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Methoprene chemical structure, C19H34O3, CAS 40596-69-8
2D chemical structure

Key facts

What buyers check first

Appearance
Clear amber liquid
Boiling point
256 °C
Density
0.9261 g/mL at 20 °C
Flash point
187 °C
Solubility
In water, 1.4 mg/L at room temperature
HS code
291899
Category
Aliphatic and alicyclic building blocks
Illustrative photo, 200 litre blue HDPE drums of liquid in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Methoprene?

Plain description, key identifiers and synonyms

Methoprene is an isopropyl ester and an isopropyl 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate. It has a role as a juvenile hormone mimic.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
propan-2-yl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate
CAS number
40596-69-8 CAS number cross-checkedOther or deprecated CAS: 36557-27-4, 41205-06-5, 52020-07-2
EC number
254-993-2
Molecular formula
C19H34O3
UNII
8B830OJ2UX
MDL number
MFCD00072475
InChIKey
NFGXHKASABOEEW-LDRANXPESA-N
InChI
InChI=1S/C19H34O3/c1-15(2)22-18(20)14-17(4)11-8-10-16(3)12-9-13-19(5,6)21-7/h8,11,14-16H,9-10,12-13H2,1-7H3/b11-8+,17-14+
Canonical SMILES
COC(C)(C)CCCC(C)CC=CC(C)=CC(=O)OC(C)C
Isomeric SMILES
CC(C)OC(=O)/C=C(\C)/C=C/CC(C)CCCC(C)(C)OC

Synonyms

  • Kabat
  • Manta
  • Dianex
  • Juvemon
  • Apex
  • Pharoid
  • Diacon
  • Minex
  • Precor
  • Methoprene S
  • Starbar Inhibitor
  • Altosid IGR
  • Apex (pesticide)
  • Yuvemon
  • Altosid SR 10
  • ZR 515
  • Altosid Liquid Larvicide
  • Methoprenum
  • Metopreno
  • ZPA 1019
  • Bioprene BM Fire Ant Killer Bait
  • OMS 1697
  • ENT 70460
  • Manina
  • Metoprag 20ce
Show all 37 synonyms
  • (E,E)-1-Methylethyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • 2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, 1-methylethyl ester, (2E,4E)-
  • (E,E)-Isopropyl 11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • 2,4-Dodecadienoic acid, 11-methoxy-3,7,11-trimethyl-, 1-methylethyl ester, (E,E)-
  • dl-Isopropyl 11-methoxy-3,7,11-trimethyl-trans-2,4-dodecadienoate
  • Isopropyl(2E,4E)-11-methoxy-3,7,11-trimethyl-2,4-dodecadienoate
  • Altosid PS10
  • Altosid PS 10
  • Altosid
  • propan-2-yl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate
  • Isopropyl 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate
  • Isopropyl (2E,4E)-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Appearance
Clear amber liquidexp.
Odour
Faint fruity odorexp.
Boiling point
256 °Cexp.
Density
0.9261 g/mL at 20 °Cexp.
Flash point
187 °Cexp.
Solubility
In water, 1.4 mg/L at room temperatureexp.
Vapour pressure
2.36 × 10⁻⁴ mm Hg at 25 °Cexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
310.48 g/molcalc.
Exact mass
310.2508 Dacalc.
LogP (octanol/water)
5.06calc.
Topological polar surface area
35.53 Ųcalc.
Hydrogen bond donors
0calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
10calc.
Heavy atoms
22calc.
Rings
0calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.74calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (1 violation)calc.

Calculated for screening. Confirm critical figures with the supplier.

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant
GHS09: Hazardous to the environment
Hazardous to the environment

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
  • H411Toxic to aquatic life with long lasting effects.
Precautionary statements (18)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P273Avoid release to the environment.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P391Collect spillage.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Methoprene suppliers

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All 22 suppliers
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Where suppliers are based

22 suppliers in 7 countries

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Methoprene price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Control of many insect pests (especially Diptera and Pharaoh's ants, but also Coleoptera, Homoptera and Siphonaptera) in public health, stored commodities (including tobacco), food handling, processing and storage establishments, mushroom houses, on animals, and on plants (including glasshouse plants).

Particular uses include control of mosquito larvae, sciarid flies in mushroom houses, cigarette beetles and tobacco moths in stored tobacco, Pharaoh ants, leaf miners on glasshouse chrysanthemums, stored product pests in food and tobacco processing plants and warehouses.

An insecticidal preparation said to act in the manner of a juvenile hormone, which arrests development of insects in the larval stage.

Use classes: Insecticides.

Roles

  • growth regulator
  • insect growth regulator
  • insecticide
  • juvenile hormone mimic
  • pesticide

Functional uses

  • Biocide

How it is made

To a mixture of 10 g of 7-methoxy-3,7-dimethyloctan-1-al, 17 g of diethyl 3-ethoxycarbonyl-2-methylprop-2-enyl phosphonate (77% trans), and 150 ml of dimethylformamide, under nitrogen, 0 °C, with stirring, is added sodium isopropanolate (prepared from 1.5 g of sodium in 150 ml of isopropanol). After addition is complete, the reaction is stirred for 18 hours at room temperature and then worked up by extraction with hexane to yield isopropyl-11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate (mostly trans-2, trans-4), which can be chromatographed and distilled for further purification.

Isopropanol + bromoacetic acid + chloroacetone + methoxycitronellal (esterification/Reformatsky reaction/dehydration/Wittig reaction

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Methoprene is traded under.

HS 2918.99Indicative HS code

Carboxylic acids, with additional oxygen function (not alcohol, phenol, aldehyde or ketone)…

World exports in 2024
$1.46B
−1.1% vs 2023, imports $1.54B
2019 to 2024
Top exporters
  1. China40.0%
  2. India * partner reported26.6%
  3. Germany8.0%
Top importers
  1. United States25.6%
  2. Brazil6.7%
  3. Argentina5.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Methoprene is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Methoprene, based on the data on this page

What is Methoprene?

Methoprene is an isopropyl ester and an isopropyl 11-methoxy-3,7,11-trimethyldodeca-2,4-dienoate. It has a role as a juvenile hormone mimic.

What is the CAS number of Methoprene?

The CAS registry number of Methoprene is 40596-69-8. Other or deprecated CAS numbers: 36557-27-4, 41205-06-5, 52020-07-2.

What is the molecular formula and weight of Methoprene?

The molecular formula of Methoprene is C19H34O3 and its molar mass is 310.48 g/mol.

What is Methoprene used for?

Control of many insect pests (especially Diptera and Pharaoh's ants, but also Coleoptera, Homoptera and Siphonaptera) in public health, stored commodities (including tobacco), food handling, processing and storage establishments, mushroom houses, on animals, and on plants (including glasshouse plants).

Is Methoprene hazardous?

Methoprene carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Methoprene?

Methoprene is usually classified under HS code 291899 (Carboxylic acids with additional oxygen function and their anhydrides, halides…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Methoprene?

CompoundList lists 22 suppliers of Methoprene in China, United States, Canada, France and 3 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Methoprene?

Suppliers quote Methoprene on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Methoprene

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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