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Flavonoids and polyphenols

Kaempferol

Also known as Kaempherol, Robigenin, Rhamnolutein

CAS 520-18-3Formula C15H10O6Molar mass 286.24 g/molEC 208-287-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Serious health hazard 102 suppliers listed
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Kaempferol chemical structure, C15H10O6, CAS 520-18-3
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Yellow needles from alcohol and water
Melting point
277 °C
Solubility
Soluble in hot alcohol, ether or alkalies
HS code
320415
Category
Flavonoids and polyphenols
Illustrative photo, yellow pigment powder in an open fibre drum in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Kaempferol?

Plain description, key identifiers and synonyms

Kaempferol is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment. It has a role as a geroprotector, an antibacterial agent, a plant metabolite, a human xenobiotic metabolite, a human urinary metabolite and a human blood serum metabolite. It is a member of flavonols, a tetrahydroxyflavone and a 7-hydroxyflavonol. It is a conjugate acid of a kaempferol oxoanion.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
CAS number
520-18-3 CAS number cross-checked
EC number
208-287-6
Molecular formula
C15H10O6
UNII
731P2LE49E
MDL number
MFCD00016938
INCI name
KAEMPFEROL
InChIKey
IYRMWMYZSQPJKC-UHFFFAOYSA-N
InChI
InChI=1S/C15H10O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,16-18,20H
SMILES (canonical and isomeric)
C1=CC(=CC=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O

Synonyms

  • Kaempherol
  • Robigenin
  • Rhamnolutein
  • Populnetin
  • Trifolitin
  • Indigo Yellow
  • Pelargidenolon
  • Rhamnolutin
  • Kempferol
  • Swartziol
  • 3,4',5,7-Tetrahydroxyflavone
  • Nimbecetin
  • 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one
  • Campherol
  • Kampferol
  • Kampherol
  • Kaemferol
  • 5,7,4'-Trihydroxyflavonol
  • Pelargidenolon 1497
  • 3,5,7-Trihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
  • 3,5,7-trihydroxy-2-(4-hydroxyphenyl)chromen-4-one
  • C.I. 75640
  • 4H-1-Benzopyran-4-one, 3,5,7-trihydroxy-2-(4-hydroxyphenyl)-
  • Flavone, 3,4',5,7-tetrahydroxy-
  • 3,5,7,4'-Tetrahydroxyflavone
Show all 37 synonyms
  • Kampcetin
  • Pelargidenon
  • Kempferol, Robigenin
  • Kaempferol (Standard)
  • 3'-Deoxyquercetin
  • CI 75640
  • isotein
  • kaempferal
  • Kaem
  • 3,4,5,7-Tetrahydroxyflavone
  • 4det
  • Robigenin (Standard)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Yellow needles from alcohol and waterexp.
Melting point
277 °Cexp.
Solubility
Soluble in hot alcohol, ether or alkaliesexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
286.24 g/molcalc.
Exact mass
286.0477 Dacalc.
LogP (octanol/water)
2.28calc.
Topological polar surface area
111.1 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc(-c2ccccc2)oc2ccccc12

O=c1cc(-c2ccccc2)oc2ccccc12

3 rings, 17 atoms, the Flavone ring system.

2,273 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H341Suspected of causing genetic defects.
Precautionary statements (10)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P318If exposed or concerned, get medical advice.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Kaempferol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 102 suppliers
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Where suppliers are based

102 suppliers in 14 countries

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Kaempferol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Antioxidants useful in cosmetics. (From table).

Flavone dye.

Cosmetic ingredient, INCI name KAEMPFEROL(antioxidant, skin conditioning - emollient)

Roles

  • animal metabolite
  • antibacterial agent
  • antimicrobial agent
  • eukaryotic metabolite
  • geroprotector
  • human blood serum metabolite
  • human metabolite
  • human urinary metabolite
  • human xenobiotic metabolite
  • mammalian metabolite
  • metabolite
  • pharmaceutical
  • plant metabolite
  • protective agent
  • xenobiotic metabolite

Functional uses

  • Antioxidant
  • Softener and conditioner

Cosmetic functions

  • Antioxidant
  • Skin conditioning - emollient

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Kaempferol is traded under.

HS 3204.15Indicative HS code

Vat dyes (including those usable in that state as pigments) and preparations based thereon

World exports in 2024
$435M
−7.3% vs 2023, imports $357M
2019 to 2024
Top exporters
  1. China60.2%
  2. Singapore10.7%
  3. India * partner reported8.7%
Top importers
  1. India * partner reported17.1%
  2. Turkey10.7%
  3. Singapore10.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Kaempferol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Kaempferol, based on the data on this page

What is Kaempferol?

Kaempferol is a tetrahydroxyflavone in which the four hydroxy groups are located at positions 3, 5, 7 and 4'. Acting as an antioxidant by reducing oxidative stress, it is currently under consideration as a possible cancer treatment.

What is the CAS number of Kaempferol?

The CAS registry number of Kaempferol is 520-18-3.

What is the molecular formula and weight of Kaempferol?

The molecular formula of Kaempferol is C15H10O6 and its molar mass is 286.24 g/mol.

What is Kaempferol used for?

Antioxidants useful in cosmetics. (From table). Flavone dye.

Is Kaempferol hazardous?

Kaempferol carries the GHS signal word "Danger". Main hazards: toxic if swallowed, suspected of causing genetic defects. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Kaempferol?

Kaempferol is usually classified under HS code 320415 (Vat dyes (including those usable in that state as pigments) and preparations based thereon). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Kaempferol?

CompoundList lists 102 suppliers of Kaempferol in China, United States, United Kingdom, Germany and 10 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Kaempferol?

Suppliers quote Kaempferol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Kaempferol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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