHS hazard classification for Apiole is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Apiole?

Apiole is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Apiole?

CompoundList lists 4 suppliers of Apiole in China, France, Singapore and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Apiole?

Suppliers quote Apiole on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Apiole

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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