CompoundList
Sign in
Heterocyclic building blocks

Ceftolozane

Also known as ceftolozano, ceftolozanum, CXA-101 FREE BASE

CAS 689293-68-3Formula C23H30N12O8S2Molar mass 666.70 g/molEC 974-724-9
GHS signal word: Danger. Pictograms: Serious health hazard, Hazardous to the environment 4 suppliers listed
Get quotes Compare 4 suppliers
Ceftolozane chemical structure, C23H30N12O8S2, CAS 689293-68-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
689293-68-3
Formula
C23H30N12O8S2
Molar mass
666.70 g/mol
EC number
974-724-9
HS code
294190
Category
Heterocyclic building blocks

What is Ceftolozane?

Plain description, key identifiers and synonyms

Ceftolozane is a fifth-generation cephalosporin antibiotic having (5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl and [(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino side groups located at positions 3 and 7 respectively, developed for the treatment of infections with gram-negative bacteria that have become resistant to conventional antibiotics. It is a cephalosporin and a member of thiadiazoles.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(6R,7R)-3-[[5-amino-4-(2-aminoethylcarbamoylamino)-1-methylpyrazol-2-ium-2-yl]methyl]-7-[[(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
CAS number
689293-68-3 CAS number cross-checkedOther or deprecated CAS: 1852466-67-1
EC number
974-724-9
Molecular formula
C23H30N12O8S2
UNII
37A4IES95Q
InChIKey
JHFNIHVVXRKLEF-DCZLAGFPSA-N
InChI
InChI=1S/C23H30N12O8S2/c1-23(2,20(40)41)43-31-11(15-30-21(26)45-32-15)16(36)29-12-17(37)35-13(19(38)39)9(8-44-18(12)35)6-34-7-10(14(25)33(34)3)28-22(42)27-5-4-24/h7,12,18,25H,4-6,8,24H2,1-3H3,(H7,26,27,28,29,30,32,36,38,39,40,41,42)/b31-11-/t12-,18-/m1/s1
Canonical SMILES
Cn1c(N)c(NC(=O)NCCN)c[n+]1CC1=C(C(=O)[O-])N2C(=O)C(NC(=O)C(=NOC(C)(C)C(=O)O)c3nsc(N)n3)C2SC1
Isomeric SMILES
CC(C)(C(=O)O)O/N=C(/C1=NSC(=N1)N)\C(=O)N[C@H]2[C@@H]3N(C2=O)C(=C(CS3)C[N+]4=CC(=C(N4C)N)NC(=O)NCCN)C(=O)[O-]

Synonyms

  • ceftolozano
  • ceftolozanum
  • CXA-101 FREE BASE
  • FR26 4205
  • Ceftolozane (USAN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
666.70 g/molcalc.
Exact mass
666.1751 Dacalc.
LogP (octanol/water)
-3.9calc.
Topological polar surface area
302.2 Ųcalc.
Hydrogen bond donors
7calc.
Hydrogen bond acceptors
15calc.
Rotatable bonds
12calc.
Heavy atoms
45calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.44calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Fails (3 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, N=C(C(=O)NC1C(=O)N2C=C(C[n+]3ccc[nH]3)CSC12)c1ncsn1

N=C(C(=O)NC1C(=O)N2C=C(C[n+]3ccc[nH]3)CSC12)c1ncsn1

4 rings, 25 atoms.

4 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS08: Serious health hazard
Serious health hazard
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H334May cause allergy or asthma symptoms or breathing difficulties if inhaled.
  • H373May cause damage to organs through prolonged or repeated exposure.
  • H400Very toxic to aquatic life.
  • H410Very toxic to aquatic life with long lasting effects.
Precautionary statements (11)
  • P233Keep container tightly closed.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P319Get medical help if you feel unwell.
  • P342 + P316If experiencing respiratory symptoms: Get emergency medical help immediately.
  • P391Collect spillage.
  • P403Store in a well-ventilated place.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ceftolozane suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 4 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Ceftolozane price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Anti-Bacterial Agents

Pharmacology

Ceftolozane is a Cephalosporin Antibacterial.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ceftolozane is traded under.

HS 2941.90Indicative HS code

Antibiotics, other

World exports in 2024
$6.39B
+2.3% vs 2023, imports $6.97B
2019 to 2024
Top exporters
  1. China39.7%
  2. United States11.3%
  3. Switzerland * partner reported10.9%
Top importers
  1. Italy15.0%
  2. India * partner reported12.0%
  3. China8.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ceftolozane is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ceftolozane, based on the data on this page

What is Ceftolozane?

Ceftolozane is a fifth-generation cephalosporin antibiotic having (5-amino-4-{[(2-aminoethyl)carbamoyl]amino}-1-methyl-1H-pyrazol-2-ium-2-yl)methyl and [(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-{[(2-carboxypropan-2-yl)oxy]imino}acetyl]amino side groups located at positions 3 and 7 respectively, developed for the treat…

What is the CAS number of Ceftolozane?

The CAS registry number of Ceftolozane is 689293-68-3. Other or deprecated CAS numbers: 1852466-67-1.

What is the molecular formula and weight of Ceftolozane?

The molecular formula of Ceftolozane is C23H30N12O8S2 and its molar mass is 666.70 g/mol.

What is Ceftolozane used for?

Known uses and roles of Ceftolozane include building blocks in research and laboratory and anti-bacterial agents.

Is Ceftolozane hazardous?

Ceftolozane carries the GHS signal word "Danger". Main hazards: may cause allergy or asthma symptoms or breathing difficulties if inhaled, may cause damage to organs through prolonged or repeated exposure, very toxic to aquatic life. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ceftolozane?

Ceftolozane is usually classified under HS code 294190 (Antibiotics, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ceftolozane?

CompoundList lists 4 suppliers of Ceftolozane in China, Czech Republic, India and United States. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Ceftolozane in India?

1 supplier in India list Ceftolozane on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Ceftolozane?

Suppliers quote Ceftolozane on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ceftolozane

Get quotes for Ceftolozane

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Ceftolozane
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Ceftolozane with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/ceftolozane-689293-68-3" title="Ceftolozane structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Heterocyclic building blocks or HS code 294190

4 suppliers
Free quotes, contact stays private
Get quotes