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Central nervous system drugs

Lorazepam

Also known as Ativan, Temesta, Loraz

CAS 846-49-1Formula C15H10Cl2N2O2Molar mass 321.16 g/molEC 212-687-6
GHS signal word: Warning. Pictograms: Serious health hazard Prohibited, not for trade Drug substance
Why it is not for trade
Lorazepam chemical structure, C15H10Cl2N2O2, CAS 846-49-1
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
846-49-1
Formula
C15H10Cl2N2O2
Molar mass
321.16 g/mol
EC number
212-687-6
HS code
293391
Category
Central nervous system drugs

What is Lorazepam?

Plain description, key identifiers and synonyms

Lorazepam is a benzodiazepine.

Lorazepam is a benzodiazepine medication.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
CAS number
846-49-1 CAS number cross-checked
EC number
212-687-6
Molecular formula
C15H10Cl2N2O2
UNII
O26FZP769L
InChIKey
DIWRORZWFLOCLC-UHFFFAOYSA-N
InChI
InChI=1S/C15H10Cl2N2O2/c16-8-5-6-12-10(7-8)13(19-15(21)14(20)18-12)9-3-1-2-4-11(9)17/h1-7,15,21H,(H,18,20)
SMILES (canonical and isomeric)
C1=CC=C(C(=C1)C2=NC(C(=O)NC3=C2C=C(C=C3)Cl)O)Cl

Synonyms

  • Ativan
  • Temesta
  • Loraz
  • Wypax
  • Almazine
  • Anxiedin
  • Lorabenz
  • Orfidal
  • Lorazepam Intensol
  • Wy-4036
  • Lorazepamum
  • Wy 4036
  • 7-chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-1,4-benzodiazepin-2-one
  • Lorazepam preservative free
  • Lorazepam civ
  • 2H-1,4-Benzodiazepin-2-one, 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-
  • 7-Chloro-5-(o-chlorophenyl)-1,3-dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one
  • Loreev xr
  • Durazolam
  • Apo Lorazepam
  • Orfidal Wyeth
  • Novo Lorazem
  • Wyeth, Orfidal
  • 7-chloro-5-(2-chlorophenyl)-3-hydroxy-2,3-dihydro-1H-1,4-benzodiazepin-2-one
  • Medical, Lorazepam
Show all 38 synonyms
  • Lorazepam ratiopharm
  • Lorazepam neuraxpharm
  • Von Ct, Lorazep
  • Abbloraz
  • (3RS)-7-Chloro-5-(2-chlorophenyl)-3-hydroxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one
  • 7-Chloro-5-(2-chlorophenyl)-1, 3-Dihydro-3-Hydroxy-1,4-Benzodiazepin-2-one
  • (+-)-Lorazepam
  • o-Chloroxazepam
  • o-Chlorooxazepam
  • Emotival
  • Tavor
  • Delormetazepam
  • Norlormetazepam

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
321.16 g/molcalc.
Exact mass
320.0119 Dacalc.
LogP (octanol/water)
3.1calc.
Topological polar surface area
61.69 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
1calc.
Heavy atoms
21calc.
Rings
3calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.07calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CN=C(c2ccccc2)c2ccccc2N1

O=C1CN=C(c2ccccc2)c2ccccc2N1

3 rings, 18 atoms, the RO-05-2921 ring system.

540 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H361Suspected of damaging fertility or the unborn child.
Precautionary statements (5)
  • P203Obtain, read and follow all safety instructions before use.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P318If exposed or concerned, get medical advice.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Lorazepam suppliers

Trading restrictions apply to this substance

Psychotropic substance

Lorazepam is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)

Our policy on controlled substances

Lorazepam price

Indicative price range per kg from live supplier offers

Prices are not shown for prohibited substances.

Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Industries and functions

Pharmacological actions

  • Anti-Anxiety Agents
  • Anticonvulsants
  • Antiemetics
  • GABA Modulators
  • Hypnotics and Sedatives

Roles

  • analgesic
  • anticonvulsant
  • antidepressant
  • antipsychotic agent
  • anxiolytic drug
  • central nervous system depressant
  • central nervous system drug
  • pharmaceutical
  • psychotropic drug
  • tranquilizing drug

Functional uses

  • Pharmaceutical

Pharmacology

Lorazepam is a Benzodiazepine.

Regulatory status

Inventories, regulations and trade controls that list this substance

Psychotropic substance

Lorazepam is prohibited on CompoundList. Listings, quotes and messages are disabled. This page is kept for information only.

Listing and enquiries are not allowed for this substance.

Reference: UN Convention on Psychotropic Substances 1971, HS 2022 subheading 2933.91 (benzodiazepines and related substances)

Our policy on controlled substances

Controls

  • US DEA controlled substance or listed chemical
  • Controlled psychotropic substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Lorazepam is traded under.

HS 2933.91Exact HS code

Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…

World exports in 2024
$118M
−26.3% vs 2023, imports $94.2M
2019 to 2024
Top exporters
  1. Italy37.7%
  2. United States22.7%
  3. India * partner reported9.8%
Top importers
  1. Germany13.8%
  2. Spain10.4%
  3. United States10.2%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Lorazepam is indicative (it was matched by name in the HS nomenclature). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Lorazepam, based on the data on this page

What is Lorazepam?

Lorazepam is a benzodiazepine.

What is the CAS number of Lorazepam?

The CAS registry number of Lorazepam is 846-49-1.

What is the molecular formula and weight of Lorazepam?

The molecular formula of Lorazepam is C15H10Cl2N2O2 and its molar mass is 321.16 g/mol.

What is Lorazepam used for?

Use classes: Pharmaceuticals.

Is Lorazepam hazardous?

Lorazepam carries the GHS signal word "Warning". Main hazards: suspected of damaging fertility or the unborn child. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Lorazepam?

Lorazepam is usually classified under HS code 293391 (Alprazolam (INN), camazepam (INN), chlordiazepoxide (INN), clonazepam (INN)…). This is indicative, confirm it with your customs broker before shipping.

Can I buy Lorazepam on CompoundList?

No. Lorazepam is on our prohibited list, so listings, quotes and messages for it are disabled. This page is kept for information only.

Guides for buyers

Practical guides that help when you source, ship or handle Lorazepam

Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page

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