Cridanimod
Also known as 10-Carboxymethyl-9-acridanone, 10(9H)-acridineacetic acid, 9-oxo-, N-(Carboxymethyl)acridone
Key facts
What buyers check first
- CAS number
- 38609-97-1
- Formula
- C15H11NO3
- Molar mass
- 253.26 g/mol
- EC number
- 634-833-1
- HS code
- 293399
- Category
- Heterocyclic building blocks
What is Cridanimod?
Plain description, key identifiers and synonyms
Cridanimod is a member of acridines. It is functionally related to an acridone.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-(9-oxoacridin-10-yl)acetic acid
- CAS number
- 38609-97-1 CAS number cross-checked
- EC number
- 634-833-1
- Molecular formula
- C15H11NO3
- UNII
- X91E9EME19
- MDL number
- MFCD00157050
- InChIKey
- UOMKBIIXHQIERR-UHFFFAOYSA-N
- InChI
- InChI=1S/C15H11NO3/c17-14(18)9-16-12-7-3-1-5-10(12)15(19)11-6-2-4-8-13(11)16/h1-8H,9H2,(H,17,18)
- SMILES (canonical and isomeric)
- C1=CC=C2C(=C1)C(=O)C3=CC=CC=C3N2CC(=O)O
Synonyms
- 10-Carboxymethyl-9-acridanone
- 10(9H)-acridineacetic acid, 9-oxo-
- N-(Carboxymethyl)acridone
- 2-(9-Oxo-9,10-dihydroacridin-10-yl)acetic acid
- cridanimodum
- acridone N-methyl-N-(alpha,D-glucopyranosyl)ammonium 10-methylenecarboxylate
- 9-Oxo-10-acridineacetic acid
- 9-Oxo-10(9H)-acridineacetic acid
- 2-(9-oxoacridin-10(9H)-yl)acetic acid
- 2-(9-oxoacridin-10-yl)acetic acid
- (9-oxoacridin-10(9H)-yl)acetic acid
- 9-oxoacridine-10-acetic acid
- Cycloferon
- 9-Oxo-10-acridanacetic acid
- (9-Oxo-9 H -acridin-10-yl)-acetic acid
- Cridanimod (INN)
- 10-(Carboxymethyl)-9(10H)-acridone
- (9-Oxo-10(9H)-acridinyl)acetic acid
- Cyclopheron
- XBIO-101
- 10-Carboxymeth-9-acridanone
- 2-(9-oxo-10-hydroacridin-10-yl)acetic acid
- Cridanimod?
- 38609-97-1 (free acid)
- 10-(Carboxymethyl)-9(10H)acridone
Show all 32 synonymsShow fewer synonyms
- 10-Carboxymethylacridanone
- 5-21-09-00011 (Beilstein Handbook Reference)
- 2-(9-oxo-10-a
- 2-(9-oxoacridin-10-yl)aceticacid
- 10-(Carboxymethyl)-9-acridinone
- (9-Oxo-10(9H)-acridinyl)acetic acid #
- Acetic acid, 9(10H)-oxo-10-acridinyl-
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 253.26 g/molcalc.Computed value |
|---|---|
| Exact mass | 253.0739 Dacalc.Computed value |
| LogP (octanol/water) | 2.24calc.Computed value |
| Topological polar surface area | 59.3 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 2calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 19calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 3calc.Computed value |
| Fraction sp3 carbons | 0.07calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
O=c1c2ccccc2[nH]c2ccccc12
3 rings, 15 atoms, the Acridone ring system.
362 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
Hazard statements
- H315Causes skin irritation.
- H319Causes serious eye irritation.
- H335May cause respiratory irritation.
Precautionary statements (16)
- P261Avoid breathing dust, fume, gas, mist, vapours or spray.
- P264Wash skin thoroughly after handling.
- P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
- P271Use only outdoors or in a well-ventilated area.
- P280Wear protective gloves, protective clothing, eye protection and face protection.
- P302 + P352If on skin: Wash with plenty of water.
- P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
- P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
- P319Get medical help if you feel unwell.
- P321Specific treatment (see supplemental first aid instructions on the label).
- P332 + P317If skin irritation occurs: Get medical help.
- P337 + P317If eye irritation persists: Get medical help.
- P362 + P364Take off contaminated clothing. And wash it before reuse.
- P403 + P233Store in a well-ventilated place. Keep container tightly closed.
- P405Store locked up.
- P501Dispose of contents and container in accordance with local regulations.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Full safety data and first aidCridanimod suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- Price on request
- China, Lianyungang ManufacturerUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- United States ManufacturerUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- Turkey ManufacturerUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- United States, HaywardUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- GermanyUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- Singapore, SingaporeUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- Hong Kong, Hong KongUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
- Price on request
- United StatesUnclaimed profileCridanimodGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
30 suppliers in 9 countries
- United States13
- China7
- Hong Kong2
- Ukraine2
- Germany1
- France1
- and 3 more countries
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Cridanimod price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Interferon Inducers
Roles
- antineoplastic agent
- pharmaceutical
Pharmacology
Cridanimod is a small molecule that can increase progesterone receptor (PR) expression, with potential antineoplastic adjuvant activity. Upon intramuscular administration, cridanimod is able to induce the expression of PR in endometrial cancer. This could increase the sensitivity of endometrial cancer cells to progestin monotherapy.
Read more
In combination with a progestin, cancer cells could be eradicated through increased PR-mediated signaling, leading to an inhibition of luteinizing hormone (LH) release from the pituitary gland, via a negative feedback mechanism, and, eventually, an inhibition of estrogen release from the ovaries. This leads to an inhibition of cellular growth in estrogen-dependent tumor cells. In addition, this agent is able to increase the production and release of interferon (IFN) alpha and beta. PR is often downregulated in endometrial cancer and makes it resistant to progestin-mediated hormone therapy.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Cridanimod is traded under.
Heterocyclic compounds with nitrogen hetero-atom(s) only, other
- Slovenia31.7%
- Italy24.2%
- United States5.0%
* Partner reported figures, a lower bound.
The HS code shown for Cridanimod is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Cridanimod, based on the data on this page
What is Cridanimod?
What is the CAS number of Cridanimod?
What is the molecular formula and weight of Cridanimod?
What is Cridanimod used for?
Is Cridanimod hazardous?
What is the HS code of Cridanimod?
Where can I buy Cridanimod?
What is the price of Cridanimod?
Guides for buyers
Practical guides that help when you source, ship or handle Cridanimod
- Guide, SafetyHow to read a safety data sheet in 10 minutesA section by section method to pull the essentials out of any 16 section SDS: identity, hazards, composition, storage, PPE, properties, transport and emergency measures.Read
- Guide, SafetyGHS pictograms, signal words and hazard statements explainedA practical guide to the nine GHS pictograms, the signal words Danger and Warning, H and P statements, and how to read a chemical label in seconds.Read
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
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