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Respiratory, allergy and digestive drugs

Bisacodyl

Also known as Dulcolax, Theralax, Sk-bisacodyl

CAS 603-50-9Formula C22H19NO4Molar mass 361.40 g/molEC 210-044-4
GHS signal word: Warning. Pictograms: Harmful or irritant 144 suppliers listed Drug substance
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Bisacodyl chemical structure, C22H19NO4, CAS 603-50-9
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
White to off-white crystalline powder in which particles having longest diameter smaller…
Melting point
138 °C
Solubility
Practically insoluble in water and alkaline solvents. Soluble in acids, alcohol, acetone…
HS code
293339
Category
Respiratory, allergy and digestive drugs
Illustrative photo, off-white crystalline powder in fibre drums in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Bisacodyl?

Plain description, key identifiers and synonyms

Bisacodyl is a diarylmethane.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[4-[(4-acetyloxyphenyl)-pyridin-2-ylmethyl]phenyl] acetate
CAS number
603-50-9 CAS number cross-checked
EC number
210-044-4
Molecular formula
C22H19NO4
UNII
10X0709Y6I
MDL number
MFCD00038039
InChIKey
KHOITXIGCFIULA-UHFFFAOYSA-N
InChI
InChI=1S/C22H19NO4/c1-15(24)26-19-10-6-17(7-11-19)22(21-5-3-4-14-23-21)18-8-12-20(13-9-18)27-16(2)25/h3-14,22H,1-2H3
SMILES (canonical and isomeric)
CC(=O)OC1=CC=C(C=C1)C(C2=CC=C(C=C2)OC(=O)C)C3=CC=CC=N3

Synonyms

  • Dulcolax
  • Theralax
  • Sk-bisacodyl
  • Brocalax
  • Dulcolan
  • Fenilaxan
  • Laxans
  • Pyrilax
  • Telemin
  • Endokolat
  • Eulaxan
  • Godalax
  • Hillcolax
  • Laxadin
  • Laxorex
  • Nigalax
  • Stadalax
  • Ivilax
  • Laxine
  • Neolax
  • Zetrax
  • Bisacodilo
  • Deficol
  • Modane
  • LACO
Show all 39 synonyms
  • Evac-Q-Tabs
  • LA96a
  • Phenol, 4,4'-(2-pyridinylmethylene)bis-, diacetate (ester)
  • Bisacodylum
  • Feen-a-Mint Tablets
  • Bis(p-acetoxyphenyl)-2-pyridylmethane
  • Di-(p-acetoxyphenyl)-2-pyridylmethane
  • Di-(4-acetoxyphenyl)-2-pyridylmethane
  • 2-(4,4'-Diacetoxydiphenylmethyl)pyridine
  • Correctol Tablets, Caplets
  • (4,4'-Diacetoxydiphenyl)(2-pyridyl)methane
  • 4,4'-(2-Pyridylmethylene)diphenol diacetate
  • Phenol, 4,4'-(2-pyridylmethylene)di-, diacetate (ester)
  • 5-21-05-00415 (Beilstein Handbook Reference)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
White to off-white crystalline powder in which particles having longest diameter smaller than 50 microns predominateexp.
Taste
Tastelessexp.
Melting point
138 °Cexp.
Solubility
Practically insoluble in water and alkaline solvents. Soluble in acids, alcohol, acetone, propylene glycol and other organic solvents.exp.
Vapour pressure
4.8 × 10⁻⁸ mm Hg at 25 °C /Estimated/exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
361.40 g/molcalc.
Exact mass
361.1314 Dacalc.
LogP (octanol/water)
4.11calc.
Topological polar surface area
65.49 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
5calc.
Heavy atoms
27calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.14calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(C(c2ccccc2)c2ccccn2)cc1

c1ccc(C(c2ccccc2)c2ccccn2)cc1

3 rings, 19 atoms, the 2-Benzhydrylpyridine ring system.

53 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (19)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Bisacodyl suppliers

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All 144 suppliers
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Where suppliers are based

144 suppliers in 21 countries

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Bisacodyl price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Cathartic.

Pharmacological actions

  • Cathartics
  • Laxatives

Roles

  • laxative
  • pharmaceutical

Pharmacology

Bisacodyl is a Stimulant Laxative. The physiologic effect of bisacodyl is by means of Increased Large Intestinal Motility and Stimulation Large Intestine Fluid/Electrolyte Secretion.

How it is made

Condensation of 2-pyridinecarboxaldehyde with phenol in the presence of sulfuric acid, followed by esterification with acetic anhydride and anhydrous sodium acetate

Produced by condensation of 2-pyridinealdehyde with phenol in the presence of dehydrating compounds. Subsequently, the phenolic hydroxyl groups are acetylated.

Preparation: GB 730243, A. Kottler, E. Seeger, US 2764590 (1955,1956 both to Thomae).

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Bisacodyl is traded under.

HS 2933.39Indicative HS code

Heterocyclic compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure…

World exports in 2024
$9.16B
−17.9% vs 2023, imports $10.6B
2019 to 2024
Top exporters
  1. China21.5%
  2. India * partner reported12.3%
  3. Ireland11.6%
Top importers
  1. Germany14.2%
  2. United States12.8%
  3. Brazil10.1%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Bisacodyl is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Bisacodyl, based on the data on this page

What is Bisacodyl?

Bisacodyl is a diarylmethane.

What is the CAS number of Bisacodyl?

The CAS registry number of Bisacodyl is 603-50-9.

What is the molecular formula and weight of Bisacodyl?

The molecular formula of Bisacodyl is C22H19NO4 and its molar mass is 361.40 g/mol.

What is Bisacodyl used for?

Cathartic.

Is Bisacodyl hazardous?

Bisacodyl carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Bisacodyl?

Bisacodyl is usually classified under HS code 293339 (Compounds containing an unfused pyridine ring (whether or not hydrogenated) in the…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Bisacodyl?

CompoundList lists 144 suppliers of Bisacodyl in India, United States, China, Germany and 17 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Bisacodyl in India?

39 suppliers in India list Bisacodyl on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Bisacodyl?

Suppliers quote Bisacodyl on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Bisacodyl

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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