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Cosmetic antioxidants

Ethyl ferulate

Also known as Ethyl 4-hydroxy-3-methoxycinnamate, ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate, Ferulic acid, ethyl ester

CAS 4046-02-0Formula C12H14O4Molar mass 222.24 g/molEC 223-745-5
GHS signal word: Warning. Pictograms: Harmful or irritant 17 suppliers listed
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Ethyl ferulate chemical structure, C12H14O4, CAS 4046-02-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
4046-02-0
Formula
C12H14O4
Molar mass
222.24 g/mol
EC number
223-745-5
HS code
291899
Category
Cosmetic antioxidants

What is Ethyl ferulate?

Plain description, key identifiers and synonyms

ethyl ferulate has been reported in Coptis japonica, Solanum nigrum, and other organisms.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
CAS number
4046-02-0 CAS number cross-checkedOther or deprecated CAS: 28028-62-8
EC number
223-745-5
Molecular formula
C12H14O4
UNII
5B8915UELW
INCI name
ETHYL FERULATE
InChIKey
ATJVZXXHKSYELS-FNORWQNLSA-N
InChI
InChI=1S/C12H14O4/c1-3-16-12(14)7-5-9-4-6-10(13)11(8-9)15-2/h4-8,13H,3H2,1-2H3/b7-5+
Canonical SMILES
CCOC(=O)C=Cc1ccc(O)c(OC)c1
Isomeric SMILES
CCOC(=O)/C=C/C1=CC(=C(C=C1)O)OC

Synonyms

  • Ethyl 4-hydroxy-3-methoxycinnamate
  • ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
  • Ferulic acid, ethyl ester
  • Oristract ef
  • Nomcort ef
  • Ethyl 4'-hydroxy-3'-methoxycinnamat
  • 2-Propenoic Acid, 3-(4-Hydroxy-3-Methoxyphenyl)-, Ethyl
  • Ferulic acid ethyl ester
  • Ethyl 4'-hydroxy-3'-methoxycinnamate
  • ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
  • Ethyl (E)-ferulate
  • (E)-Ethyl 3-(4-hydroxy-3-methoxyphenyl)acrylate
  • Ethyl (2e)-3-(4-Hydroxy-3-Methoxyphenyl)prop-2-Enoate
  • Ethyl ferulate - Natural grade
  • 2-Propenoic acid, 3-(4-hydroxy-3-methoxyphenyl)-, ethyl ester, (2E)-
  • ethyl (E)-3-(4-hydroxy-3-methoxy-phenyl)prop-2-enoate
  • Ferulic acid ethylester
  • (E)-3-(4-Hydroxy-3-methoxy-phenyl)-
  • trans-Ferulic acid ethyl ester
  • (E)-3-(4-Hydroxy-3-methoxy-phenyl)-acrylic acid ethyl ester
  • Ferulic acid ethyl ester [M+H]+
  • ethyl (E)-4-hydroxy-3-methoxycinnamate
  • Ethyl trans-4-hydroxy-3-methoxycinnamate
  • Ethyl 4-hydroxy-3-methoxycinnamate, 98%
  • (E)-Ethyl3-(4-hydroxy-3-methoxyphenyl)acrylate
Show all 28 synonyms
  • ethyl (E)-3-(4-hydroxy-3-methoxyphenyl)acrylate
  • Ethyl-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
  • Ethyl (2E)-3-(4-hydroxy-3-methoxyphenyl)-2-propenoate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
222.24 g/molcalc.
Exact mass
222.0892 Dacalc.
LogP (octanol/water)
1.98calc.
Topological polar surface area
55.76 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.25calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ethyl ferulate suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 17 suppliers
17 of 17 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

17 suppliers in 3 countries

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Ethyl ferulate price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name ETHYL FERULATE(antioxidant)

Functional uses

  • Antioxidant
  • Preservative

Cosmetic functions

  • Antioxidant

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ethyl ferulate is traded under.

HS 2918.99Indicative HS code

Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)…

World exports in 2024
$1.46B
−1.1% vs 2023, imports $1.54B
2019 to 2024
Top exporters
  1. China40.0%
  2. India * partner reported26.6%
  3. Germany8.0%
Top importers
  1. United States25.6%
  2. Brazil6.7%
  3. Argentina5.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ethyl ferulate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ethyl ferulate, based on the data on this page

What is Ethyl ferulate?

ethyl ferulate has been reported in Coptis japonica, Solanum nigrum, and other organisms.

What is the CAS number of Ethyl ferulate?

The CAS registry number of Ethyl ferulate is 4046-02-0. Other or deprecated CAS numbers: 28028-62-8.

What is the molecular formula and weight of Ethyl ferulate?

The molecular formula of Ethyl ferulate is C12H14O4 and its molar mass is 222.24 g/mol.

What is Ethyl ferulate used for?

Known uses and roles of Ethyl ferulate include antioxidants in cosmetics and personal care, antioxidant and preservative.

Is Ethyl ferulate hazardous?

Ethyl ferulate carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ethyl ferulate?

Ethyl ferulate is usually classified under HS code 291899 (Carboxylic acids with additional oxygen function and their anhydrides, halides…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ethyl ferulate?

CompoundList lists 17 suppliers of Ethyl ferulate in China, Germany and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ethyl ferulate?

Suppliers quote Ethyl ferulate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ethyl ferulate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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