CompoundList

Naphthazarin

Also known as 5,8-Dihydroxy-1,4-naphthoquinone, 5,8-dihydroxynaphthalene-1,4-dione, Naphthazarine

Naphthazarin chemical structure, C10H6O4, CAS 475-38-7
2D chemical structure

Key facts

What buyers check first

CAS number
475-38-7
Formula
C10H6O4
Molar mass
190.15 g/mol
EC number
207-495-4
HS code
291469
Category
Insecticides and acaricides

What is Naphthazarin?

Plain description, key identifiers and synonyms

Naphthazarin is a naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups. It has a role as a geroprotector, an acaricide, an antibacterial agent, an antineoplastic agent, an apoptosis inducer and a plant metabolite.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
5,8-dihydroxynaphthalene-1,4-dione
CAS number
475-38-7 CAS number cross-checked
EC number
207-495-4
Molecular formula
C10H6O4
UNII
S9IX5I5C0K
MDL number
MFCD00001685
INCI name
NAPHTHAZARIN
InChIKey
RQNVIKXOOKXAJQ-UHFFFAOYSA-N
InChI
InChI=1S/C10H6O4/c11-5-1-2-6(12)10-8(14)4-3-7(13)9(5)10/h1-4,11-12H
SMILES (canonical and isomeric)
C1=CC(=C2C(=O)C=CC(=O)C2=C1O)O

Synonyms

  • 5,8-Dihydroxy-1,4-naphthoquinone
  • 5,8-dihydroxynaphthalene-1,4-dione
  • Naphthazarine
  • Naphthazarone
  • 5,8-Dihydroxynaphthoquinone
  • 5,8-Dihydroxy-1,4-naphthalenedione
  • 5,8-Dihydroxy-1,4-naphthosemiquinone
  • 1,4-Naphthoquinone, 5,8-dihydroxy-
  • 1,4-Naphthalenedione, 5,8-dihydroxy-
  • 5,8-dioxy-1,4-naphthoquinone
  • Naphthazalin
  • 5,8-Dihydroxy-[1,4]naphthoquinone
  • doi:10.14272/RQNVIKXOOKXAJQ-UHFFFAOYSA-N.1
  • Dihydroxynaphthoquinone
  • Napthazarin nphz
  • 5,4-naphthosemiquinone
  • 1, 5,8-dihydroxy-
  • 5,8-Dihydroxynaphthaquinone
  • 5,8-dihydroxy-1,4-dihydronaphthalene-1,4-dione
  • Dihydroxynaphthalene-1,4-dione
  • 1,5-dihydroxy-4,8-naphthoquinone
  • Dihydroxy-1,4-naphthoquinone,5,8-
  • 10.14272/Rqnvikxookxajq-uhfffaoysa-n
  • Dihydroxy-1,4-naphthalenedione, 5,8-
  • 10.14272/Rqnvikxookxajq-uhfffaoysa-n.1
Show all 27 synonyms
  • doi:10.14272/RQNVIKXOOKXAJQ-UHFFFAOYSA-N
  • 5,8-Dihydroxy-1,4-naphthoquinone, technical grade

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
190.15 g/molcalc.
Exact mass
190.0266 Dacalc.
LogP (octanol/water)
1.03calc.
Topological polar surface area
74.6 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
0calc.
Heavy atoms
14calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1C=CC(=O)c2ccccc21

O=C1C=CC(=O)c2ccccc21

2 rings, 12 atoms, the 1,4-Naphthoquinone ring system.

875 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H312Harmful in contact with skin.
  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H332Harmful if inhaled.
  • H335May cause respiratory irritation.
Precautionary statements (20)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P317Get medical help.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P330Rinse mouth.
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Naphthazarin suppliers

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All 7 suppliers
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Where suppliers are based

7 suppliers in 3 countries

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Naphthazarin price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Cosmetic ingredient, INCI name NAPHTHAZARIN(colorant, hair conditioning)

Pharmacological actions

  • Antineoplastic Agents

Roles

  • acaricide
  • antibacterial agent
  • antimicrobial agent
  • antineoplastic agent
  • apoptosis inducer
  • eukaryotic metabolite
  • geroprotector
  • metabolite
  • pesticide
  • pharmaceutical
  • plant metabolite
  • protective agent

Cosmetic functions

  • Colorant
  • Hair conditioning

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Naphthazarin is traded under.

HS 2914.69Indicative HS code

Quinones, other

World exports in 2024
$162M
−10.1% vs 2023, imports $157M
2019 to 2024
Top exporters
  1. China32.8%
  2. Netherlands29.3%
  3. Japan13.8%
Top importers
  1. United States23.0%
  2. India * partner reported16.1%
  3. Thailand7.9%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Naphthazarin is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Naphthazarin, based on the data on this page

What is Naphthazarin?

Naphthazarin is a naphthoquinone that is 1,4-naphthoquinone in which the hydrogens at positions 5 and 8 are replaced by hydroxy groups. It has a role as a geroprotector, an acaricide, an antibacterial agent, an antineoplastic agent, an apoptosis inducer and a plant metabolite.

What is the CAS number of Naphthazarin?

The CAS registry number of Naphthazarin is 475-38-7.

What is the molecular formula and weight of Naphthazarin?

The molecular formula of Naphthazarin is C10H6O4 and its molar mass is 190.15 g/mol.

What is Naphthazarin used for?

Known uses and roles of Naphthazarin include hair conditioning agents in cosmetics and personal care, colorants in cosmetics and personal care, acaricides and miticides in agriculture and crop protection, acaricide, antibacterial agent and 13 more.

Is Naphthazarin hazardous?

Naphthazarin carries the GHS signal word "Warning". Main hazards: harmful if swallowed, harmful in contact with skin, causes skin irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Naphthazarin?

Naphthazarin is usually classified under HS code 291469 (Quinones, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Naphthazarin?

CompoundList lists 7 suppliers of Naphthazarin in China, United States and Netherlands. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Naphthazarin?

Suppliers quote Naphthazarin on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Naphthazarin

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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