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Diethyl phthalate

Also known as Ethyl phthalate, phthalic acid diethyl ester, Anozol

CAS 84-66-2Formula C12H14O4Molar mass 222.24 g/molEC 201-550-6
Diethyl phthalate chemical structure, C12H14O4, CAS 84-66-2
2D chemical structure

Key facts

What buyers check first

Appearance
Colorless oily liquid
Melting point
-40.5 °C
Boiling point
295 °C
Density
Relative density (water = 1): 1.1
Flash point
161 °C
HS code
291734
Category
Plasticizers
Illustrative photo, clear liquid in a volumetric flask on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Diethyl phthalate?

Plain description, key identifiers and synonyms

Diethyl phthalate is the diethyl ester of benzene-1,2-dicarboxylic acid. It has a role as a teratogenic agent, a neurotoxin and a plasticiser. It is an ethyl ester, a phthalate ester and a diester.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
diethyl benzene-1,2-dicarboxylate
CAS number
84-66-2 CAS number cross-checked
EC number
201-550-6
Molecular formula
C12H14O4
UNII
UF064M00AF
MDL number
MFCD00009111
INCI name
DIETHYL PHTHALATE
InChIKey
FLKPEMZONWLCSK-UHFFFAOYSA-N
InChI
InChI=1S/C12H14O4/c1-3-15-11(13)9-7-5-6-8-10(9)12(14)16-4-2/h5-8H,3-4H2,1-2H3
SMILES (canonical and isomeric)
CCOC(=O)C1=CC=CC=C1C(=O)OCC

Synonyms

  • Ethyl phthalate
  • phthalic acid diethyl ester
  • Anozol
  • diethyl benzene-1,2-dicarboxylate
  • Neantine
  • Phthalol
  • Solvanol
  • Palatinol A
  • Placidol E
  • Unimoll DA
  • Diethyl o-phthalate
  • Phthalsaeurediaethylester
  • o-Bis(ethoxycarbonyl)benzene
  • Diethyl 1,2-benzenedicarboxylate
  • Estol 1550
  • 1,2-Benzenedicarboxylic acid, diethyl ester
  • Di-n-ethyl phthalate
  • Diethyl o-phenylenediacetate
  • 1,2-Diethyl phthalate
  • Phthalic acid, diethyl ester
  • o-Benzenedicarboxylic acid diethyl ester
  • RCRA waste number U088
  • Diethylester kyseliny ftalove
  • 1,2-benzenedicarboxylic acid diethyl ester
  • 1,2-diethyl benzene-1,2-dicarboxylate
Show all 37 synonyms
  • Diethyl-o-phthalate
  • O-phthalic acid, diethyl ester
  • 1,2-Benzenedicarboxylic acid, 1,2-diethyl ester
  • Diethyl ester of phthalic acid
  • Diethyl ester
  • Diethylphthalate
  • Diclofenac Impurity N
  • Diethyl phthalate (NF)
  • Diethy phthalate
  • Phthalic acid, bis-ethyl ester
  • Diethyl-1,2-benzenedicarboxylate
  • Phthalic acid ethyl ester

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Colorless oily liquidexp.
Odour
Practically odorlessexp.
Taste
Bitter disagreeable tasteexp.
Melting point
-40.5 °Cexp.
Boiling point
295 °Cexp.
Density
Relative density (water = 1): 1.1exp.
Flash point
161 °Cexp.
Autoignition temperature
457 °Cexp.
Solubility
In water, 1,080 mg/L at 25 °Cexp.
Vapour pressure
2.1 × 10⁻³ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
222.24 g/molcalc.
Exact mass
222.0892 Dacalc.
LogP (octanol/water)
2.04calc.
Topological polar surface area
52.6 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
4calc.
Heavy atoms
16calc.
Rings
1calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.33calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccccc1

c1ccccc1

1 ring, 6 atoms, the Benzene ring system.

485,677 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms
110NFPA 704 rating

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Diethyl phthalate suppliers

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All 148 suppliers
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Where suppliers are based

148 suppliers in 23 countries

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Diethyl phthalate price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

In mfr celluloid, solvent for cellulose acetate in mfr varnishes and dopes, denaturing alcohol. Vehicle for fragrance and cosmetic ingredients.

Solvent for nitrocellulose and cellulose acetate, plasticizer, wetting agent, ... camphor substitute, plastics, perfumery as fixative and solvent, alcohol denaturant, ... plasticizer in solid rocket propellants.

Insecticidal sprays ... mosquito repellents (Former).

Plasticizer for cellulose ester plastics, dispersing medium, eg, dye carrier, plasticizer for other plastics, eg, polystyrene.

Industrial uses: Binder, Solvent, Processing aids not otherwise specified, Plasticizer, Fragrance, Adhesion/cohesion promoter.

Consumer uses: Diluent, Fragrance, Plasticizer, Processing aids not otherwise specified, Binder, Insulators.

Use classes: Phthalates, Cosmetics.

Cosmetic ingredient, INCI name DIETHYL PHTHALATE(denaturant, film forming, hair conditioning, fragrance)

Roles

  • aetiopathogenetic role
  • neurotoxin
  • plasticiser
  • poison
  • teratogenic agent

Functional uses

  • Deodorizer
  • Film former
  • Fragrance
  • Lubricating agent
  • Plasticizer
  • Processing aids not otherwise specified
  • Softener and conditioner
  • Solvent
  • Viscosity modifier

Cosmetic functions

  • Denaturant
  • Film forming
  • Fragrance
  • Hair conditioning
  • Plasticiser
  • Solvent

Pharmacology

Diethyl Phthalate is a clear, colorless liquid used as a plasticizer for fabricating flexible materials for many household products. It is also used in cosmetics, insecticides and aspirin.

How it is made

By reacting phthalic anhydride with ethanol followed by careful purification

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Diethyl phthalate is traded under.

HS 2917.34Indicative HS code

Aromatic polycarboxylic acids, other esters of orthophthalic acids

World exports in 2024
$279M
−7.8% vs 2023, imports $292M
2019 to 2024
Top exporters
  1. China18.7%
  2. India * partner reported16.0%
  3. South Korea14.2%
Top importers
  1. United States10.6%
  2. Germany8.7%
  3. China8.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Diethyl phthalate is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Diethyl phthalate, based on the data on this page

What is Diethyl phthalate?

Diethyl phthalate is the diethyl ester of benzene-1,2-dicarboxylic acid. It has a role as a teratogenic agent, a neurotoxin and a plasticiser. It is an ethyl ester, a phthalate ester and a diester.

What is the CAS number of Diethyl phthalate?

The CAS registry number of Diethyl phthalate is 84-66-2.

What is the molecular formula and weight of Diethyl phthalate?

The molecular formula of Diethyl phthalate is C12H14O4 and its molar mass is 222.24 g/mol.

What is Diethyl phthalate used for?

In mfr celluloid, solvent for cellulose acetate in mfr varnishes and dopes, denaturing alcohol. Vehicle for fragrance and cosmetic ingredients. Solvent for nitrocellulose and cellulose acetate, plasticizer, wetting agent, ... camphor substitute, plastics, perfumery as fixative and solvent, alcohol denaturant, ...

Is Diethyl phthalate hazardous?

No GHS hazard classification for Diethyl phthalate is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Diethyl phthalate?

Diethyl phthalate is usually classified under HS code 291734 (Aromatic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Diethyl phthalate?

CompoundList lists 148 suppliers of Diethyl phthalate in India, United States, China, Canada and 19 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Diethyl phthalate in India?

49 suppliers in India list Diethyl phthalate on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Diethyl phthalate?

Suppliers quote Diethyl phthalate on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Diethyl phthalate

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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