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Amino acids and derivatives

D-Methionine

Also known as (R)-Methionine, D-Methionin, D-Metionien

CAS 348-67-4Formula C5H11NO2SMolar mass 149.22 g/molEC 206-483-6
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D-Methionine chemical structure, C5H11NO2S, CAS 348-67-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
348-67-4
Formula
C5H11NO2S
Molar mass
149.22 g/mol
EC number
206-483-6
HS code
293040
Category
Amino acids and derivatives

What is D-Methionine?

Plain description, key identifiers and synonyms

D-methionine is an optically active form of methionine having D-configuration. It is a D-alpha-amino acid and a methionine. It is a conjugate base of a D-methioninium. It is a conjugate acid of a D-methioninate. It is an enantiomer of a L-methionine. It is a tautomer of a D-methionine zwitterion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-2-amino-4-methylsulfanylbutanoic acid
CAS number
348-67-4 CAS number cross-checked
EC number
206-483-6
Molecular formula
C5H11NO2S
UNII
868496F25R
MDL number
MFCD00002622
InChIKey
FFEARJCKVFRZRR-SCSAIBSYSA-N
InChI
InChI=1S/C5H11NO2S/c1-9-3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)/t4-/m1/s1
Canonical SMILES
CSCCC(N)C(=O)O
Isomeric SMILES
CSCC[C@H](C(=O)O)N

Synonyms

  • (R)-Methionine
  • D-Methionin
  • D-Metionien
  • (R)-2-amino-4-(methylthio)butanoic acid
  • Methionine, d-
  • Methionine D-
  • Methionine d-form
  • D-Metionien [Australian]
  • (2R)-2-amino-4-(methylsulfanyl)butanoic acid
  • (2R)-2-amino-4-methylsulfanylbutanoic acid
  • D-2-Amino-4-(methylthio)butyric acid
  • D-Metionien (Australian)
  • H-D-Met-OH
  • MRx-1024
  • D-2-Amino-4-(methylthio)butanoic acid
  • R-Methionine
  • MED
  • D-Methionine, puriss., >=99.0% (NT)
  • (R)-2-Amino-4-(methylmercapto)butyric acid
  • (R)-Methionine, MRX 1024, NSC 45689, S-Methyl-D-homocysteine
  • D-Met
  • D-Met-OH
  • (2R)-2-amino-
  • D-Methionine, MRX-1024
  • MRX-1024,D-Methionine
Show all 27 synonyms
  • S-Methyl-d-homocysteine
  • D-Methionine, >=98% (HPLC)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
149.22 g/molcalc.
Exact mass
149.0511 Dacalc.
LogP (octanol/water)
0.15calc.
Topological polar surface area
63.32 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
4calc.
Heavy atoms
9calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.8calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

D-Methionine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 17 suppliers
17 of 17 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

17 suppliers in 3 countries

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D-Methionine price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Roles

  • Escherichia coli metabolite
  • Saccharomyces cerevisiae metabolite
  • bacterial metabolite
  • eukaryotic metabolite
  • fungal metabolite
  • metabolite
  • prokaryotic metabolite

Pharmacology

D-methionine Formulation MRX-1024 is a proprietary oral formulation of D-methionine with antioxidant and antimucositis activities. D-methionine formulation MRX-1024 may selectively protect the oral mucosa from the toxic effects of chemotherapy and radiation therapy without compromising antitumor activity. D-methionine may be converted into the L- isomer in vivo, particularly in instances of L-methionine deprivation, both isomers have antioxidant activity which may be due, in part, to their sulfur moieties and chelating properties. L-methionine, an essential amino acid, also may help to maintain the ratio of reduced glutathione to oxidized glutathione in cells undergoing oxidative stress and may provide a source of L-cysteine for glutathione synthesis.

Regulatory status

Inventories, regulations and trade controls that list this substance

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code D-Methionine is traded under.

HS 2930.40Indicative HS code

Methionine

World exports in 2024
$1.06B
+49.3% vs 2023, imports $2.16B
2019 to 2024
Top exporters
  1. China56.8%
  2. Malaysia17.4%
  3. France * partner reported8.7%
Top importers
  1. China17.4%
  2. Brazil7.6%
  3. Germany5.4%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for D-Methionine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about D-Methionine, based on the data on this page

What is D-Methionine?

D-methionine is an optically active form of methionine having D-configuration. It is a D-alpha-amino acid and a methionine. It is a conjugate base of a D-methioninium. It is a conjugate acid of a D-methioninate. It is an enantiomer of a L-methionine. It is a tautomer of a D-methionine zwitterion.

What is the CAS number of D-Methionine?

The CAS registry number of D-Methionine is 348-67-4.

What is the molecular formula and weight of D-Methionine?

The molecular formula of D-Methionine is C5H11NO2S and its molar mass is 149.22 g/mol.

What is D-Methionine used for?

Known uses and roles of D-Methionine include escherichia coli metabolite, saccharomyces cerevisiae metabolite, bacterial metabolite, eukaryotic metabolite, fungal metabolite and 2 more.

Is D-Methionine hazardous?

No GHS hazard classification for D-Methionine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of D-Methionine?

D-Methionine is usually classified under HS code 293040 (Methionine). This is indicative, confirm it with your customs broker before shipping.

Where can I buy D-Methionine?

CompoundList lists 17 suppliers of D-Methionine in China, United States and India. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy D-Methionine in India?

1 supplier in India list D-Methionine on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of D-Methionine?

Suppliers quote D-Methionine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle D-Methionine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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