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Sweeteners

Lactitol

Also known as 4-O-beta-D-Galactopyranosyl-D-glucitol, Importal, D-lactitol

CAS 585-86-4Formula C12H24O11Molar mass 344.31 g/molEC 209-566-5
21 suppliers listed
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Lactitol chemical structure, C12H24O11, CAS 585-86-4
2D chemical structure

Key facts

What buyers check first

All properties
Appearance
Crystals from absolute ethanol
Melting point
146 °C
Solubility
In water, 57.2 g/100 g at 20 °C . With increasing temperature the solubility rises consi…
HS code
294000
Category
Sweeteners
Illustrative photo, assorted laboratory chemical bottles and jars on a laboratory bench
Typical packagingIllustrative packaging image, not the actual product

What is Lactitol?

Plain description, key identifiers and synonyms

Lactitol is a glycosyl alditol consisting of beta-D-galactopyranose and D-glucitol joined by a 14 glycosidic bond. It is used as a laxative, as an excipient, and as replacement bulk sweetener in some low-calorie foods. It has a role as a laxative, an excipient and a cathartic.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol
CAS number
585-86-4 CAS number cross-checked
EC number
209-566-5
Molecular formula
C12H24O11
UNII
L2B0WJF7ZY
MDL number
MFCD00079407
INCI name
LACTITOL
InChIKey
VQHSOMBJVWLPSR-JVCRWLNRSA-N
InChI
InChI=1S/C12H24O11/c13-1-4(16)7(18)11(5(17)2-14)23-12-10(21)9(20)8(19)6(3-15)22-12/h4-21H,1-3H2/t4-,5+,6+,7+,8-,9-,10+,11+,12-/m0/s1
Canonical SMILES
OCC(O)C(O)C(OC1OC(CO)C(O)C(O)C1O)C(O)CO
Isomeric SMILES
C([C@@H]1[C@@H]([C@@H]([C@H]([C@@H](O1)O[C@H]([C@@H](CO)O)[C@@H]([C@H](CO)O)O)O)O)O)O

Synonyms

  • 4-O-beta-D-Galactopyranosyl-D-glucitol
  • Importal
  • D-lactitol
  • lactositol
  • Lactosit
  • Miruhen
  • lactitolum
  • lactobiosit
  • Lactitol acm 50
  • Lactitol anhydrous
  • Lacty (saccharide)
  • Milchen
  • Lactit
  • Finlac dc
  • pizensy
  • INS NO.966
  • Neda Lactiv Importal
  • (2S,3R,4R,5R)-4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl)oxyhexane-1,2,3,5,6-pentol
  • (2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-methylol-tetrahydropyran-2-yl]oxyhexane-1,2,3,5,6-pentol
  • GlyTouCan:G26039ES
  • (2S,3R,4S,5R,6R)-2-((2R,3S,4S,5R)-4,5-dihydroxy-2,5-bis(hydroxymethyl)oxolan-3-yl)oxy-6-(hydroxymethyl)oxane-3,4,5-triol
  • Lacitol
  • Importal (TN)
  • (2S,3R,4R,5R)-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexane-1,2,3,5,6-pentaol
  • (2S,3R,4R,5R)-4-[(2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxyhexane-1,2,3,5,6-pentol
Show all 33 synonyms
  • lactite
  • D-Glucitol, 4-O-beta-D-galactopyranosyl-
  • Emportal
  • Oponaf
  • Floralac
  • Portolac
  • Pizensy (TN)
  • Lactitol (NF/INN)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Crystals from absolute ethanolexp.
Taste
30-40% of that of sucrose. The taste is sweet and cleanexp.
Melting point
146 °Cexp.
Solubility
In water, 57.2 g/100 g at 20 °C . With increasing temperature the solubility rises considerablyexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
344.31 g/molcalc.
Exact mass
344.1319 Dacalc.
LogP (octanol/water)
-5.76calc.
Topological polar surface area
200.5 Ųcalc.
Hydrogen bond donors
9calc.
Hydrogen bond acceptors
11calc.
Rotatable bonds
8calc.
Heavy atoms
23calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
9calc.
Lipinski rule of five
Fails (2 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCOCC1

C1CCOCC1

1 ring, 6 atoms, the Tetrahydropyran ring system.

12,069 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS classification
Hazard pictograms

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lactitol suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 21 suppliers
21 of 21 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

21 suppliers in 5 countries

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Lactitol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Lactitol is used as a noncariogenic replacement for sucrose. It is also used as a diluent in solid dosage forms. A direct-compression form is available, as is a direct-compression blend of lactose and lactitol.

Sweetener in food.

Use classes: Food additives, Cosmetics.

Cosmetic ingredient, INCI name LACTITOL(humectant, skin conditioning)

Pharmacological actions

  • Cathartics
  • Sweetening Agents

Roles

  • additive
  • biophysical role
  • cathartic
  • excipient
  • filler
  • laxative
  • pharmaceutical

Functional uses

  • Flavouring and nutrient
  • Humectant
  • Softener and conditioner

Cosmetic functions

  • Humectant
  • Skin conditioning

Pharmacology

Lactitol is an Osmotic Laxative. The mechanism of action of lactitol is as an Osmotic Activity. The physiologic effect of lactitol is by means of Stimulation Small Intestine Fluid/Electrolyte Secretion.

How it is made

Lactitol ... is formed from lactose, which is hydrogenated in the presence of Raney-Nickel catalyst. After sedimentation (to settle the catalyst) the solutions is filtered, purified, concentrated and crystallized.

For industrial production, an aqueous lactose solution (30-50 wt%) is hydrogenated at temperatures between 70 and 30 °C and a hydrogen pressure of 30-75 bar. Raney nickel is used as catalyst. After filtration, the material is subjected to ion exchange and concentrated by evaporation. Depending on the crystallization conditions, in particular temperature, lactitol is obtained as anhydrous substance, mono-, or dihydrate. The anhydrous form is formed at higher temperatures.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Food additive

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lactitol is traded under.

HS 2940.00Indicative HS code

Sugar ethers, sugar acetals and sugar esters, and their salts, other than the products of heading 29.37…

World exports in 2024
$1.4B
−5.4% vs 2023, imports $1.42B
2019 to 2024
Top exporters
  1. Germany23.7%
  2. China20.6%
  3. United States11.5%
Top importers
  1. United States14.0%
  2. Japan7.4%
  3. Germany6.1%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Lactitol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lactitol, based on the data on this page

What is Lactitol?

Lactitol is a glycosyl alditol consisting of beta-D-galactopyranose and D-glucitol joined by a 14 glycosidic bond. It is used as a laxative, as an excipient, and as replacement bulk sweetener in some low-calorie foods. It has a role as a laxative, an excipient and a cathartic.

What is the CAS number of Lactitol?

The CAS registry number of Lactitol is 585-86-4.

What is the molecular formula and weight of Lactitol?

The molecular formula of Lactitol is C12H24O11 and its molar mass is 344.31 g/mol.

What is Lactitol used for?

Lactitol is used as a noncariogenic replacement for sucrose. It is also used as a diluent in solid dosage forms. A direct-compression form is available, as is a direct-compression blend of lactose and lactitol. Sweetener in food. Use classes: Food additives, Cosmetics.

Is Lactitol hazardous?

No GHS hazard classification for Lactitol is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Lactitol?

Lactitol is usually classified under HS code 294000 (Sugars, chemically pure, other than sucrose, lactose, maltose, glucose and fructose…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lactitol?

CompoundList lists 21 suppliers of Lactitol in China, India, United States, Thailand and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Lactitol in India?

5 suppliers in India list Lactitol on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Lactitol?

Suppliers quote Lactitol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lactitol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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