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Impurities and reference standards

(R)-Timolol

Also known as (+)-timolol, d-Timolol, (2R)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol

CAS 26839-76-9Formula C13H24N4O3SMolar mass 316.43 g/molEC 248-033-1
GHS signal word: Warning. Pictograms: Harmful or irritant
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(R)-Timolol chemical structure, C13H24N4O3S, CAS 26839-76-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
26839-76-9
Formula
C13H24N4O3S
Molar mass
316.43 g/mol
EC number
248-033-1
HS code
293499
Category
Impurities and reference standards

What is (R)-Timolol?

Plain description, key identifiers and synonyms

(R)-timolol is the (R)-(+) (less active) enantiomer of timolol. It is an enantiomer of a (S)-timolol (anhydrous).

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
(2R)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
CAS number
26839-76-9
EC number
248-033-1
Molecular formula
C13H24N4O3S
UNII
2BG20ZUO2E
InChIKey
BLJRIMJGRPQVNF-SNVBAGLBSA-N
InChI
InChI=1S/C13H24N4O3S/c1-13(2,3)14-8-10(18)9-20-12-11(15-21-16-12)17-4-6-19-7-5-17/h10,14,18H,4-9H2,1-3H3/t10-/m1/s1
SMILES
CC(C)(C)NC[C@H](COC1=NSN=C1N2CCOCC2)O

Synonyms

  • (+)-timolol
  • d-Timolol
  • (2R)-1-(tert-butylamino)-3-[(4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy]propan-2-ol
  • Timolol, (R)-
  • (2R)-1-(tert-butylamino)-3-((4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
  • Timolol, (+)-
  • (R)-(+)-Timolol
  • (2r)-1-(tert-butylamino)-3-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}propan-2-ol
  • Timolol EP Impurity A
  • (R)-timolol CRS
  • Timolol Maleate Impurity 17
  • DivK1c_000178
  • Timolol anhydrous, (R)-
  • 1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-2-propanol
  • 2-Propanol,1-[(1,1-dimethylethyl)amino]-3-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]-,(2R)-
  • Timolol maleate impurity a
  • Timolol related compound a
  • (R)-1-(tert-Butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
  • 2-Propanol, 1-(tert-butylamino)-3-((4-morpholino-1,2,5-thiadiazol-3-yl)oxy)-
  • (2R)-1-((1,1-Dimethylethyl)amino)-3-((4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol
  • 2-Propanol, 1-((1,1-dimethylethyl)amino)-3-((4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl)oxy)-, (2R)-

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
316.43 g/molcalc.
Exact mass
316.1569 Dacalc.
LogP (octanol/water)
0.5calc.
Topological polar surface area
79.74 Ųcalc.
Hydrogen bond donors
2calc.
Hydrogen bond acceptors
8calc.
Rotatable bonds
6calc.
Heavy atoms
21calc.
Rings
2calc.
Aromatic rings
1calc.
Fraction sp3 carbons
0.85calc.
Formal charge
0calc.
Stereocentres
1calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1nsnc1N1CCOCC1

c1nsnc1N1CCOCC1

2 rings, 11 atoms, the 4-(1,2,5-Thiadiazol-3-yl)morpholine ring system.

48 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H336May cause drowsiness or dizziness.
Precautionary statements (7)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P271Use only outdoors or in a well-ventilated area.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P319Get medical help if you feel unwell.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

(R)-Timolol suppliers

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(R)-Timolol price

Indicative price range per kg from live supplier offers

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Uses and applications

What the substance is used for, by industry and function

Applications are not documented for this substance yet. Suppliers often describe uses on their product pages, linked in the suppliers list above.

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code (R)-Timolol is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for (R)-Timolol is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about (R)-Timolol, based on the data on this page

What is (R)-Timolol?

(R)-timolol is the (R)-(+) (less active) enantiomer of timolol. It is an enantiomer of a (S)-timolol (anhydrous).

What is the CAS number of (R)-Timolol?

The CAS registry number of (R)-Timolol is 26839-76-9.

What is the molecular formula and weight of (R)-Timolol?

The molecular formula of (R)-Timolol is C13H24N4O3S and its molar mass is 316.43 g/mol.

Is (R)-Timolol hazardous?

(R)-Timolol carries the GHS signal word "Warning". Main hazards: may cause drowsiness or dizziness. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of (R)-Timolol?

(R)-Timolol is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy (R)-Timolol?

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What is the price of (R)-Timolol?

Suppliers quote (R)-Timolol on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle (R)-Timolol

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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