Levallorphan
Also known as Naloxiphan, Levallorphane, 17-Allylmorphinan-3-ol
Key facts
What buyers check first
- Appearance
- Crystals from dilute ethanol
- Melting point
- 180 to 182 °C
- Solubility
- WHITE OR PRACTICALLY WHITE CRYSTALLINE POWDER, 1 G SOL IN ABOUT 20 ML WATER, PRACTICALLY…
- HS code
- 293399
- Category
- Heterocyclic building blocks

What is Levallorphan?
Plain description, key identifiers and synonyms
Levallorphan is a morphinane alkaloid.
Levallorphan is an opioid medication.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (1R,9R,10R)-17-prop-2-enyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
- CAS number
- 152-02-3 CAS number cross-checked
- EC number
- 205-799-1
- Molecular formula
- C19H25NO
- UNII
- 353613BU4U
- InChIKey
- OZYUPQUCAUTOBP-QXAKKESOSA-N
- InChI
- InChI=1S/C19H25NO/c1-2-10-20-11-9-19-8-4-3-5-16(19)18(20)12-14-6-7-15(21)13-17(14)19/h2,6-7,13,16,18,21H,1,3-5,8-12H2/t16-,18+,19+/m0/s1
- Canonical SMILES
- C=CCN1CCC23CCCCC2C1Cc1ccc(O)cc13
- Isomeric SMILES
- C=CCN1CC[C@]23CCCC[C@H]2[C@H]1CC4=C3C=C(C=C4)O
Synonyms
- Naloxiphan
- Levallorphane
- 17-Allylmorphinan-3-ol
- Levalorfano
- Levallorphanum
- Levallofano
- N-Allyl-3-hydroxymorphinan
- L-N-Allyl-3-hydroxymorphinan
- (-)-3-Hydroxy-N-allylmorphinan
- Levo-3-hydroxy-N-allyl morphinan
- Morphinan-3-ol, 17-allyl-
- Ro-1-7700
- Morphinan, 17-allyl-3-hydroxy-
- (1R,9R,10R)-17-prop-2-enyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
- (1R,9R,10R)-17-(prop-2-en-1-yl)-17-azatetracyclo[7.5.3.0^{1,10}.0^{2,7}]heptadeca-2(7),3,5-trien-4-ol
- (1R,9R,10R)-17-(prop-2-en-1-yl)-17-azatetracyclo(7.5.3.0^(1,10).0^(2,7))heptadeca-2(7),3,5-trien-4-ol
- (1R,9R,10R)-17-prop-2-enyl-17-azatetracyclo(7.5.3.01,10.02,7)heptadeca-2(7),3,5-trien-4-ol
- Morphinan-3-ol, 17-(2-propenyl)-
- MCL 113, N-Allyl-3-hydroxymorphinan
- 17-prop-2-en-1-ylmorphinan-3-ol
- Morphinan-3-ol, 17-allyl-, (-)-
- (a^?-17-allylmorphinan-3-ol
- (levallorphan)17-allyl-(1R,9R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol
- 17-allyl-(1R,9R)-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol( Levallorphan)
- 17-allyl-17-azatetracyclo[7.5.3.01,10.02,7]heptadeca-2(7),3,5-trien-4-ol (Levallorphan)
Show all 26 synonymsShow fewer synonyms
- 17-(prop-2-en-1-yl)morphinan-3-ol
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
| Appearance | Crystals from dilute ethanolexp.Measured value |
|---|---|
| Melting point | 180 to 182 °Cexp.Measured value |
| Solubility | WHITE OR PRACTICALLY WHITE CRYSTALLINE POWDER, 1 G SOL IN ABOUT 20 ML WATER, PRACTICALLY INSOL IN ETHER, INSOL IN CHLOROFORM, 1 G SOL IN ABOUT 60 ML ALCOHOL /TARTRATE/exp.Measured value |
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 283.42 g/molcalc.Computed value |
|---|---|
| Exact mass | 283.1936 Dacalc.Computed value |
| LogP (octanol/water) | 3.64calc.Computed value |
| Topological polar surface area | 23.47 Ųcalc.Computed value |
| Hydrogen bond donors | 1calc.Computed value |
| Hydrogen bond acceptors | 2calc.Computed value |
| Rotatable bonds | 2calc.Computed value |
| Heavy atoms | 21calc.Computed value |
| Rings | 4calc.Computed value |
| Aromatic rings | 1calc.Computed value |
| Fraction sp3 carbons | 0.58calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Levallorphan suppliers
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- Price on request
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Where suppliers are based
1 supplier in 1 country
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Levallorphan price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
In treatment of narcotic-induced resp depression (tartrate).
Veterinary medication:.
Use classes: Pharmaceuticals.
Industries and functions
Pharmacological actions
- Narcotic Antagonists
How it is made
Prepn from 3-hydroxy-n-methylmorphinan: schnider, grussner, helv chim acta 34, 2211 (1951). Alternate route: hellerbach et al, ibid 39, 429 (1956).
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Levallorphan is traded under.
Heterocyclic compounds with nitrogen hetero-atom(s) only, other
- Slovenia31.7%
- Italy24.2%
- United States5.0%
* Partner reported figures, a lower bound.
The HS code shown for Levallorphan is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Levallorphan, based on the data on this page
What is Levallorphan?
What is the CAS number of Levallorphan?
What is the molecular formula and weight of Levallorphan?
What is Levallorphan used for?
Is Levallorphan hazardous?
What is the HS code of Levallorphan?
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What is the price of Levallorphan?
Guides for buyers
Practical guides that help when you source, ship or handle Levallorphan
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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