Queuine
Also known as base Q, Q Base, 7-(3,4-trans-4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine
Key facts
What buyers check first
- CAS number
- 72496-59-4
- Formula
- C12H15N5O3
- Molar mass
- 277.28 g/mol
- HS code
- 293359
- Category
- Heterocyclic building blocks
What is Queuine?
Plain description, key identifiers and synonyms
Queuine is a pyrrolopyrimidine. It has a role as an Escherichia coli metabolite. It is a conjugate base of a queuine(1+).
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 2-amino-5-[[[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino]methyl]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
- CAS number
- 72496-59-4 CAS number cross-checkedOther or deprecated CAS: 69565-92-0, 85549-16-2
- Molecular formula
- C12H15N5O3
- UNII
- DAK6EYX2BZ
- InChIKey
- WYROLENTHWJFLR-ACLDMZEESA-N
- InChI
- InChI=1S/C12H15N5O3/c13-12-16-10-8(11(20)17-12)5(4-15-10)3-14-6-1-2-7(18)9(6)19/h1-2,4,6-7,9,14,18-19H,3H2,(H4,13,15,16,17,20)/t6-,7-,9+/m0/s1
- Canonical SMILES
- Nc1nc2[nH]cc(CNC3C=CC(O)C3O)c2c(=O)[nH]1
- Isomeric SMILES
- C1=C[C@@H]([C@@H]([C@H]1NCC2=CNC3=C2C(=O)NC(=N3)N)O)O
Synonyms
- base Q
- Q Base
- 7-(3,4-trans-4,5-cis-dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanine
- 2-amino-5-[[[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino]methyl]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
- 4H-pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-((((1S,4S,5R)-4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-
- 2-amino-5-{[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-ylamino]methyl}-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
- 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-, (1S-(1alpha,4beta,5beta))-
- 2-amino-5-((((1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl)amino)methyl)-3,7-dihydropyrrolo(2,3-d)pyrimidin-4-one
- 2-amino-5-(((1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-ylamino)methyl)-3,7-dihydro-4H-pyrrolo(2,3-d)pyrimidin-4-one
- 5-((((1R,4R,5S)-4,5-dihydroxycyclopent-2-en-1-yl)amino)methyl)-2-imino-1H,2H,3H,4H,7H-pyrrolo(2,3-d)pyrimidin-4-one
- Queuine Hydrochloride
- 2-amino-5-((((1s,4s,5r)-4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-4h-pyrrolo(2,3-d)pyrimidin-4-one
- Queuine-API
- 2-amino-5-[[[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino]methyl]-1,7-dihydropyrrolo[2,3-d]pyrimidin-4-one
- 2-Amino-5-((((1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl)amino)methyl)-1H-pyrrolo[2,3-d]pyrimidin-4(7H)-one
- 2-amino-5-({[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino}methyl)-1,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one
- 2-Amino-5-[[[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino]methyl]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one hydrochloride
- 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-5-(((4,5-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-1,7-dihydro-, (1S-(1alpha,4beta,5.beta.))-
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 277.28 g/molcalc.Computed value |
|---|---|
| Exact mass | 277.1175 Dacalc.Computed value |
| LogP (octanol/water) | -1.42calc.Computed value |
| Topological polar surface area | 140.1 Ųcalc.Computed value |
| Hydrogen bond donors | 6calc.Computed value |
| Hydrogen bond acceptors | 6calc.Computed value |
| Rotatable bonds | 3calc.Computed value |
| Heavy atoms | 20calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 2calc.Computed value |
| Fraction sp3 carbons | 0.33calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (1 violation)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
![Murcko scaffold of this chemical, O=c1[nH]cnc2[nH]cc(CNC3C=CCC3)c12](/scaffold/XOGOIURYEASCPZ-UHFFFAOYSA-N/structure.svg)
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Queuine suppliers
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Post one free request and suppliers who make or trade Queuine can send you quotes. Your contact details stay private until you accept a quote.
Queuine price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- Escherichia coli metabolite
- bacterial metabolite
- metabolite
- prokaryotic metabolite
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Queuine is traded under.
Compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring, other
- Ireland43.6%
- Switzerland * partner reported26.3%
- China7.9%
- Slovenia30.3%
- United States30.1%
- Germany15.3%
* Partner reported figures, a lower bound.
The HS code shown for Queuine is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Related chemicals
Parent and salt forms, stereoisomers, similar structures and isomers
Salt and hydrate forms
Records that share this compound as their parent
![2-Amino-5-[[[(1S,4S,5R)-4,5-dihydroxycyclopent-2-en-1-yl]amino]methyl]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one, hydrochloride chemical structure, C12H16ClN5O3, CAS 85549-16-2](/s/IMQUYNGZFBWKEZ-ZTLFIBQGSA-N.svg)
Stereoisomers and isotopic forms
Same connectivity, different stereochemistry or isotopes (same InChIKey skeleton)
![Rel-2-amino-5-((((1R,4R,5S)-4,5-dihydroxycyclopent-2-en-1-yl)amino)methyl)-3,7-dihydro-4H-pyrrolo[2,3-d]pyrimidin-4-one chemical structure, C12H15N5O3, CAS 69565-92-0](/s/WYROLENTHWJFLR-BHNWBGBOSA-N.svg)
![2-Amino-5-[[(4,5-dihydroxycyclopent-2-en-1-yl)amino]methyl]-3,7-dihydropyrrolo[2,3-d]pyrimidin-4-one chemical structure, C12H15N5O3](/s/WYROLENTHWJFLR-UHFFFAOYSA-N.svg)
Same formula isomers
Different compounds that share this molecular formula
![N-Ethyl-2-{[3-(3-pyridinyl)-4,5-dihydro-5-isoxazolyl]carbonyl}-1-hydrazinecarboxamide chemical structure, C12H15N5O3, CAS 478078-47-6](/s/SKLUCZIJCNIVCA-UHFFFAOYSA-N.svg)
![N-Allyl-2-(1-(2-hydroxyethyl)-4-oxo-1H-pyrazolo[3,4-d]pyrimidin-5(4H)-yl)acetamide chemical structure, C12H15N5O3, CAS 900011-78-1](/s/WWVRAXXZVMLYJU-UHFFFAOYSA-N.svg)
Frequently asked questions
Quick answers about Queuine, based on the data on this page
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Guides for buyers
Practical guides that help when you source, ship or handle Queuine
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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