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Murcko scaffold

Imidazo(4,5-c)quinoline scaffold

154 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
13
Chemicals
154
With full pages
16
Scaffold SMILES

c1ccc2c(c1)ncc1nc[nH]c12

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffoldOpen the Imidazo(4,5-c)quinoline page
Murcko scaffold c1ccc2c(c1)ncc1nc[nH]c12

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 154 chemicals

Imiquimod chemical structure, C14H16N4, CAS 99011-02-6
Imiquimod
CAS 99011-02-6C14H16N4
4-Amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol chemical structure, C14H16N4O, CAS 112668-45-8
4-Amino-alpha,alpha-dimethyl-1H-imidazo(4,5-c)quinolin-1-ethanol
CAS 112668-45-8C14H16N4O
Resiquimod chemical structure, C17H22N4O2, CAS 144875-48-9
Resiquimod
CAS 144875-48-9C17H22N4O2
4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline chemical structure, C14H14ClN3, CAS 99010-64-7
4-Chloro-1-isobutyl-1H-imidazo[4,5-c]quinoline
CAS 99010-64-7C14H14ClN3
tert-Butyl 4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butylcarbamate chemical structure, C19H25N5O2, CAS 210303-99-4
tert-Butyl 4-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)butylcarbamate
CAS 210303-99-4C19H25N5O2
O-Desethyl resiquimod chemical structure, C15H18N4O2, CAS 144875-23-0
O-Desethyl resiquimod
CAS 144875-23-0C15H18N4O2
N-{2-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide chemical structure, C18H25N5O3S, CAS 642473-62-9
N-{2-[4-Amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]-1,1-dimethylethyl}methanesulfonamide
CAS 642473-62-9C18H25N5O3S
4-Amino-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanol chemical structure, C15H18N4O, CAS 144875-29-6
4-Amino-1-(2-methylpropyl)-1H-imidazo[4,5-c]quinoline-2-methanol
CAS 144875-29-6C15H18N4O
4-Amino-alpha,alpha,2-trimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol chemical structure, C15H18N4O, CAS 151751-58-5
4-Amino-alpha,alpha,2-trimethyl-1H-imidazo(4,5-c)quinoline-1-ethanol
CAS 151751-58-5C15H18N4O
tert-Butyl N-[2-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]carbamate chemical structure, C17H21N5O2, CAS 313350-16-2
tert-Butyl N-[2-(4-amino-1H-imidazo[4,5-c]quinolin-1-yl)ethyl]carbamate
CAS 313350-16-2C17H21N5O2
1-(4-Amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol chemical structure, C16H20N4O, CAS 149876-23-3
1-(4-Amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
CAS 149876-23-3C16H20N4O
1-Butyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinolin-4-amine chemical structure, C17H22N4O, CAS 165120-44-5
1-Butyl-2-ethoxymethyl-1H-imidazo[4,5-c]quinolin-4-amine
CAS 165120-44-5C17H22N4O
2-(1H-Imidazo[4,5-c]quinolin-1-yl)ethanol chemical structure, C12H11N3O, CAS 99010-25-0
2-(1H-Imidazo[4,5-c]quinolin-1-yl)ethanol
CAS 99010-25-0C12H11N3O
tert-Butyl 3-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propylcarbamate chemical structure, C21H29N5O3, CAS 1026925-29-0
tert-Butyl 3-[4-amino-2-(ethoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl]propylcarbamate
CAS 1026925-29-0C21H29N5O3
1-(4-Amino-2-(methoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol chemical structure, C16H20N4O2, CAS 144875-24-1
1-(4-Amino-2-(methoxymethyl)-1H-imidazo[4,5-c]quinolin-1-yl)-2-methylpropan-2-ol
CAS 144875-24-1C16H20N4O2
tert-Butyl [3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]carbamate chemical structure, C22H31N5O2, CAS 1026263-11-5
tert-Butyl [3-(4-amino-2-butyl-1H-imidazo[4,5-c]quinolin-1-yl)propyl]carbamate
CAS 1026263-11-5C22H31N5O2
1H-Imidazo[4,5-c]quinoline-4-carbonitrile, 1-(2-methylpropyl)- chemical structure, C15H14N4, CAS 652976-44-8
1H-Imidazo[4,5-c]quinoline-4-carbonitrile, 1-(2-methylpropyl)-
CAS 652976-44-8C15H14N4
1H-Imidazo[4,5-c]quinolin-4-amine, 2-ethyl-1-[5-(methylsulfonyl)pentyl]- chemical structure, C18H24N4O2S, CAS 434285-67-3
1H-Imidazo[4,5-c]quinolin-4-amine, 2-ethyl-1-[5-(methylsulfonyl)pentyl]-
CAS 434285-67-3C18H24N4O2S
N-(4-(4-Amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide chemical structure, C17H23N5O2S, CAS 532959-63-0
N-(4-(4-Amino-2-ethyl-1H-imidazo(4,5c)quinolin-1-yl)butyl)methanesulfonamide
CAS 532959-63-0C17H23N5O2S
tert-Butyl 3-(4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl)propylcarbamate chemical structure, C21H29N5O3, CAS 908368-40-1
tert-Butyl 3-(4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl)propylcarbamate
CAS 908368-40-1C21H29N5O3
tert-Butyl 2-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]ethylcarbamate chemical structure, C20H27N5O3, CAS 1026339-11-6
tert-Butyl 2-[4-amino-2-(2-methoxyethyl)-1H-imidazo[4,5-c]quinolin-1-yl]ethylcarbamate
CAS 1026339-11-6C20H27N5O3
TLR7/8 agonist 3 chemical structure, C17H23N5O, CAS 642473-95-8
TLR7/8 agonist 3
CAS 642473-95-8C17H23N5O
1-(1-Methylethyl)-1H-imidazo[4,5-c]quinolin-4-amine chemical structure, C13H14N4, CAS 853792-82-2
1-(1-Methylethyl)-1H-imidazo[4,5-c]quinolin-4-amine
CAS 853792-82-2C13H14N4
1H-Imidazo[4,5-c]quinolin-4-amine, 2-ethyl-1-(2-methylpropyl)- chemical structure, C16H20N4, CAS 149876-20-0
1H-Imidazo[4,5-c]quinolin-4-amine, 2-ethyl-1-(2-methylpropyl)-
CAS 149876-20-0C16H20N4