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Hormones and steroids

Ogen

Also known as Estropipate, Piperazine estrone sulfate, Sulestrex

CAS 7280-37-7Formula C22H32N2O5SMolar mass 436.57 g/molEC 230-696-3
GHS signal word: Danger. Pictograms: Harmful or irritant, Serious health hazard 8 suppliers listed Drug substance
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Ogen chemical structure, C22H32N2O5S, CAS 7280-37-7
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
7280-37-7
Formula
C22H32N2O5S
Molar mass
436.57 g/mol
EC number
230-696-3
HS code
293723
Category
Hormones and steroids

What is Ogen?

Plain description, key identifiers and synonyms

Estropipate is a steroid sulfate and a piperazinium salt. It is functionally related to an estrone.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate, piperazine
CAS number
7280-37-7 CAS number cross-checked
EC number
230-696-3
Molecular formula
C22H32N2O5S
UNII
SVI38UY019
MDL number
MFCD00867399
InChIKey
HZEQBCVBILBTEP-ZFINNJDLSA-N
InChI
InChI=1S/C18H22O5S.C4H10N2/c1-18-9-8-14-13-5-3-12(23-24(20,21)22)10-11(13)2-4-15(14)16(18)6-7-17(18)19;1-2-6-4-3-5-1/h3,5,10,14-16H,2,4,6-9H2,1H3,(H,20,21,22);5-6H,1-4H2/t14-,15-,16+,18+;/m1./s1
Canonical SMILES
C1CNCCN1.CC12CCC3c4ccc(OS(=O)(=O)O)cc4CCC3C1CCC2=O
Isomeric SMILES
C[C@]12CC[C@H]3[C@H]([C@@H]1CCC2=O)CCC4=C3C=CC(=C4)OS(=O)(=O)O.C1CNCCN1

Synonyms

  • Estropipate
  • Piperazine estrone sulfate
  • Sulestrex
  • Sulestrex piperazine
  • Estrone sulfate piperazine salt
  • piperazine estrone sulphate
  • OGEN 5
  • OGEN 2.5
  • OGEN .625
  • OGEN 1.25
  • Estrone Hydrogen Sulfate compound with Piperazine(1:1)
  • Piperazine, compound with 3-(Sulfooxy)estra-1,3,5(10)-trien-17-one(1:1)
  • Ortho-Est, Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with Piperazine(1:1)
  • Harmogen
  • Ortho-Est
  • Piperazine estronesulfate
  • Estrone hydrogen sulfate compound with piperazine (1:1)
  • [(8R,9S,13S,14S)-13-methyl-17-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-yl] hydrogen sulfate, piperazine
  • Piperazine oestrone sulphate
  • Estropipate (USP)
  • Ogen (TN)
  • Piperazineestronesulfate
  • Estropipate (Standard)
  • Conjugated estrogens: piperazine estrone sulfate
  • Estra-1,3,5(10)-trien-17-one 3-sulphate, compound with piperazine (1:1)
Show all 30 synonyms
  • Estropipate, >=98% (HPLC), powder
  • Estrone hydrogen sulphate compound with piperazine (1:1)
  • Estropipate, United States Pharmacopeia (USP) Reference Standard
  • 17-oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate - piperazine (1:1)
  • 17-Oxoestra-1,3,5(10)-trien-3-yl hydrogen sulfate--piperazine (1/1)

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
436.57 g/molcalc.
Exact mass
436.2032 Dacalc.
LogP (octanol/water)
2.47calc.
Topological polar surface area
104.7 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
2calc.
Heavy atoms
30calc.
Rings
5calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.68calc.
Formal charge
0calc.
Stereocentres
4calc.
Components
2calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, O=C1CCC2C1CCC1c3ccccc3CCC12

O=C1CCC2C1CCC1c3ccccc3CCC12

4 rings, 18 atoms.

176 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Danger
GHS07: Harmful or irritant
Harmful or irritant
GHS08: Serious health hazard
Serious health hazard

Hazard statements

  • H302Harmful if swallowed.
  • H350May cause cancer.
  • H351Suspected of causing cancer.
  • H360May damage fertility or the unborn child.
  • H362May cause harm to breast-fed children.
Precautionary statements (11)
  • P203Obtain, read and follow all safety instructions before use.
  • P260Do not breathe dust, fume, gas, mist, vapours or spray.
  • P263Avoid contact during pregnancy and while nursing.
  • P264Wash skin thoroughly after handling.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P318If exposed or concerned, get medical advice.
  • P330Rinse mouth.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Ogen suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 8 suppliers
8 of 8 offers
  • Sterling S.p.A.
    Italy, Corciano ManufacturerUnclaimed profile
    EstropipateGrade, purity and minimum order on request
    Price on request
    View
  • Aceschem Inc
    United States, FriscoUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View
  • AChemBlock
    United States, HaywardUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View
  • Apexmol
    China, ChongqingUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View
  • Avantor Inc.
    United States, Radnor ManufacturerUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View
  • BioChemPartner
    China, ShangHaiUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View
  • BioCrick
    China, ChengduUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View
  • ChemShuttle
    United States, BurlingameUnclaimed profile
    OgenGrade, purity and minimum order on request
    Price on request
    View

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

8 suppliers in 3 countries

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Ogen price

Indicative price range per kg from live supplier offers

No published prices right now

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Contraceptive Agents, Hormonal

Roles

  • bone density conservation agent
  • pharmaceutical

Pharmacology

Estropipate is a natural estrogenic substance composed of estrone sulfate and piperazine. Estropipate diffuses through the cell membrane and binds to and subsequently activates the nuclear estrogen receptor found in the reproductive tract, breast, pituitary, hypothalamus, liver, and bone. The activated complex binds to the estrogen response element on the DNA and activates the transcription of genes involved in the functioning of the female reproductive system and secondary sex characteristics.

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • Active ingredient in FDA approved drug labels

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Ogen is traded under.

HS 2937.23Indicative HS code

Oestrogens and progestogens

World exports in 2024
$762M
−2.3% vs 2023, imports $693M
2019 to 2024
Top exporters
  1. China42.9%
  2. Italy18.4%
  3. Netherlands8.9%
Top importers
  1. India * partner reported12.1%
  2. United States11.0%
  3. Belgium8.3%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Ogen is indicative (it is known at chapter level only). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Ogen, based on the data on this page

What is Ogen?

Estropipate is a steroid sulfate and a piperazinium salt. It is functionally related to an estrone.

What is the CAS number of Ogen?

The CAS registry number of Ogen is 7280-37-7.

What is the molecular formula and weight of Ogen?

The molecular formula of Ogen is C22H32N2O5S and its molar mass is 436.57 g/mol.

What is Ogen used for?

Known uses and roles of Ogen include hormones and steroids in pharmaceuticals, bone density conservation agent, pharmaceutical and contraceptive agents, hormonal.

Is Ogen hazardous?

Ogen carries the GHS signal word "Danger". Main hazards: harmful if swallowed, may cause cancer, suspected of causing cancer. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Ogen?

Ogen is usually classified under HS code 293723 (Oestrogens and progestogens). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Ogen?

CompoundList lists 8 suppliers of Ogen in United States, China and Italy. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Ogen?

Suppliers quote Ogen on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Ogen

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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