CompoundList
Sign in
Central nervous system drugs

Lisuride

Also known as Lysuride, Lisurida, Lisuridum

CAS 18016-80-3Formula C20H26N4OMolar mass 338.46 g/molEC 241-925-1
GHS signal word: Danger. Pictograms: Acute toxicity (severe) 8 suppliers listed
Get quotes Compare 8 suppliers
Lisuride chemical structure, C20H26N4O, CAS 18016-80-3
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
18016-80-3
Formula
C20H26N4O
Molar mass
338.46 g/mol
EC number
241-925-1
HS code
293969
Category
Central nervous system drugs

What is Lisuride?

Plain description, key identifiers and synonyms

Lisuride is a monocarboxylic acid amide. It has a role as a serotonergic agonist, an antiparkinson drug, a dopamine agonist and an antidyskinesia agent. It derives from a hydride of an ergoline.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea
CAS number
18016-80-3 CAS number cross-checkedOther or deprecated CAS: 140387-89-9
EC number
241-925-1
Molecular formula
C20H26N4O
UNII
E0QN3D755O
InChIKey
BKRGVLQUQGGVSM-KBXCAEBGSA-N
InChI
InChI=1S/C20H26N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,10-11,14,18,21H,4-5,9,12H2,1-3H3,(H,22,25)/t14-,18+/m0/s1
Canonical SMILES
CCN(CC)C(=O)NC1C=C2c3cccc4[nH]cc(c34)CC2N(C)C1
Isomeric SMILES
CCN(CC)C(=O)N[C@@H]1CN([C@@H]2CC3=CNC4=CC=CC(=C34)C2=C1)C

Synonyms

  • Lysuride
  • Lisurida
  • Lisuridum
  • Dopergin
  • N'-((8alpha)-9,10-Didehydro-6-methylergolin-8-yl)-N,N-diethylurea
  • Methylergol Carbamide
  • Lysurid
  • Urea, N'-((8alpha)-9,10-didehydro-6-methylergolin-8-yl)-N,N-diethyl-
  • 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(16),2,9,12,14-pentaen-4-yl]urea
  • Mesylate, Lisuride
  • 3,3-diethyl-1-((4S,7R)-6-methyl-6,11-diazatetracyclo(7.6.1.0^(2,7).0^(12,16))hexadeca-1(16),2,9,12,14-pentaen-4-yl)urea
  • Revanil 200
  • Carbamide, Methylergol
  • Hydrochloride, Lisuride
  • Lisuride (INN)
  • Lisuride (S)(-)
  • 1,1-diethyl-3-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea
  • 3-[(6aR,9S)-7-methyl-6,6a,8,9-tetrahydro-4H-indolo[4,3-fg]quinolin-9-yl]-1,1-diethylurea
  • 3,3-diethyl-1-[(4S,7R)-6-methyl-6,11-diazatetracyclo[7.6.1.0^{2,7}.0^{12,16}]hexadeca-1(15),2,9,12(16),13-pentaen-4-yl]urea
  • N,N-diethyl-N'-[(8alpha)-6-methyl-9,10-didehydroergolin-8-yl]urea
  • R(+)-Lisuride hydrogen maleate
  • DL-Lisuride
  • 18016-80-3 (free base)
  • (+)-lisuride
  • lisuride, (S)
Show all 29 synonyms
  • LISURIDE, Lysuride
  • 3-(9,10-Didehydro-6-methylergolin-8alpha-yl)-1,1-diethylurea
  • N,N-Diethyl-N'-(6-methyl-9,10-didehydroergolin-8-yl)urea
  • Urea, N'-[(8a)-9,10-didehydro-6-methylergolin-8-yl]-N,N-diethyl-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
338.46 g/molcalc.
Exact mass
338.2107 Dacalc.
LogP (octanol/water)
2.84calc.
Topological polar surface area
51.37 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
25calc.
Rings
4calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.45calc.
Formal charge
0calc.
Stereocentres
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1=C2c3cccc4[nH]cc(c34)CC2NCC1

C1=C2c3cccc4[nH]cc(c34)CC2NCC1

4 rings, 16 atoms, the 9,10-Ergolene ring system.

145 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS06: Acute toxicity (severe)
Acute toxicity (severe)

Hazard statements

  • H300Fatal if swallowed.
  • H310Fatal in contact with skin.
  • H330Fatal if inhaled.
Precautionary statements (18)
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P262Do not get in eyes, on skin, or on clothing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P284In case of inadequate ventilation wear respiratory protection.
  • P301 + P316If swallowed: Get emergency medical help immediately.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P316Get emergency medical help immediately.
  • P320Specific treatment is urgent (see supplemental first aid instructions on the label).
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P361 + P364Take off immediately all contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lisuride suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 5 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Lisuride price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Industries and functions

Pharmacological actions

  • Antiparkinson Agents
  • Dopamine Agonists
  • Serotonin Receptor Agonists

Roles

  • antidyskinesia agent
  • antiparkinson drug
  • dopamine agonist
  • dopaminergic agent
  • neurotransmitter agent
  • pharmaceutical
  • serotonergic agonist
  • serotonergic drug

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lisuride is traded under.

HS 2939.69Indicative HS code

Alkaloids of rye ergot and their derivatives, salts thereof, other

World exports in 2024
$66.7M
+1.1% vs 2023, imports $78M
2019 to 2024
Top exporters
  1. Czech Republic62.5%
  2. Italy14.4%
  3. United States3.7%
Top importers
  1. Japan25.8%
  2. China11.3%
  3. United States7.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Lisuride is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lisuride, based on the data on this page

What is Lisuride?

Lisuride is a monocarboxylic acid amide. It has a role as a serotonergic agonist, an antiparkinson drug, a dopamine agonist and an antidyskinesia agent. It derives from a hydride of an ergoline.

What is the CAS number of Lisuride?

The CAS registry number of Lisuride is 18016-80-3. Other or deprecated CAS numbers: 140387-89-9.

What is the molecular formula and weight of Lisuride?

The molecular formula of Lisuride is C20H26N4O and its molar mass is 338.46 g/mol.

What is Lisuride used for?

Known uses and roles of Lisuride include cns agents in pharmaceuticals, antidyskinesia agent, antiparkinson drug, dopamine agonist, dopaminergic agent and 7 more.

Is Lisuride hazardous?

Lisuride carries the GHS signal word "Danger". Main hazards: fatal if swallowed, fatal in contact with skin, fatal if inhaled. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lisuride?

Lisuride is usually classified under HS code 293969 (Alkaloids of rye ergot and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lisuride?

CompoundList lists 8 suppliers of Lisuride in China, Spain, Japan, Netherlands and 1 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Lisuride?

Suppliers quote Lisuride on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lisuride

Get quotes for Lisuride

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Lisuride
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Lisuride with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/lisuride-18016-80-3" title="Lisuride structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Central nervous system drugs or HS code 293969

8 suppliers
Free quotes, contact stays private
Get quotes