Resiquimod
Also known as 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol, 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol, R848 compound
Key facts
What buyers check first
- CAS number
- 144875-48-9
- Formula
- C17H22N4O2
- Molar mass
- 314.39 g/mol
- EC number
- 842-607-0
- HS code
- 293399
- Category
- Screening compounds
What is Resiquimod?
Plain description, key identifiers and synonyms
Resiquimod is an imidazoquinoline.
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- 1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
- CAS number
- 144875-48-9 CAS number cross-checked
- EC number
- 842-607-0
- Molecular formula
- C17H22N4O2
- UNII
- V3DMU7PVXF
- MDL number
- MFCD00937759
- InChIKey
- BXNMTOQRYBFHNZ-UHFFFAOYSA-N
- InChI
- InChI=1S/C17H22N4O2/c1-4-23-9-13-20-14-15(21(13)10-17(2,3)22)11-7-5-6-8-12(11)19-16(14)18/h5-8,22H,4,9-10H2,1-3H3,(H2,18,19)
- SMILES (canonical and isomeric)
- CCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
Synonyms
- 1-(4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
- 1-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
- R848 compound
- 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-Imidazo[4,5-c]quinoline-1-ethanol
- 4-Amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol
- resiquimodum
- 1-(4-amino-2-(ethoxymethyl)-1H-imidazo(4,5-c)quinolin-1-yl)-2-methylpropan-2-ol
- Resiquimod (R-848)
- 1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
- Resiquimod (GMP)
- 1-(4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol.
- 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-
- R848, S28463
- 1-[4-amino-2-(ethoxymethyl)imidazo[4,5-c]quinolin-1-yl]-2-methyl-propan-2-ol
- Resiquimod (GMP
- 1H-Imidazo(4,5-c)quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-alpha,alpha-dimethyl-
- ResiquimodR848?
- R848, Resiquimod
- Resiquimod, >=98% (HPLC)
- 1-(4-Amino-2-ethoxymethyl-imidazo[4,5-c]quinolin-1-yl)-2-methyl-propan-2-ol
- alpha-dimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol
- 1-[4-Amino-2-ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-2-methylpropan-2-ol
- 1H-Imidazo[4,5-c]quinoline-1-ethanol, 4-amino-2-(ethoxymethyl)-|A,|A-dimethyl-
- 4-amino-2-ethoxymethyl-alpha,alpha-dimethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
- 4-amino-alpha,alpha-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinolin-1-ethanol
Show all 26 synonymsShow fewer synonyms
- 4-Amino-alpha,alpha-dimethyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinoline-1-ethanol
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 314.39 g/molcalc.Computed value |
|---|---|
| Exact mass | 314.1743 Dacalc.Computed value |
| LogP (octanol/water) | 2.47calc.Computed value |
| Topological polar surface area | 86.19 Ųcalc.Computed value |
| Hydrogen bond donors | 2calc.Computed value |
| Hydrogen bond acceptors | 5calc.Computed value |
| Rotatable bonds | 5calc.Computed value |
| Heavy atoms | 23calc.Computed value |
| Rings | 3calc.Computed value |
| Aromatic rings | 3calc.Computed value |
| Fraction sp3 carbons | 0.41calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 0calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Murcko scaffold
The ring system that remains when every side chain is removed
c1ccc2c(c1)ncc1nc[nH]c12
3 rings, 13 atoms, the Imidazo(4,5-c)quinoline ring system.
153 other chemicals share this scaffoldSafety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Resiquimod suppliers
Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings
- United States, San DiegoUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- ManufacturerUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- China, NanjingUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- China, KowloonUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- China, SuzhouUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- United States, HauppaugeUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- China, ShanghaiUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- China, WuhanUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- United StatesUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
- China, ChengduUnclaimed profileResiquimodGrade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
Where suppliers are based
22 suppliers in 3 countries
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Resiquimod price
Indicative price range per kg from live supplier offers
Suppliers quote this chemical on request. Send one free request and compare quotes side by side.
Uses and applications
What the substance is used for, by industry and function
Industries and functions
Pharmacological actions
- Toll-Like Receptor Agonists
Roles
- anti-HBV agent
- antimicrobial agent
- antineoplastic agent
- antiviral agent
- pharmaceutical
Pharmacology
Resiquimod is an imidazoquinolinamine and Toll-like receptor (TLR) agonist with potential immune response modifying activity. Resiquimod exerts its effect through the TLR signaling pathway by binding to and activating TLR7 and 8 mainly on dendritic cells, macrophages, and B-lymphocytes. This induces the nuclear translocation of the transcription activator NF-kB as well as activation of other transcription factors.
Read more
This may lead to an increase in mRNA levels and subsequent production of cytokines, especially interferon-alpha (INF-a) and other cytokines, thereby enhancing T-helper 1 (Th1) immune responses. In addition, topical application of resiquimod appears to activate Langerhans' cells, leading to an enhanced activation of T-lymphocytes. Due to its immunostimulatory activity, this agent may potentially be useful as a vaccine adjuvant.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Resiquimod is traded under.
Heterocyclic compounds with nitrogen hetero-atom(s) only, other
- Slovenia31.7%
- Italy24.2%
- United States5.0%
* Partner reported figures, a lower bound.
The HS code shown for Resiquimod is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Resiquimod, based on the data on this page
What is Resiquimod?
What is the CAS number of Resiquimod?
What is the molecular formula and weight of Resiquimod?
What is Resiquimod used for?
Is Resiquimod hazardous?
What is the HS code of Resiquimod?
Where can I buy Resiquimod?
What is the price of Resiquimod?
Guides for buyers
Practical guides that help when you source, ship or handle Resiquimod
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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