CompoundList
Sign in
Screening compounds

Lonidamine

Also known as 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid, Diclondazolic acid, Doridamina

CAS 50264-69-2Formula C15H10Cl2N2O2Molar mass 321.16 g/molEC 256-510-0
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 43 suppliers listed
Get quotes Compare 43 suppliers
Lonidamine chemical structure, C15H10Cl2N2O2, CAS 50264-69-2
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
50264-69-2
Formula
C15H10Cl2N2O2
Molar mass
321.16 g/mol
EC number
256-510-0
HS code
293399
Category
Screening compounds

What is Lonidamine?

Plain description, key identifiers and synonyms

Lonidamine is a member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively. It has a role as an antispermatogenic agent, a geroprotector, an antineoplastic agent and an EC 2.7.1.1 (hexokinase) inhibitor. It is a dichlorobenzene, a monocarboxylic acid and a member of indazoles.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid
CAS number
50264-69-2 CAS number cross-checked
EC number
256-510-0
Molecular formula
C15H10Cl2N2O2
UNII
U78804BIDR
MDL number
MFCD00866285
InChIKey
WDRYRZXSPDWGEB-UHFFFAOYSA-N
InChI
InChI=1S/C15H10Cl2N2O2/c16-10-6-5-9(12(17)7-10)8-19-13-4-2-1-3-11(13)14(18-19)15(20)21/h1-7H,8H2,(H,20,21)
SMILES (canonical and isomeric)
C1=CC=C2C(=C1)C(=NN2CC3=C(C=C(C=C3)Cl)Cl)C(=O)O

Synonyms

  • 1-(2,4-Dichlorobenzyl)-1H-indazole-3-carboxylic acid
  • Diclondazolic acid
  • Doridamina
  • Lonidamina
  • Lonidaminum
  • AF 1890
  • 1-[(2,4-dichlorophenyl)methyl]indazole-3-carboxylic acid
  • 1-(2,4-Dichlorbenzyl)-indazole-3-carboxylic acid
  • 1-(2,4-dichlorobenzyl)indazole-3-carboxylic acid
  • 1H-Indazole-3-carboxylic acid, 1-((2,4-dichlorophenyl)methyl)-
  • 1H-Indazole-3-carboxylic acid, 1-[(2,4-dichlorophenyl)methyl]-
  • 1-((2,4-dichlorophenyl)methyl)indazole-3-carboxylic acid
  • DICA
  • 1-[(2,4-dichlorophenyl)methyl]-1H-indazole-3-carboxylic acid
  • Lonidamin
  • Lonidamine (INN)
  • AF-1890, Diclondazolic Acid, DICA
  • Doridamina (TN)
  • Dichlondazolic acid
  • 1-((2,4-Dichlorophenyl)methyl)-1H-indazole-3-carboxylic acid
  • Lonidamine?
  • Lonidamine (Standard)
  • Tocris-1646
  • Lonidamine (AF 1890)
  • 1H-Indazole-3-carboxylic acid, 1-(2,4-dichlorobenzyl)-
Show all 29 synonyms
  • 1H-Indazole-3-carboxylicacid, 1-[(2,4-dichlorophenyl)methyl]-
  • Sdccgsbi-0050696.p003
  • Lonidamine, mitochondrial hexokinase inhibitor
  • Lonidamine, 99%, mitochondrial hexokinase inhibitor

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
321.16 g/molcalc.
Exact mass
320.0119 Dacalc.
LogP (octanol/water)
4.09calc.
Topological polar surface area
55.12 Ųcalc.
Hydrogen bond donors
1calc.
Hydrogen bond acceptors
2calc.
Rotatable bonds
3calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(Cn2ncc3ccccc32)cc1

c1ccc(Cn2ncc3ccccc32)cc1

3 rings, 16 atoms, the 1-Benzyl-1H-indazole ring system.

286 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H351Suspected of causing cancer.
  • H360May damage fertility or the unborn child.
Precautionary statements (9)
  • P203Obtain, read and follow all safety instructions before use.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lonidamine suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 43 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

43 suppliers in 7 countries

Send one request to many suppliers

Choose up to 10 suppliers or let us match your request. Compare quotes side by side, free.

Choose suppliersPost a request

Lonidamine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

Get latest price

Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antineoplastic Agents
  • Antispermatogenic Agents
  • Radiation-Sensitizing Agents
  • Trypanocidal Agents

Roles

  • antineoplastic agent
  • antispermatogenic agent
  • enzyme inhibitor
  • geroprotector
  • lipid kinase inhibitor
  • pharmaceutical
  • protective agent

Pharmacology

Lonidamine is an indazole carboxylic acid derivative that exhibits radiosensitizing and antiparasitic effects and interferes with the multidrug resistance mechanism.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lonidamine is traded under.

HS 2933.99Indicative HS code

Heterocyclic compounds with nitrogen hetero-atom(s) only, other

World exports in 2024
$12.1B
−31.0% vs 2023, imports $28.8B
2019 to 2024
Top exporters
  1. China30.5%
  2. India * partner reported16.3%
  3. Ireland9.0%
Top importers
  1. Slovenia31.7%
  2. Italy24.2%
  3. United States5.0%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lonidamine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lonidamine, based on the data on this page

What is Lonidamine?

Lonidamine is a member of the class of indazoles that is 1H-indazole that is substituted at positions 1 and 3 by 2,4-dichlorobenzyl and carboxy groups, respectively. It has a role as an antispermatogenic agent, a geroprotector, an antineoplastic agent and an EC 2.7.1.1 (hexokinase) inhibitor.

What is the CAS number of Lonidamine?

The CAS registry number of Lonidamine is 50264-69-2.

What is the molecular formula and weight of Lonidamine?

The molecular formula of Lonidamine is C15H10Cl2N2O2 and its molar mass is 321.16 g/mol.

What is Lonidamine used for?

Known uses and roles of Lonidamine include building blocks in research and laboratory, screening compounds in research and laboratory, antineoplastic agent, antispermatogenic agent, enzyme inhibitor and 8 more.

Is Lonidamine hazardous?

Lonidamine carries the GHS signal word "Danger". Main hazards: harmful if swallowed, suspected of causing cancer, may damage fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lonidamine?

Lonidamine is usually classified under HS code 293399 (Heterocyclic compounds with nitrogen hetero-atom(s) only, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Lonidamine?

CompoundList lists 43 suppliers of Lonidamine in China, United States, United Kingdom, Germany and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Lonidamine?

Suppliers quote Lonidamine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Lonidamine

Get quotes for Lonidamine

Post one free request with your grade, quantity and destination. Matching suppliers send quotes you can compare side by side.
Post a request Sell Lonidamine
Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
Embed this structure on your websiteShow code

Paste this code into your page to show the 2D structure of Lonidamine with a 3D view, its CAS number where known and a link back to this page. Free to use with the link kept.

<iframe src="https://www.compoundlist.com/embed/structure/lonidamine-50264-69-2" title="Lonidamine structure on CompoundList" width="360" height="420" style="border:1px solid #E7E2DA;border-radius:12px;max-width:100%" loading="lazy" referrerpolicy="strict-origin-when-cross-origin"></iframe>
Preview the embed

Explore more in Screening compounds or HS code 293399

43 suppliers
Free quotes, contact stays private
Get quotes