CompoundList
Sign in
Heterocyclic building blocks

Loline

Also known as Festucine, (+)-Loline, (1R,3S,7S,8R)-N-methyl-2-oxa-6-azatricyclo[4.2.1.03,7]nonan-8-amine

CAS 25161-91-5Formula C8H14N2OMolar mass 154.21 g/mol
Get quotes Safety data
Loline chemical structure, C8H14N2O, CAS 25161-91-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
25161-91-5
Formula
C8H14N2O
Molar mass
154.21 g/mol
HS code
293499
Category
Heterocyclic building blocks

What is Loline?

Plain description, key identifiers and synonyms

Loline is a loline alkaloid with formula C8H14N2O. It is a loline alkaloid and a secondary amino compound.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1R,3S,7S,8R)-N-methyl-2-oxa-6-azatricyclo[4.2.1.03,7]nonan-8-amine
CAS number
25161-91-5
Molecular formula
C8H14N2O
UNII
IC997T2WZ9
InChIKey
OPMNROCQHKJDAQ-FKSUSPILSA-N
InChI
InChI=1S/C8H14N2O/c1-9-7-6-4-10-3-2-5(11-6)8(7)10/h5-9H,2-4H2,1H3/t5-,6+,7-,8+/m0/s1
Canonical SMILES
CNC1C2CN3CCC(O2)C13
Isomeric SMILES
CN[C@H]1[C@H]2CN3[C@@H]1[C@@H](O2)CC3

Synonyms

  • Festucine
  • (+)-Loline
  • (1R,3S,7S,8R)-N-methyl-2-oxa-6-azatricyclo[4.2.1.03,7]nonan-8-amine
  • 2,4-Methano-4H-furo(3,2-b)pyrrol-3-amine, hexahydro-N-methyl-, (2R,3R,3aS,4S,6aS)-
  • (1R,3S,7S,8R)-N-methyl-2-oxa-6-azatricyclo(4.2.1.03,7)nonan-8-amine
  • 2,4-Methano-4H-furo(3,2-b)pyrrol-3-amine, hexahydro-N-methyl-, (2R,3R,3aS,6aS)-
  • (2R,3R,3aS,4S,6aS)-Hexahydro-N-methyl-2,4-methano-4H-furo[3,2-b]pyrrol-3-amine
  • (1S,6R,7R,7aS)-N-Methylhexahydro-1H-1,6-epoxypyrrolizin-7-amine
  • lolina
  • (2R,3R,3as,4S,6as)-hexahydro-N-methyl-2,4-methano-4H-furo(3,2-b)pyrrol-3-amine
  • Methyl-N-depropionyldecorticasine
  • 2,4-Methano-4H-furo(3,2-b)pyrrole, hexahydro-3-(methylamino)-
  • (1R,3S,7S,8R)-N-methyl-2-oxa-6-azatricyclo[4.2.1.0?,?]nonan-8-amine
  • 2,4-Methano-4H-furo(3,2-b)pyrrol-3-amine, hexahydro-N-methyl-, (2R-(2-alpha,3-alpha,3a-beta,4-alpha,6a-beta))-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
154.21 g/molcalc.
Exact mass
154.1106 Dacalc.
LogP (octanol/water)
-0.57calc.
Topological polar surface area
24.5 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
11calc.
Rings
3calc.
Aromatic rings
0calc.
Fraction sp3 carbons
1calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CN2CC3CC2C1O3

C1CN2CC3CC2C1O3

3 rings, 9 atoms.

18 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Loline suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

No supplier listings yet

Post one free request and suppliers who make or trade Loline can send you quotes. Your contact details stay private until you accept a quote.

Request quotesSell this chemical

Loline price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Loline is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Loline is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Loline, based on the data on this page

What is Loline?

Loline is a loline alkaloid with formula C8H14N2O. It is a loline alkaloid and a secondary amino compound.

What is the CAS number of Loline?

The CAS registry number of Loline is 25161-91-5.

What is the molecular formula and weight of Loline?

The molecular formula of Loline is C8H14N2O and its molar mass is 154.21 g/mol.

What is Loline used for?

Known uses and roles of Loline include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Loline hazardous?

No GHS hazard classification for Loline is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Loline?

Loline is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Loline?

Post a free request on CompoundList and suppliers of Loline will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Loline?

Suppliers quote Loline on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Loline

Get quotes for Loline

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Loline
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Loline with a 3D view, its CAS number and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/loline-25161-91-5" title="Loline structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Heterocyclic building blocks or HS code 293499

Price on request
Free quotes, contact stays private
Get quotes