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Sweeteners

Isomalt

Also known as C-isomaltidex, BAY I 3930, INS NO.953

CAS 64519-82-0Formula C12H24O11Molar mass 344.31 g/molEC 613-617-0
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Isomalt chemical structure, C12H24O11, CAS 64519-82-0
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
64519-82-0
Formula
C12H24O11
Physical form
Crystals
Solubility
Soluble in water, very slightly soluble in ethanol.
HS code
294000
Category
Sweeteners
Illustrative photo, closed white HDPE bottles and amber jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Isomalt?

Plain description, key identifiers and synonyms

(2xi)-6-O-alpha-D-glucopyranosyl-D-arabino-hexitol is a glycosyl alditol consisting of alpha-D-glucopyranose and (2)-D-arabino-hexitol residues joined in sequence by a (11) glycosidic bond. It is functionally related to an alpha-D-glucose.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(3R,4R,5R)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,4,5-pentol
CAS number
64519-82-0 CAS number cross-checked
EC numbers
613-617-0, 908-700-6
Molecular formula
C12H24O11
MDL number
MFCD00083636, MFCD00190708
INCI name
ISOMALT
InChIKey
SERLAGPUMNYUCK-BLEZHGCXSA-N
InChI
InChI=1S/C12H24O11/c13-1-4(15)7(17)8(18)5(16)3-22-12-11(21)10(20)9(19)6(2-14)23-12/h4-21H,1-3H2/t4?,5-,6-,7-,8-,9-,10+,11-,12+/m1/s1
Canonical SMILES
OCC(O)C(O)C(O)C(O)COC1OC(CO)C(O)C(O)C1O
Isomeric SMILES
C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)OC[C@H]([C@H]([C@@H](C(CO)O)O)O)O)O)O)O)O

Synonyms

  • C-isomaltidex
  • BAY I 3930
  • INS NO.953
  • Isomalt (II)
  • Isomalt (mart.)
  • Isomalt (usp-rs)
  • Isomalt (ep monograph)
  • GalenIQ
  • C* PharmIsoMaltidex
  • Hydrogenated isomaltulose.
  • D-Arabino-hexitol, 6-o-alpha-d-glucopyranosyl-, (2xi)-
  • D-Arabino-hexitol, 6-o-alpha-d-glucopyranosyl-, (2.xi.)-
  • 6-o-alpha-d-glucopyranosyl-d-glucitol mixed with 1-o-alpha-d-glucopyranosyl-d-mannitol
  • 6-O-alpha-D-glucopyranosyl-D-glucitol--1-O-alpha-D-glucopyranosyl-D-mannitol--water (1/1/2)
  • (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentaol
  • (3R,4R,5R)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,4,5-pentol
  • D-Glucitol, 6-O-a-D-glucopyranosyl-, mixt. with1-O-a-D-glucopyranosyl-D-mannitolOTHER CA INDEX NAMES:D-Mannitol, 1-O-a-D-glucopyranosyl-, mixt. contg.
  • glucosylsorbitol
  • (2xi)-6-O-alpha-D-glucopyranosyl-D-arabino-hexitol
  • A4017F7C-EDDD-4444-9BE5-110558E41162
  • (3R,4R,5R)-6-{[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}hexane-1,2,3,4,5-pentol
  • (3R,4R,5R)-6-[[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy]hexane-1,2,3,4,5-pentaol
  • D-arabino-Hexitol, 6-O-alpha-D-
  • D-arabino-Hexitol, 6-O-alpha-D-glucopyranosyl-, (2epsilon)-
  • (3R,4R,5R)-6-(((2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,4,5-pentol
Show all 26 synonyms
  • (3R,4R,5R)-6-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydropyran-2-yl]oxyhexane-1,2,3,4,5-pentol

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Crystalsexp.
Taste
Pure sweet taste (sweetening power =0.45 relative to sucrose in about a 10% solution)exp.
Solubility
Soluble in water, very slightly soluble in ethanol.exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
344.31 g/molcalc.
Exact mass
344.1319 Dacalc.
LogP (octanol/water)
-5.76calc.
Topological polar surface area
200.5 Ųcalc.
Hydrogen bond donors
9calc.
Hydrogen bond acceptors
11calc.
Rotatable bonds
8calc.
Heavy atoms
23calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
9calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCOCC1

C1CCOCC1

1 ring, 6 atoms, the Tetrahydropyran ring system.

12,069 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Isomalt suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 11 suppliers
11 of 11 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

11 suppliers in 4 countries

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Isomalt price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Isomalt is a noncariogenic excipient used in a variety fo pharmaceutical preparations including tablets or capsules, coatings, sachets, suspensions, and in effervescent tablets. It can also be used in direct compression and wet granulation. In buccal applications such as chewable tablets it is commonly used because of its negligible negative heat of solution, mild sweetness and 'mouth feel'. It is also used widely in lozenges, sugar-free chewing gum, and hard-boiled candies, and as a sweetening agent in confectionery for diabetics.

Sugar substitute for most applications in confectionery.

Applications in the nonfood sector (e.g., surfactant synthesis and resin production) are known.

Use classes: Food additives, Cosmetics.

Cosmetic ingredient, INCI name ISOMALT(humectant)

Roles

  • additive
  • anti-inflammatory agent
  • excipient
  • filler
  • flavouring agent
  • food additive
  • food component
  • physiological role
  • plasticiser
  • sweetening agent

Functional uses

  • Anti-caking agent
  • Filler
  • Flavouring and nutrient
  • Humectant

Cosmetic functions

  • Humectant

How it is made

On catalytic hydrogenation (of isomaltulose), isomalt is obtained as an approximately equimolar mixture of both isomers. Industrially hydrogenation is carried out as a fixed-bed process in the presence of nickel catalysts. After hydrogenation and complete deionization, isomalt is obtained as an agglomerate of the two isomalt components by using a specially developed drying process.

Read more

The agglomerates consist of discrete crystallites of GPM (1-O-alpha-D-glucopyranosyl-D-mannitol) dihydrate, anhydrous GPM, and 1,6-GPS (6-O-alpha-D-glucopyranosyl-D-sorbitol) with a primary crystal-size distribution of < 1 um. In processing, agglomerates about 0.2-2 mm in size behave like homogeneous crystallites. The isomalt components have a high tendency to crystallize (low solubility at low temperature). An isomalt variant which is enriched in 1,6-GPS could be obtained by enhanced crystallization techniques. Isomalt is commercially available either as crystalline product or as a concentrated liquid solution.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Food additive

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Isomalt is traded under.

HS 2940.00Indicative HS code

Sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37…

World exports in 2024
$1.4B
−5.4% vs 2023, imports $1.42B
2019 to 2024
Top exporters
  1. Germany23.7%
  2. China20.6%
  3. United States11.5%
Top importers
  1. United States14.0%
  2. Japan7.4%
  3. Germany6.1%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Isomalt is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Isomalt, based on the data on this page

What is Isomalt?

(2xi)-6-O-alpha-D-glucopyranosyl-D-arabino-hexitol is a glycosyl alditol consisting of alpha-D-glucopyranose and (2)-D-arabino-hexitol residues joined in sequence by a (11) glycosidic bond. It is functionally related to an alpha-D-glucose.

What is the CAS number of Isomalt?

The CAS registry number of Isomalt is 64519-82-0.

What is the molecular formula and weight of Isomalt?

The molecular formula of Isomalt is C12H24O11 and its molar mass is 344.31 g/mol.

What is Isomalt used for?

Isomalt is a noncariogenic excipient used in a variety fo pharmaceutical preparations including tablets or capsules, coatings, sachets, suspensions, and in effervescent tablets. It can also be used in direct compression and wet granulation.

Is Isomalt hazardous?

No GHS hazard classification for Isomalt is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Isomalt?

Isomalt is usually classified under HS code 294000 (Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Isomalt?

CompoundList lists 11 suppliers of Isomalt in China, United States, Czech Republic and Netherlands. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Isomalt?

Suppliers quote Isomalt on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Isomalt

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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