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Analgesics and anti-inflammatories

Nedocromil

Also known as Nedocromilo, Nedocromilum, FPL 59002

CAS 69049-73-6Formula C19H17NO7Molar mass 371.35 g/molEC 806-161-0
GHS signal word: Warning. Pictograms: Harmful or irritant 70 suppliers listed Drug substance
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Nedocromil chemical structure, C19H17NO7, CAS 69049-73-6
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
69049-73-6
Formula
C19H17NO7
Molar mass
371.35 g/mol
EC number
806-161-0
HS code
293499
Category
Analgesics and anti-inflammatories

What is Nedocromil?

Plain description, key identifiers and synonyms

Nedocromil is an organic heterotricyclic compound and a dicarboxylic acid. It has a role as a non-steroidal anti-inflammatory drug, an anti-asthmatic drug and an anti-allergic agent. It is a conjugate acid of a nedocromil(2-).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
9-ethyl-4,6-dioxo-10-propylpyrano[3,2-g]quinoline-2,8-dicarboxylic acid
CAS number
69049-73-6 CAS number cross-checked
EC number
806-161-0
Molecular formula
C19H17NO7
UNII
0B535E0BN0
MDL number
MFCD00864606
InChIKey
RQTOOFIXOKYGAN-UHFFFAOYSA-N
InChI
InChI=1S/C19H17NO7/c1-3-5-9-16-10(13(21)7-12(18(23)24)20(16)4-2)6-11-14(22)8-15(19(25)26)27-17(9)11/h6-8H,3-5H2,1-2H3,(H,23,24)(H,25,26)
SMILES (canonical and isomeric)
CCCC1=C2C(=CC3=C1OC(=CC3=O)C(=O)O)C(=O)C=C(N2CC)C(=O)O

Synonyms

  • Nedocromilo
  • Nedocromilum
  • FPL 59002
  • 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)quinoline-2,8-dicarboxylic acid
  • 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano(3,2-g)chinolin-2,8-dicarbonsaeure
  • 9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid
  • Tilavist
  • 4H-Pyrano(3,2-g)quinoline-2,8-dicarboxylic acid, 9-ethyl-6,9-dihydro-4,6-dioxo-10-propyl-
  • 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno[7,6-b]pyridine-2,8-dicarboxylic acid
  • Nedocromil, Disodium Salt
  • Tilaire
  • Irtan
  • Tilad
  • 9-ethyl-4,6-dioxo-10-propylpyrano(5,6-g)quinoline-2,8-dicarboxylic acid
  • 9-ethyl-4,6-dioxo-10-propylpyrano[5,6-g]quinoline-2,8-dicarboxylic acid
  • nedocromil calicum
  • 9-ethyl-4,6-dioxo-10-propyl-4H,6H,9H-chromeno(7,6-b)pyridine-2,8-dicarboxylic acid
  • Nedocromil, Calcium Salt (1:1)
  • Sodium, Nedocromil
  • Calcium, Nedocromil
  • 9-ethyl-4,6-dioxo-10-propyl-6,9-dihydro-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid
  • 9-ethyl-4,6-dioxo-10-propylpyrano[3,2-g]quinoline-2,8-dicarboxylic acid
  • Nedocromil (Standard)
  • Nedocromil (USAN/INN)
  • Nedocromil, >=98% (HPLC)
Show all 26 synonyms
  • 9-ethyl-4,6-dioxo-10-propyl-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
371.35 g/molcalc.
Exact mass
371.1005 Dacalc.
LogP (octanol/water)
2.48calc.
Topological polar surface area
126.8 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
5calc.
Rotatable bonds
5calc.
Heavy atoms
27calc.
Rings
3calc.
Aromatic rings
3calc.
Fraction sp3 carbons
0.26calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=c1cc[nH]c2cc3occc(=O)c3cc12

O=c1cc[nH]c2cc3occc(=O)c3cc12

3 rings, 16 atoms.

5 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H319Causes serious eye irritation.
Precautionary statements (4)
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P337 + P317If eye irritation persists: Get medical help.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Nedocromil suppliers

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Where suppliers are based

70 suppliers in 12 countries

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Nedocromil price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Use classes: Pharmaceuticals.

Pharmacological actions

  • Anti-Allergic Agents
  • Anti-Asthmatic Agents
  • Anti-Inflammatory Agents
  • Mast Cell Stabilizers

Roles

  • anti-allergic agent
  • anti-asthmatic agent
  • anti-asthmatic drug
  • anti-inflammatory agent
  • anti-inflammatory drug
  • antirheumatic drug
  • nasal decongestant
  • non-steroidal anti-inflammatory drug
  • pharmaceutical

Pharmacology

Nedocromil is a Mast Cell Stabilizer. The physiologic effect of nedocromil is by means of Decreased Histamine Release.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Nedocromil is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Nedocromil is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Nedocromil, based on the data on this page

What is Nedocromil?

Nedocromil is an organic heterotricyclic compound and a dicarboxylic acid. It has a role as a non-steroidal anti-inflammatory drug, an anti-asthmatic drug and an anti-allergic agent. It is a conjugate acid of a nedocromil(2-).

Is Nedocromil hazardous?

Nedocromil carries the GHS signal word "Warning". Main hazards: causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

Guides for buyers

Practical guides that help when you source, ship or handle Nedocromil

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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