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Aliphatic and alicyclic building blocks

Mitindomide

Also known as Mitindomida, Mitindomidum, 3a,3b,4,4a,7a,8a,8b-octahydro-4,8-ethenopyrrolo(3',4':3,4)cyclobut(1,2-f)isoindole-1,3,5,7(2H,6H)-tetrone

CAS 10403-51-7Formula C14H12N2O4Molar mass 272.26 g/mol
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Mitindomide chemical structure, C14H12N2O4, CAS 10403-51-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
10403-51-7
Formula
C14H12N2O4
Molar mass
272.26 g/mol
Solubility
P- dioxane slightly soluble (mg/mL)
HS code
292519
Category
Aliphatic and alicyclic building blocks

What is Mitindomide?

Plain description, key identifiers and synonyms

Mitindomide is a bisdioxopiperazines analog with antineoplastic activity. Mitinomide inhibits topoisomerase II and slowly promotes DNA-interstrand cross-linking, thereby inhibiting DNA repair, RNA and protein synthesis. This agent acts without increasing topoisomerase II-DNA covalent cleavable complex formation, as do most topoisomerase inhibitors. (NCI04)

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(1S,2R,3S,7R,8S,9R,10R,14S)-5,12-diazapentacyclo[7.5.2.02,8.03,7.010,14]hexadec-15-ene-4,6,11,13-tetrone
CAS number
10403-51-7 CAS number cross-checked
Molecular formula
C14H12N2O4
UNII
DK61ZER6T7
InChIKey
DRCJGCOYHLTVNR-ZUIZSQJWSA-N
InChI
InChI=1S/C14H12N2O4/c17-11-7-3-1-2-4(8(7)12(18)15-11)6-5(3)9-10(6)14(20)16-13(9)19/h1-10H,(H,15,17,18)(H,16,19,20)/t3-,4+,5+,6-,7-,8+,9-,10+
Canonical SMILES
O=C1NC(=O)C2C3C=CC(C12)C1C2C(=O)NC(=O)C2C31
Isomeric SMILES
C1=C[C@H]2[C@@H]3[C@H]([C@@H]1[C@@H]4[C@H]2C(=O)NC4=O)[C@@H]5[C@H]3C(=O)NC5=O

Synonyms

  • Mitindomida
  • Mitindomidum
  • 3a,3b,4,4a,7a,8a,8b-octahydro-4,8-ethenopyrrolo(3',4':3,4)cyclobut(1,2-f)isoindole-1,3,5,7(2H,6H)-tetrone
  • tricyclo(4.2.2.0(2,5))dec-9-ene-3,4,7,8-tetracarboxylic acid diimide
  • 4, 8-Ethenopyrrolo(3',4':3,4)cyclobut(1,2-f)isoindole-1,3,5,7(2H, 6H)tetrone, octahydro-
  • (1R*,2S*,3R*,4S*,5R*,6S*,7S*,8R*)-Tricyclo(4.2.2.0(sup 2,5))dec-9-ene-3,4,7,8-tetracarboxylic 3,4:7,8-diimide
  • Tricyclodecenetetracarboxydiimide
  • mitin-domide
  • Tricyclo(4.2.2.0(sup 2,5))-dec-9-ene-3,4,7,8-tetracarboxylic(3,4,:7,8)diimide
  • 1alpha,6alpha-Tricyclo(4.2.2.0(2,5))dec-9-en-3,4,7,8-bis(dicarboximid)
  • Tricyclo(4.2.2.0(2,5))dec-9-en-3,4,7,8-tetracarboxulic 3,4,7,8-diimide
  • 4,8-Ethenopyrrolo(3',4':3,4)cyclobut(1,2-f)isoindole-1,3,5,7(2H,6H)tetrone, octahydro-
  • 4,8-Ethenopyrrolo(3',4':3,4)cyclobut(1,2-f)isoindole-1,3,5,7(2H,6H)-tetrone, 3a,3b,4,4a,7a,8,8a,8b-octahydro-
  • (1S,2R,3S,7R,8S,9R,10R,14S)-5,12-diazapentacyclo[7.5.2.02,8.03,7.010,14]hexadec-15-ene-4,6,11,13-tetrone
  • (3aR,3bS,4R,4aR,7aS,8S,8aR,8bS)-Octahydro-4,8-ethenopyrrolo[3',4':3,4]cyclobuta[1,2-f]isoindole-1,3,5,7(2H,6H)-tetrone

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Solubility
P- dioxane slightly soluble (mg/mL)exp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
272.26 g/molcalc.
Exact mass
272.0797 Dacalc.
LogP (octanol/water)
-1.17calc.
Topological polar surface area
92.34 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
20calc.
Rings
6calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.57calc.
Formal charge
0calc.
Stereocentres
8calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1NC(=O)C2C3C=CC(C12)C1C2C(=O)NC(=O)C2C31

O=C1NC(=O)C2C3C=CC(C12)C1C2C(=O)NC(=O)C2C31

6 rings, 20 atoms.

8 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

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Mitindomide price

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Uses and applications

What the substance is used for, by industry and function

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Mitindomide is traded under.

HS 2925.19Indicative HS code

Imides and their derivatives, salts thereof, other

World exports in 2024
$295M
+11.7% vs 2023, imports $348M
2019 to 2024
Top exporters
  1. China29.7%
  2. Japan22.7%
  3. United Kingdom10.0%
Top importers
  1. United States12.7%
  2. Brazil12.6%
  3. China10.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Mitindomide is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Mitindomide, based on the data on this page

What is Mitindomide?

Mitindomide is a bisdioxopiperazines analog with antineoplastic activity. Mitinomide inhibits topoisomerase II and slowly promotes DNA-interstrand cross-linking, thereby inhibiting DNA repair, RNA and protein synthesis.

What is the CAS number of Mitindomide?

The CAS registry number of Mitindomide is 10403-51-7.

What is the molecular formula and weight of Mitindomide?

The molecular formula of Mitindomide is C14H12N2O4 and its molar mass is 272.26 g/mol.

What is Mitindomide used for?

Known uses and roles of Mitindomide include building blocks in research and laboratory and screening compounds in research and laboratory.

Is Mitindomide hazardous?

No GHS hazard classification for Mitindomide is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Mitindomide?

Mitindomide is usually classified under HS code 292519 (Imides and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Mitindomide?

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What is the price of Mitindomide?

Suppliers quote Mitindomide on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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