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Dyes and pigments

Fisetin

Also known as 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one, 5-Desoxyquercetin, 3,3',4',7-Tetrahydroxyflavone

CAS 528-48-3Formula C15H10O6Molar mass 286.24 g/molEC 208-434-4
GHS signal word: Warning. Pictograms: Harmful or irritant 100 suppliers listed
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Fisetin chemical structure, C15H10O6, CAS 528-48-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
528-48-3
Formula
C15H10O6
Molar mass
286.24 g/mol
EC number
208-434-4
HS code
293299
Category
Dyes and pigments

What is Fisetin?

Plain description, key identifiers and synonyms

Fisetin is a 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'. It has a role as a geroprotector, an antioxidant, a metabolite, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-inflammatory agent and a plant metabolite. It is a 3'-hydroxyflavonoid, a tetrahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a fisetin(1-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
CAS number
528-48-3 CAS number cross-checked
EC number
208-434-4
Molecular formula
C15H10O6
UNII
OO2ABO9578
MDL number
MFCD00006829
INCI name
FISETIN
InChIKey
XHEFDIBZLJXQHF-UHFFFAOYSA-N
InChI
InChI=1S/C15H10O6/c16-8-2-3-9-12(6-8)21-15(14(20)13(9)19)7-1-4-10(17)11(18)5-7/h1-6,16-18,20H
SMILES (canonical and isomeric)
C1=CC(=C(C=C1C2=C(C(=O)C3=C(O2)C=C(C=C3)O)O)O)O

Synonyms

  • 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-chromen-4-one
  • 5-Desoxyquercetin
  • 3,3',4',7-Tetrahydroxyflavone
  • 3,7,3',4'-Tetrahydroxyflavone
  • Fustet
  • Fisetholz
  • Superfustel
  • Cotinin
  • Fietin
  • Fustel
  • Viset
  • Junger fustik
  • C.I. Natural Brown 1
  • C.I. 75620
  • Fisidenolon 1521
  • 2-(3,4-Dihydroxyphenyl)-3,7-dihydroxy-4H-1-benzopyran-4-one
  • 7,3',4'-Trihydroxyflavonol
  • 2-(3,4-dihydroxyphenyl)-3,7-dihydroxychromen-4-one
  • 5-Desoxy-quercetin
  • 7,3',4'-Flavon-3-ol
  • 3,3',4',7-Tetrahydroxy-flavone
  • 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-1-benzopyrylium
  • Ventin sumach
  • Young fustic
  • Zante fustic
Show all 37 synonyms
  • Superfustel K
  • Ungarisches gelbholz
  • Young fustic crystals
  • Bois bleu de Honqrie
  • Fisetin (Standard)
  • 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-
  • 5-Deoxyquercetin
  • 3,4',7-Tetrahydroxyflavone
  • 2-(3,4-dihydroxyphenyl)-3,7-dihydroxy-chromen-4-one
  • Flavone, 3,3',4',7-tetrahydroxy-
  • BOIS bleude honqrie
  • FSE

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
286.24 g/molcalc.
Exact mass
286.0477 Dacalc.
LogP (octanol/water)
2.28calc.
Topological polar surface area
111.1 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc(-c2ccccc2)oc2ccccc12

O=c1cc(-c2ccccc2)oc2ccccc12

3 rings, 17 atoms, the Flavone ring system.

2,273 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Fisetin suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 100 suppliers
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Where suppliers are based

100 suppliers in 14 countries

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Fisetin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name FISETIN(colorant, skin conditioning)

Roles

  • anti-inflammatory agent
  • antimicrobial agent
  • antineoplastic agent
  • antioxidant
  • antiviral agent
  • enzyme inhibitor
  • eukaryotic metabolite
  • geroprotector
  • metabolite
  • pharmaceutical
  • plant metabolite
  • protective agent
  • topoisomerase inhibitor

Functional uses

  • Dye
  • Softener and conditioner

Cosmetic functions

  • Colorant
  • Skin conditioning

Pharmacology

Fisetin is an orally bioavailable naturally occurring polyphenol found in many fruits and vegetables, with potential antioxidant, neuroprotective, anti-inflammatory, antineoplastic, senolytic, and longevity promoting activities. Upon administration, fisetin, as an antioxidant, scavenges free radicals, protect cells from oxidative stress, and is able to upregulate glutathione. It inhibits pro-inflammatory mediators, such as tumor necrosis factor alpha (TNF-a), interleukin-6 (IL-6), and nuclear factor kappa B (NF-kB).

Read more

Fisetin promotes cellular metabolism, reduces senescence, regulates sirtuin function and may promote longevity. Fisetin also exerts anti-cancer activity by inhibiting certain signaling pathways. It also inhibits certain anti-apoptotic proteins and induces apoptosis in susceptible cells.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

United States

  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Fisetin is traded under.

HS 2932.99Indicative HS code

Heterocyclic compounds with oxygen hetero-atom(s) only, other

World exports in 2024
$3.81B
+10.3% vs 2023, imports $7.05B
2019 to 2024
Top exporters
  1. China28.9%
  2. Switzerland * partner reported12.7%
  3. Germany7.8%
Top importers
  1. United States49.7%
  2. China11.9%
  3. India * partner reported3.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Fisetin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Fisetin, based on the data on this page

What is Fisetin?

Fisetin is a 7-hydroxyflavonol with additional hydroxy groups at positions 3, 3' and 4'. It has a role as a geroprotector, an antioxidant, a metabolite, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, an anti-inflammatory agent and a plant metabolite.

What is the CAS number of Fisetin?

The CAS registry number of Fisetin is 528-48-3.

What is the molecular formula and weight of Fisetin?

The molecular formula of Fisetin is C15H10O6 and its molar mass is 286.24 g/mol.

What is Fisetin used for?

Known uses and roles of Fisetin include skin conditioning agents in cosmetics and personal care, colorants in cosmetics and personal care, anti-inflammatory agent, antimicrobial agent, antineoplastic agent and 14 more.

Is Fisetin hazardous?

Fisetin carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Fisetin?

Fisetin is usually classified under HS code 293299 (Heterocyclic compounds with oxygen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Fisetin?

CompoundList lists 100 suppliers of Fisetin in China, United States, United Kingdom, Canada and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Fisetin?

Suppliers quote Fisetin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Fisetin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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