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Analgesics and anti-inflammatories

Flurbiprofen

Also known as Ansaid, Froben, Antadys

CAS 5104-49-4Formula C15H13FO2Molar mass 244.27 g/molEC 225-827-6
GHS signal word: Danger. Pictograms: Acute toxicity (severe), Harmful or irritant, Serious health hazard 155 suppliers listed Drug substance
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Flurbiprofen chemical structure, C15H13FO2, CAS 5104-49-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
5104-49-4
Formula
C15H13FO2
Molar mass
244.27 g/mol
EC number
225-827-6
HS code
291639
Category
Analgesics and anti-inflammatories

What is Flurbiprofen?

Plain description, key identifiers and synonyms

Flurbiprofen is a monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic, an antipyretic and an EC 1.14.99.1 (prostaglandin-endoperoxide synthase) inhibitor. It is a monocarboxylic acid and a fluorobiphenyl. It is functionally related to a propionic acid. It derives from a hydride of a biphenyl.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(3-fluoro-4-phenylphenyl)propanoic acid
CAS number
5104-49-4 CAS number cross-checkedOther or deprecated CAS: 51543-38-5
EC numbers
225-827-6, 257-262-6
Molecular formula
C15H13FO2
UNII
5GRO578KLP
MDL number
MFCD00079303
InChIKey
SYTBZMRGLBWNTM-UHFFFAOYSA-N
InChI
InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
SMILES (canonical and isomeric)
CC(C1=CC(=C(C=C1)C2=CC=CC=C2)F)C(=O)O

Synonyms

  • Ansaid
  • Froben
  • Antadys
  • 2-(3-fluoro-4-phenylphenyl)propanoic acid
  • 2-(2-fluorobiphenyl-4-yl)propanoic acid
  • Cebutid
  • Zepolas
  • Flubiprofen
  • Flurbiprofene
  • Flurbiprofeno
  • 3-Fluoro-4-phenylhydratropic acid
  • Flurbiprofenum
  • BTS 18322
  • 2-Fluoro-alpha-methyl-(1,1'-biphenyl)-4-acetic acid
  • (+-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
  • BTS 18,322
  • Fluriproben
  • (1,1'-Biphenyl)-4-acetic acid, 2-fluoro-alpha-methyl-, (+-)-
  • Froben Sr
  • Strefen
  • Novo Flurprofen
  • Nu Flurbiprofen
  • Apo Flurbiprofen
  • Rinol-STroche
  • ratio Flurbiprofen
Show all 35 synonyms
  • 2-Fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic acid
  • Antiphlamine Pain Relieving
  • (2RS)-2-(2-Fluorobiphenyl-4-yl)propanoic acid
  • Flurofen
  • Adfeed
  • Ocufen
  • 2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic acid
  • FP 70
  • Stayban
  • 2-(2-Fluoro-4-biphenylyl)propionic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
244.27 g/molcalc.
Exact mass
244.09 Dacalc.
LogP (octanol/water)
3.68calc.
Topological polar surface area
37.3 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
1calc.
Rotatable bonds
3calc.
Heavy atoms
18calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.13calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(-c2ccccc2)cc1

c1ccc(-c2ccccc2)cc1

2 rings, 12 atoms, the Biphenyl ring system.

32,228 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H301Toxic if swallowed.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (21)
  • P203Obtain, read and follow all safety instructions before use.
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P318If exposed or concerned, get medical advice.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Flurbiprofen suppliers

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All 155 suppliers
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Where suppliers are based

155 suppliers in 21 countries

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Flurbiprofen price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Analgesics
  • Anti-Inflammatory Agents, Non-Steroidal
  • Cyclooxygenase Inhibitors

Roles

  • analgesic
  • anti-HIV agent
  • anti-anaemic agent
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antibacterial agent
  • antimicrobial agent
  • antipyretic
  • antirheumatic drug
  • antiviral agent
  • enzyme inhibitor
  • hypoglycemic agent
  • non-narcotic analgesic
  • non-steroidal anti-inflammatory drug
  • ophthalmology drug
  • pharmaceutical

Pharmacology

Flurbiprofen is a Nonsteroidal Anti-inflammatory Drug. The mechanism of action of flurbiprofen is as a Cyclooxygenase Inhibitor.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Flurbiprofen is traded under.

HS 2916.39Indicative HS code

Aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…

World exports in 2024
$706M
−6.8% vs 2023, imports $714M
2019 to 2024
Top exporters
  1. China49.0%
  2. India * partner reported16.2%
  3. Germany13.2%
Top importers
  1. India * partner reported14.5%
  2. United States12.2%
  3. Germany8.6%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Flurbiprofen is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Flurbiprofen, based on the data on this page

What is Flurbiprofen?

Flurbiprofen is a monocarboxylic acid that is a 2-fluoro-[1,1'-biphenyl-4-yl] moiety linked to C-2 of propionic acid. A non-steroidal anti-inflammatory, analgesic and antipyretic, it is used as a pre-operative anti-miotic as well as orally for arthritis or dental pain.

What is the CAS number of Flurbiprofen?

The CAS registry number of Flurbiprofen is 5104-49-4. Other or deprecated CAS numbers: 51543-38-5.

What is the molecular formula and weight of Flurbiprofen?

The molecular formula of Flurbiprofen is C15H13FO2 and its molar mass is 244.27 g/mol.

What is Flurbiprofen used for?

Use classes: Pharmaceuticals.

Is Flurbiprofen hazardous?

Flurbiprofen carries the GHS signal word "Danger". Main hazards: toxic if swallowed, causes skin irritation, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Flurbiprofen?

Flurbiprofen is usually classified under HS code 291639 (Aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Flurbiprofen?

CompoundList lists 155 suppliers of Flurbiprofen in China, United States, India, United Kingdom and 17 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Flurbiprofen in India?

20 suppliers in India list Flurbiprofen on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Flurbiprofen?

Suppliers quote Flurbiprofen on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Flurbiprofen

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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