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Murcko scaffold

1,4-Naphthoquinone scaffold

876 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
12
Chemicals
876
With full pages
141
Scaffold SMILES

O=C1C=CC(=O)c2ccccc21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the 1,4-Naphthoquinone page
Murcko scaffold O=C1C=CC(=O)c2ccccc21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 876 chemicals

2-(2-Hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone chemical structure, C13H12O3S, CAS 59147-84-1
2-(2-Hydroxyethylsulfanyl)-3-methyl-1,4-naphthoquinone
CAS 59147-84-1C13H12O3S
2,3-Dimethoxy-1,4-naphthoquinone chemical structure, C12H10O4, CAS 6956-96-3
2,3-Dimethoxy-1,4-naphthoquinone
CAS 6956-96-3C12H10O4
Juglone chemical structure, C10H6O3, CAS 481-39-0
Juglone
CAS 481-39-0C10H6O3
Menadione chemical structure, C11H8O2, CAS 58-27-5
Menadione
CAS 58-27-5C11H8O2
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-1,4-naphthoquinone chemical structure, C31H46O2, CAS 81818-54-4
2-Methyl-3-(3,7,11,15-tetramethyl-2-hexadecen-1-yl)-1,4-naphthoquinone
CAS 81818-54-4C31H46O2
(±)-Shikonin chemical structure, C16H16O5, CAS 54952-43-1
(±)-Shikonin
CAS 54952-43-1C16H16O5
Dichlone chemical structure, C10H4Cl2O2, CAS 117-80-6
Dichlone
CAS 117-80-6C10H4Cl2O2
1,4-Naphthoquinone chemical structure, C10H6O2, CAS 130-15-4
1,4-Naphthoquinone
CAS 130-15-4C10H6O2
Naphthazarin chemical structure, C10H6O4, CAS 475-38-7
Naphthazarin
CAS 475-38-7C10H6O4
Javanicin chemical structure, C15H14O6, CAS 476-45-9
Javanicin
CAS 476-45-9C15H14O6
Plumbagin chemical structure, C11H8O3, CAS 481-42-5
Plumbagin
CAS 481-42-5C11H8O3
2-Chloro-1,4-naphthoquinone chemical structure, C10H5ClO2, CAS 1010-60-2
2-Chloro-1,4-naphthoquinone
CAS 1010-60-2C10H5ClO2
2,3-Dimethyl-1,4-naphthoquinone chemical structure, C12H10O2, CAS 2197-57-1
2,3-Dimethyl-1,4-naphthoquinone
CAS 2197-57-1C12H10O2
2-Dimethylamino-1,4-naphthoquinone chemical structure, C12H11NO2, CAS 2348-79-0
2-Dimethylamino-1,4-naphthoquinone
CAS 2348-79-0C12H11NO2
2-Methoxy-1,4-naphthoquinone chemical structure, C11H8O3, CAS 2348-82-5
2-Methoxy-1,4-naphthoquinone
CAS 2348-82-5C11H8O3
Quinoclamine chemical structure, C10H6ClNO2, CAS 2797-51-5
Quinoclamine
CAS 2797-51-5C10H6ClNO2
5,8-Dihydroxy-2,7-dimethoxy-1,4-naphthoquinone chemical structure, C12H10O6, CAS 2808-46-0
5,8-Dihydroxy-2,7-dimethoxy-1,4-naphthoquinone
CAS 2808-46-0C12H10O6
2-Chloro-3-(dimethylamino)-1,4-naphthalenedione chemical structure, C12H10ClNO2, CAS 5350-26-5
2-Chloro-3-(dimethylamino)-1,4-naphthalenedione
CAS 5350-26-5C12H10ClNO2
1,4-Naphthoquinone, 2-diethylamino- chemical structure, C14H15NO2, CAS 14422-78-7
1,4-Naphthoquinone, 2-diethylamino-
CAS 14422-78-7C14H15NO2
Ramentaceone chemical structure, C11H8O3, CAS 14787-38-3
Ramentaceone
CAS 14787-38-3C11H8O3
2-Chloro-3-methoxy-1,4-naphthalenedione chemical structure, C11H7ClO3, CAS 15707-32-1
2-Chloro-3-methoxy-1,4-naphthalenedione
CAS 15707-32-1C11H7ClO3
2-Chloro-3-((3-(dimethylamino)propyl)amino)-1,4-naphthalenedione chemical structure, C15H17ClN2O2, CAS 22272-09-9
2-Chloro-3-((3-(dimethylamino)propyl)amino)-1,4-naphthalenedione
CAS 22272-09-9C15H17ClN2O2
1,4-Naphthoquinone, 2-(sec-butylamino)-3-chloro- chemical structure, C14H14ClNO2, CAS 22272-32-8
1,4-Naphthoquinone, 2-(sec-butylamino)-3-chloro-
CAS 22272-32-8C14H14ClNO2
2-((1,1-Dimethylethyl)amino)-1,4-naphthalenedione chemical structure, C14H15NO2, CAS 23434-49-3
2-((1,1-Dimethylethyl)amino)-1,4-naphthalenedione
CAS 23434-49-3C14H15NO2