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Nucleosides and nucleotides

Coformycin

Also known as (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol, Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-, (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol

CAS 11033-22-0Formula C11H16N4O5Molar mass 284.27 g/mol
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Coformycin chemical structure, C11H16N4O5, CAS 11033-22-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
11033-22-0
Formula
C11H16N4O5
Molar mass
284.27 g/mol
HS code
293499
Category
Nucleosides and nucleotides

What is Coformycin?

Plain description, key identifiers and synonyms

Coformycin is an N-glycosyl in which (8R)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol is attached to ribofuranose via a beta-N3-glycosidic bond. compound The parent of the class of coformycins. It has a role as an EC 3.5.4.4 (adenosine deaminase) inhibitor. It is a conjugate base of a coformycin(1+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)oxolane-3,4-diol
CAS number
11033-22-0
Molecular formula
C11H16N4O5
UNII
E49510ZL0H
InChIKey
YOOVTUPUBVHMPG-LODYRLCVSA-N
InChI
InChI=1S/C11H16N4O5/c16-2-6-8(18)9(19)11(20-6)15-4-14-7-5(17)1-12-3-13-10(7)15/h3-6,8-9,11,16-19H,1-2H2,(H,12,13)/t5-,6-,8-,9-,11-/m1/s1
Canonical SMILES
OCC1OC(n2cnc3c2NC=NCC3O)C(O)C1O
Isomeric SMILES
C1[C@H](C2=C(NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO)O)O)O

Synonyms

  • (R)-3,4,7,8-Tetrahydro-3-beta-D-ribofuranosylimidazo(4,5-d)(1,3)diazepin-8-ol
  • Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (R)-
  • (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol
  • (2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-4H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)oxolane-3,4-diol
  • (8R)-3-beta-D-ribofuranosyl-3,6,7,8-tetrahydroimidazo(4,5-d)(1,3)diazepin-8-ol
  • (2R,3R,4S,5R)-2-((8R)-8-hydroxy-7,8-dihydro-4H-imidazo(4,5-d)(1,3)diazepin-3-yl)-5-(hydroxymethyl)oxolane-3,4-diol
  • Coformycin - API Standards
  • Imidazo[4,5-d][1,3]diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-D-ribofuranosyl-, (8R)
  • Imidazo[4,5-d][1,3]diazepin-8-ol,3,4,7,8-tetrahydro-3-b-D-ribofuranosyl-, (8R)-
  • (2R,3R,4S,5R)-2-[(8R)-8-hydroxy-7,8-dihydro-6H-imidazo[4,5-d][1,3]diazepin-3-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol
  • Imidazo(4,5-d)(1,3)diazepin-8-ol, 3,4,7,8-tetrahydro-3-beta-d-ribofuranosyl-, (8R)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
284.27 g/molcalc.
Exact mass
284.1121 Dacalc.
LogP (octanol/water)
-2.02calc.
Topological polar surface area
132.4 Ųcalc.
Hydrogen bond donors
5calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
2calc.
Heavy atoms
20calc.
Rings
3calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.64calc.
Formal charge
0calc.
Stereocentres
5calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=NCCc2ncn(C3CCCO3)c2N1

C1=NCCc2ncn(C3CCCO3)c2N1

3 rings, 15 atoms.

6 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Coformycin suppliers

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Coformycin price

Indicative price range per kg from live supplier offers

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Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antibiotics, Antineoplastic
  • Enzyme Inhibitors
  • Immunosuppressive Agents

Roles

  • antineoplastic agent
  • enzyme inhibitor
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Coformycin is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Coformycin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Coformycin, based on the data on this page

What is Coformycin?

Coformycin is an N-glycosyl in which (8R)-3,6,7,8-tetrahydroimidazo[4,5-d][1,3]diazepin-8-ol is attached to ribofuranose via a beta-N3-glycosidic bond. compound The parent of the class of coformycins. It has a role as an EC 3.5.4.4 (adenosine deaminase) inhibitor. It is a conjugate base of a coformycin(1+).

What is the CAS number of Coformycin?

The CAS registry number of Coformycin is 11033-22-0.

What is the molecular formula and weight of Coformycin?

The molecular formula of Coformycin is C11H16N4O5 and its molar mass is 284.27 g/mol.

What is Coformycin used for?

Known uses and roles of Coformycin include biochemical and pharmacological tools in research and laboratory, antineoplastic agent, enzyme inhibitor, pharmaceutical, antibiotics, antineoplastic and 2 more.

Is Coformycin hazardous?

No GHS hazard classification for Coformycin is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Coformycin?

Coformycin is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Coformycin?

Post a free request on CompoundList and suppliers of Coformycin will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Coformycin?

Suppliers quote Coformycin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Coformycin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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