(±)-Ethopropazine (CAS 522-00-9): price, suppliers and safety

What is (±)-Ethopropazine?

Plain description, key identifiers and synonyms

Profenamine is a member of the class of phenothiazines that is phenothiazine in which the hydrogen attached to the nitrogen is substituted by a 2-(diethylamino)propyl group. An antimuscarinic, it is used as the hydrochloride for the symptomatic treatment of Parkinson's disease. It has a role as an adrenergic antagonist, a histamine antagonist, an antiparkinson drug, a muscarinic antagonist and an antidyskinesia agent. It is a member of phenothiazines and a tertiary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name: N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine
CAS number: 522-00-9 CAS number cross-checkedOther or deprecated CAS: 1094-08-2
EC number: 208-320-4
Molecular formula: C₁₉H₂₄N₂S
UNII: 7WI4P02YN1
InChIKey: CDOZDBSBBXSXLB-UHFFFAOYSA-N
InChI: InChI=1S/C19H24N2S/c1-4-20(5-2)15(3)14-21-16-10-6-8-12-18(16)22-19-13-9-7-11-17(19)21/h6-13,15H,4-5,14H2,1-3H3
SMILES (canonical and isomeric): CCN(CC)C(C)CN1C2=CC=CC=C2SC3=CC=CC=C31

Synonyms

ethopropazine
Profenamine
Ethopromazine
Profenaminum
Profenamina
2-Diethylamino-1-propyl-N-dibenzoparathiazine
N,N-Diethyl-alpha-methyl-10H-phenothiazine-10-ethanamine
(+-)-Ethopropazine
10-[2-(Diethylamino)propyl]phenothiazine
10-[2-(Diethylamino)-1-Propyl]phenothiazine
10H-Phenothiazine-10-ethanamine, N,N-diethyl-alpha-methyl-
10-[2-(Diethylamino)-2-methylethyl]phenothiazine
Phenothiazine, 10-(2-(diethylamino)propyl)-
diethyl[1-(10H-phenothiazin-10-yl)propan-2-yl]amine
N,N-Diethyl-1-(10H-phenothiazin-10-yl)-2-propanamine
10-(2-(Diethylamino)propyl)phenothiazine
10-(2-(diethylamino)-1-propyl)phenothiazine
Phenothiazine, 10-[2-(diethylamino)propyl]-
10-(2-(diethylamino)-2-methylethyl)phenothiazine
diethyl(1-(10H-phenothiazin-10-yl)propan-2-yl)amine
Isothazine
Isothiazine
Parsidol
Phenopropazine
Prophenamine

Show all 36 synonyms

Parsitan
Prophenaminum
Parsotil
Rodipal
Ethapropazine
Parfezine
Isopthazine
Fempropazine
10-(2-Diethylaminopropyl)phenothiazine
N,N-diethyl-1-phenothiazin-10-ylpropan-2-amine
SKF 2538

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight	312.48 g/molcalc.
Exact mass	312.166 Dacalc.
LogP (octanol/water)	5.02calc.
Topological polar surface area	6.48 Å²calc.
Hydrogen bond donors	0calc.
Hydrogen bond acceptors	3calc.
Rotatable bonds	5calc.
Heavy atoms	22calc.
Rings	3calc.
Aromatic rings	2calc.
Fraction sp3 carbons	0.37calc.
Formal charge	0calc.
Stereocentres	1calc.
Lipinski rule of five	Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

c1ccc2c(c1)Nc1ccccc1S2

3 rings, 14 atoms, the Phenothiazine ring system.

1,001 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

(±)-Ethopropazine suppliers

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(±)-Ethopropazine price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

CNS agents in pharmaceuticals

Pharmacological actions

Adrenergic Antagonists
Histamine Antagonists
Muscarinic Antagonists

Roles

adrenergic agent
adrenergic antagonist
antagonist
antidyskinesia agent
antiparkinson drug
cholinergic antagonist
cholinergic drug
histamine antagonist
histaminergic drug
muscarinic antagonist
neurotransmitter agent
pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (±)-Ethopropazine is traded under.

HS 2934.30Indicative HS code

Compounds containing in the structure a phenothiazine ring-system (whether or not…

World exports in 2024

$89.3M

−7.1% vs 2023, imports $97M

2019 to 2024

Top exporters

Germany21.6%
France * partner reported14.6%
China13.0%

Top importers

United States14.2%
Brazil12.7%
India * partner reported10.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for (±)-Ethopropazine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Parent and salt forms, stereoisomers, similar structures and isomers

Salt and hydrate forms

Records that share this compound as their parent

Ethopropazine hydrochloride chemical structure, C19H25ClN2S, CAS 1094-08-2

Ethopropazine hydrochloride1094-08-2C₁₉H₂₅ClN₂S3 suppliers

Stereoisomers and isotopic forms

Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)

(R)-Profenamine chemical structure, C19H24N2S, CAS 852369-53-0

(R)-Profenamine852369-53-0C₁₉H₂₄N₂S

(S)-Ethopropazine chemical structure, C19H24N2S, CAS 852369-52-9

(S)-Ethopropazine852369-52-9C₁₉H₂₄N₂S

Similar structures

Nearest neighbours by Morgan fingerprint Tanimoto similarity

Promethazine chemical structure, C17H20N2S, CAS 60-87-7

(+)-Promethazine chemical structure, C17H20N2S, CAS 67253-23-0

71% similar

(+)-Promethazine67253-23-0C₁₇H₂₀N₂S

Promethazine hydrochloride chemical structure, C17H21ClN2S, CAS 58-33-3

Promethazine-d6 hydrochloride chemical structure, C17H21ClN2S, CAS 1189947-02-1

Promethazine-[d3] HCl chemical structure, C17H21ClN2S, CAS 1435933-86-0

Same formula isomers

Different compounds that share this molecular formula

All isomers

10-(3-(Diethylamino)propyl)phenothiazine chemical structure, C19H24N2S, CAS 47205-14-1

10-(3-(Diethylamino)propyl)phenothiazine47205-14-1C₁₉H₂₄N₂S

1-(2-(Dimethylamino)ethyl)-2-phenyl-5,6,7,8-tetrahydroquinoline-4(1H)-thione chemical structure, C19H24N2S, CAS 691369-82-1

1-(2-(Dimethylamino)ethyl)-2-phenyl-5,6,7,8-tetrahydroquinoline-4(1H)-thione691369-82-1C₁₉H₂₄N₂S

Phenothiazine, 10-(2,2-dimethyl-3-dimethylaminopropyl)- chemical structure, C19H24N2S, CAS 4335-05-1

Phenothiazine, 10-(2,2-dimethyl-3-dimethylaminopropyl)-4335-05-1C₁₉H₂₄N₂S

1-(Biphenyl-4-yl)-3-hexylthiourea chemical structure, C19H24N2S, CAS 1415559-64-6

1-(Biphenyl-4-yl)-3-hexylthiourea1415559-64-6C₁₉H₂₄N₂S

Phenothiazine, 10-(1-methyl-1-diethylaminoethyl)- chemical structure, C19H24N2S, CAS 63834-13-9

Phenothiazine, 10-(1-methyl-1-diethylaminoethyl)-63834-13-9C₁₉H₂₄N₂S

Thiourea, N,N'-bis(2,4,6-trimethylphenyl)- chemical structure, C19H24N2S, CAS 29555-12-2

Thiourea, N,N'-bis(2,4,6-trimethylphenyl)-29555-12-2C₁₉H₂₄N₂S

N-(2,6-Diisopropylphenyl)-N'-phenylthiourea chemical structure, C19H24N2S, CAS 32978-17-9

N-(2,6-Diisopropylphenyl)-N'-phenylthiourea32978-17-9C₁₉H₂₄N₂S

1-Pentyl-2-phenyl-5,6,7,8-tetrahydro-4(1H)-quinazolinethione chemical structure, C19H24N2S, CAS 371143-76-9

1-Pentyl-2-phenyl-5,6,7,8-tetrahydro-4(1H)-quinazolinethione371143-76-9C₁₉H₂₄N₂S

1-(4-Butylphenyl)-3-(2-phenylethyl)thiourea chemical structure, C19H24N2S, CAS 502479-64-3

1-(4-Butylphenyl)-3-(2-phenylethyl)thiourea502479-64-3C₁₉H₂₄N₂S

8-[[(Octahydro-2H-quinolizin-1-yl)methyl]thio]-quinoline chemical structure, C19H24N2S, CAS 780792-70-3

8-[[(Octahydro-2H-quinolizin-1-yl)methyl]thio]-quinoline780792-70-3C₁₉H₂₄N₂S

1-Benzyl-4-[(4-methylsulfanylphenyl)methyl]piperazine chemical structure, C19H24N2S, CAS 414889-37-5

1-Benzyl-4-[(4-methylsulfanylphenyl)methyl]piperazine414889-37-5C₁₉H₂₄N₂S

1-Benzyl-N-(4-methylsulfanylphenyl)piperidin-4-amine chemical structure, C19H24N2S, CAS 864424-22-6

1-Benzyl-N-(4-methylsulfanylphenyl)piperidin-4-amine864424-22-6C₁₉H₂₄N₂S

Frequently asked questions

Quick answers about (±)-Ethopropazine, based on the data on this page

What is (±)-Ethopropazine?

Profenamine is a member of the class of phenothiazines that is phenothiazine in which the hydrogen attached to the nitrogen is substituted by a 2-(diethylamino)propyl group. An antimuscarinic, it is used as the hydrochloride for the symptomatic treatment of Parkinson's disease.

What is the CAS number of (±)-Ethopropazine?

The CAS registry number of (±)-Ethopropazine is 522-00-9. Other or deprecated CAS numbers: 1094-08-2.

What is the molecular formula and weight of (±)-Ethopropazine?

The molecular formula of (±)-Ethopropazine is C19H24N2S and its molar mass is 312.48 g/mol.

What is (±)-Ethopropazine used for?

Use classes: Pharmaceuticals.

Is (±)-Ethopropazine hazardous?

No GHS hazard classification for (±)-Ethopropazine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of (±)-Ethopropazine?

(±)-Ethopropazine is usually classified under HS code 293430 (Compounds containing in the structure a phenothiazine ring-system (whether or not…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (±)-Ethopropazine?

Post a free request on CompoundList and suppliers of (±)-Ethopropazine will send you quotes. Your contact details stay private until you accept a quote.

What is the price of (±)-Ethopropazine?

Suppliers quote (±)-Ethopropazine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (±)-Ethopropazine

(±)-Ethopropazine

Key facts

What is (±)-Ethopropazine?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

(±)-Ethopropazine suppliers

(±)-Ethopropazine price

Uses and applications

Industries and functions

Pharmacological actions

Roles

Regulatory status

HS code and trade data

Global trade

Frequently asked questions

What is (±)-Ethopropazine?

What is the CAS number of (±)-Ethopropazine?

What is the molecular formula and weight of (±)-Ethopropazine?

What is (±)-Ethopropazine used for?

Is (±)-Ethopropazine hazardous?

What is the HS code of (±)-Ethopropazine?

Where can I buy (±)-Ethopropazine?

What is the price of (±)-Ethopropazine?

Guides for buyers

Get quotes for (±)-Ethopropazine

Key facts

What is (±)-Ethopropazine?

Identifiers

Synonyms

Physical and chemical properties

Physical and chemical properties

Computed descriptors

Murcko scaffold

Safety and hazards

(±)-Ethopropazine suppliers

(±)-Ethopropazine price

Uses and applications

Industries and functions

Pharmacological actions

Roles

Regulatory status

HS code and trade data

Global trade

Related chemicals

Salt and hydrate forms

Stereoisomers and isotopic forms

Similar structures

Same formula isomers

Frequently asked questions

What is (±)-Ethopropazine?

What is the CAS number of (±)-Ethopropazine?

What is the molecular formula and weight of (±)-Ethopropazine?

What is (±)-Ethopropazine used for?

Is (±)-Ethopropazine hazardous?

What is the HS code of (±)-Ethopropazine?

Where can I buy (±)-Ethopropazine?

What is the price of (±)-Ethopropazine?

Guides for buyers

Get quotes for (±)-Ethopropazine