CompoundList
Sign in
Heterocyclic building blocks

CK-666

Also known as 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide, CK 666, 2-Fluoro-N-(2-(2-methyl-1H-indol-3-yl)ethyl)benzamide

CAS 442633-00-3Formula C18H17FN2OMolar mass 296.35 g/molEC 687-170-5
GHS signal word: Warning. Pictograms: Harmful or irritant 4 suppliers listed
Get quotes Compare 4 suppliers
CK-666 chemical structure, C18H17FN2O, CAS 442633-00-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
442633-00-3
Formula
C18H17FN2O
Molar mass
296.35 g/mol
EC number
687-170-5
HS code
293399
Category
Heterocyclic building blocks

What is CK-666?

Plain description, key identifiers and synonyms

CK-666 is a member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group. It is a cell-permeable inhibitor of actin assembly mediated by actin-related protein Arp2/3 complex which works by binding to Arp2/3 complex, stabilising the inactive state of the complex and preventing its movement into the active conformation. It has a role as an actin polymerisation inhibitor. It is a member of benzamides, a member of indoles and an organofluorine compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
CAS number
442633-00-3 CAS number cross-checked
EC number
687-170-5
Molecular formula
C18H17FN2O
MDL number
MFCD03036271
InChIKey
UXRKUKRXVWJFER-UHFFFAOYSA-N
InChI
InChI=1S/C18H17FN2O/c1-12-13(14-6-3-5-9-17(14)21-12)10-11-20-18(22)15-7-2-4-8-16(15)19/h2-9,21H,10-11H2,1H3,(H,20,22)
SMILES (canonical and isomeric)
CC1=C(C2=CC=CC=C2N1)CCNC(=O)C3=CC=CC=C3F

Synonyms

  • 2-fluoro-N-[2-(2-methyl-1H-indol-3-yl)ethyl]benzamide
  • CK 666
  • 2-Fluoro-N-(2-(2-methyl-1H-indol-3-yl)ethyl)benzamide
  • 3ukr
  • 2-Fluoro-N-[2-(2-methyl-1H-indol-3-yl)-ethyl]-benzamide
  • CK 666?
  • Arp2/3 Complex Inhibitor I, CK-666
  • CK-666, >=98% (HPLC), powder
  • CK-666, >98%
  • 2-Fluoro-N-[2-(2-methyl-3-indolyl)ethyl]benzamide
  • 2-Fluoro-N-[2-methyl-1H-indol-3-yl)ethyl]benzamide
  • (2-fluorophenyl)-N-[2-(2-methylindol-3-yl)ethyl]carboxamide
  • CKH

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
296.35 g/molcalc.
Exact mass
296.1325 Dacalc.
LogP (octanol/water)
3.59calc.
Topological polar surface area
44.89 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
4calc.
Heavy atoms
22calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.17calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C(NCCc1c[nH]c2ccccc12)c1ccccc1

O=C(NCCc1c[nH]c2ccccc12)c1ccccc1

3 rings, 20 atoms, the N-(2-(1H-Indol-3-yl)ethyl)benzamide ring system.

189 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H319Causes serious eye irritation.
Precautionary statements (4)
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337 + P317If eye irritation persists: Get medical help.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

CK-666 suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 4 suppliers
4 of 4 offers
  • Angel Pharmatech Ltd.
    China, ShanghaiUnclaimed profile
    CK-666Grade, purity and minimum order on request
    Price on request
    View
  • Axon Medchem
    United States, RestonUnclaimed profile
    CK-666Grade, purity and minimum order on request
    Price on request
    View
  • ChemBridge Corporation
    United States, San DiegoUnclaimed profile
    CK-666Grade, purity and minimum order on request
    Price on request
    View
  • Vitas-M Laboratory
    Hong Kong, CentralUnclaimed profile
    CK-666Grade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

4 suppliers in 3 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

CK-666 price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Roles

  • actin polymerisation inhibitor

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code CK-666 is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for CK-666 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about CK-666, based on the data on this page

What is CK-666?

CK-666 is a member of the class of indoles that is 2-methyltryptamine in which a hydrogen attached to the primary amino group has been replaced by a 2-fluorobenzoyl group.

What is the CAS number of CK-666?

The CAS registry number of CK-666 is 442633-00-3.

What is the molecular formula and weight of CK-666?

The molecular formula of CK-666 is C18H17FN2O and its molar mass is 296.35 g/mol.

What is CK-666 used for?

Known uses and roles of CK-666 include building blocks in research and laboratory, screening compounds in research and laboratory and actin polymerisation inhibitor.

Is CK-666 hazardous?

CK-666 carries the GHS signal word "Warning". Main hazards: causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of CK-666?

CK-666 is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy CK-666?

CompoundList lists 4 suppliers of CK-666 in United States, China and Hong Kong. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of CK-666?

Suppliers quote CK-666 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle CK-666

Get quotes for CK-666

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell CK-666
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of CK-666 with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/ck-666-442633-00-3" title="CK-666 structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Heterocyclic building blocks or HS code 293399

4 suppliers
Free quotes, contact stays private
Get quotes