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Antibiotics and anti-infectives

Propamidine

Also known as Propamidina, Propamidinum, 4,4'-(Trimethylenedioxy)dibenzamidine

CAS 104-32-5Formula C17H20N4O2Molar mass 312.37 g/molEC 203-195-2
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Propamidine chemical structure, C17H20N4O2, CAS 104-32-5
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
104-32-5
Formula
C17H20N4O2
Molar mass
312.37 g/mol
EC number
203-195-2
HS code
292529
Category
Antibiotics and anti-infectives

What is Propamidine?

Plain description, key identifiers and synonyms

Propamidine is a polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. It has a role as an antimicrobial agent and an antiseptic drug. It is a member of guanidines, an aromatic ether and a polyether. It is functionally related to a propane-1,3-diol. It is a conjugate base of a propamidine(2+).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
4-[3-(4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide
CAS number
104-32-5 CAS number cross-checked
EC number
203-195-2
Molecular formula
C17H20N4O2
UNII
G20G12V769
InChIKey
WTFXJFJYEJZMFO-UHFFFAOYSA-N
InChI
InChI=1S/C17H20N4O2/c18-16(19)12-2-6-14(7-3-12)22-10-1-11-23-15-8-4-13(5-9-15)17(20)21/h2-9H,1,10-11H2,(H3,18,19)(H3,20,21)
SMILES (canonical and isomeric)
C1=CC(=CC=C1C(=N)N)OCCCOC2=CC=C(C=C2)C(=N)N

Synonyms

  • Propamidina
  • Propamidinum
  • 4,4'-(Trimethylenedioxy)dibenzamidine
  • M&B 782 FREE BASE
  • M&B-782 FREE BASE
  • 4,4'-(1,3-Propanediylbis(oxy))bis-benzenecarboximidamide
  • DAPP-H
  • 1,3-bis(p-amidinophenoxy)propane
  • 1,3-di-(4-amidinophenoxy)propane
  • 1,3-di-(p-amidinophenoxymethyl)-propane
  • 4-(3-(4-carbamimidoylphenoxy)propoxy)benzene-1-carboximidamide
  • 4-[3-(4-carbamimidoylphenoxy)propoxy]benzenecarboximidamide
  • Benzenecarboximidamide, 4,4'-[1,3-propanediylbis(oxy)]bis-
  • 1,3-Bis(amidinophenoxy)propane
  • Propamide dihydrochloride
  • Propamidine (INN)
  • 4,4'-(propane-1,3-diylbis(oxy))dibenzimidamide
  • 4-[3-(4-carbamimidoylphenoxy)propoxy]benzamidine
  • Panamidin
  • 4,4'-[propane-1,3-diylbis(oxy)]di(benzene-1-carboximidamide)
  • 4,4'-Diamidino-1,3-diphenoxypropane dihydrochloride
  • Propamidine chloride
  • M&B 782
  • p,p'-(Trimethylenedioxy)dibenzamidine-
  • 4,4'-(Trimethylededioxy)dibenzamidine
Show all 30 synonyms
  • 4,4'-[propane-1,3-diylbis(oxy)]dibenzenecarboximidamide
  • 4,4'-[1,3-Propanediylbis(oxy)]bisbenzenecarboximidamide-
  • 4,4'-(1,3-Propanediylbis(oxy)bis(benzenecarboximidamide)
  • 4-(3-(4-(Amino(imino)methyl)phenoxy)propoxy)benzenecarboximidamide
  • Benzenecarboximidamide, {4,4'-[1,3-propanediylbis(oxy)]bis-,} dihydrochloride

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
312.37 g/molcalc.
Exact mass
312.1586 Dacalc.
LogP (octanol/water)
2.1calc.
Topological polar surface area
118.2 Ųcalc.
Hydrogen bond donors
4calc.
Hydrogen bond acceptors
4calc.
Rotatable bonds
8calc.
Heavy atoms
23calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0.18calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(OCCCOc2ccccc2)cc1

c1ccc(OCCCOc2ccccc2)cc1

2 rings, 17 atoms, the 1,3-Diphenoxypropane ring system.

259 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Propamidine suppliers

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Propamidine price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Antiprotozoal Agents

Roles

  • antiinfective agent
  • antimicrobial agent
  • antiseptic drug
  • ophthalmology drug
  • pharmaceutical

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Propamidine is traded under.

HS 2925.29Indicative HS code

Imines and their derivatives, salts thereof, other

World exports in 2024
$1.8B
+12.4% vs 2023, imports $1.84B
2019 to 2024
Top exporters
  1. China35.9%
  2. France * partner reported15.5%
  3. Germany9.1%
Top importers
  1. United States13.3%
  2. China13.0%
  3. Brazil9.7%

* Partner reported figures, a lower bound.

Reported customs values in USD, not prices.Full trade data

The HS code shown for Propamidine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Propamidine, based on the data on this page

What is Propamidine?

Propamidine is a polyether that is the bis(4-guanidinophenyl) ether of propane-1,3-diol. Used (as its isethionate salt) for the treatment of minor eye or eyelid infections, such as conjunctivitis and blepharitis. It has a role as an antimicrobial agent and an antiseptic drug.

What is the CAS number of Propamidine?

The CAS registry number of Propamidine is 104-32-5.

What is the molecular formula and weight of Propamidine?

The molecular formula of Propamidine is C17H20N4O2 and its molar mass is 312.37 g/mol.

What is Propamidine used for?

Known uses and roles of Propamidine include antiinfective agent, antimicrobial agent, antiseptic drug, ophthalmology drug, pharmaceutical and 1 more.

Is Propamidine hazardous?

No GHS hazard classification for Propamidine is recorded on CompoundList yet. That does not prove it is safe. Always read the supplier safety data sheet.

What is the HS code of Propamidine?

Propamidine is usually classified under HS code 292529 (Imines and their derivatives, salts thereof, other). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Propamidine?

Post a free request on CompoundList and suppliers of Propamidine will send you quotes. Your contact details stay private until you accept a quote.

What is the price of Propamidine?

Suppliers quote Propamidine on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Propamidine

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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