Resolvin E1
Also known as RvE1, 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid, (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid
Key facts
What buyers check first
- CAS number
- 552830-51-0
- Formula
- C20H30O5
- Molar mass
- 350.46 g/mol
- HS code
- 291819
- Category
- Aliphatic and alicyclic building blocks
What is Resolvin E1?
Plain description, key identifiers and synonyms
Resolvin E1 is a resolvin that is (6Z,8E,10E,14Z,16E)-icosa-6,8,10,14,16-pentaenoic acid which is substituted at positions 5, 12 and 18 by hydroxy groups (the 5S,12R,18R stereoisomer). It has a role as an anti-inflammatory agent and a human xenobiotic metabolite. It is a resolvin, a hydroxy polyunsaturated fatty acid, a long-chain fatty acid, a triol and a nonclassic icosanoid. It is a conjugate acid of a resolvin E1(1-).
Identifiers
Registry numbers, names and line notations, tap to copy
- IUPAC name
- (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid
- CAS number
- 552830-51-0Other or deprecated CAS: 1309610-43-2
- Molecular formula
- C20H30O5
- UNII
- GND3JH08JA
- InChIKey
- AOPOCGPBAIARAV-OTBJXLELSA-N
- InChI
- InChI=1S/C20H30O5/c1-2-17(21)11-8-5-9-14-18(22)12-6-3-4-7-13-19(23)15-10-16-20(24)25/h3-9,11-13,17-19,21-23H,2,10,14-16H2,1H3,(H,24,25)/b4-3+,9-5-,11-8+,12-6+,13-7-/t17-,18+,19-/m1/s1
- Canonical SMILES
- CCC(O)C=CC=CCC(O)C=CC=CC=CC(O)CCCC(=O)O
- Isomeric SMILES
- CC[C@H](/C=C/C=C\C[C@H](/C=C/C=C/C=C\[C@H](CCCC(=O)O)O)O)O
Synonyms
- RvE1
- 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-eicosapentaenoic acid
- (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid
- (5S,6Z,8E,10E,12R,14Z,16E,18R)-5,12,18-Trihydroxy-6,8,10,14,16-eicosapentaenoic acid
- 5S,12R,18R-trihydroxy-6Z,8E,10E,14Z,16E-EPA
- 6,8,10,14,16-Eicosapentaenoic acid, 5,12,18-trihydroxy-, (5S,6Z,8E,10E,12R,14Z,16E,18R)-
- (5S,12R,18R)-trihydroxy-(6Z,8E,10E,14Z,16E)-icosapentaenoic acid
- (5S,12R,18R)-trihydroxy-(6Z,8E,10E,14Z,16E)-eicosapentaenoic acid
- (6Z,8E,10E,14Z,16E)-5,12,18-trihydroxyicosa-6,8,10,14,16-pentaenoic acid
- 5S,12R,18R-Trihydroxy-EPA
- Resolvin E1 (solution in ethanol)
- Resolvin E1Please see R144690
Physical and chemical properties
Measured values and descriptors computed from the structure
Physical and chemical properties
Measured values, check the supplier specification for your grade
No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.
Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.
Computed descriptors
Calculated from the structure, useful for screening and formulation
| Molecular weight | 350.46 g/molcalc.Computed value |
|---|---|
| Exact mass | 350.2093 Dacalc.Computed value |
| LogP (octanol/water) | 2.91calc.Computed value |
| Topological polar surface area | 97.99 Ųcalc.Computed value |
| Hydrogen bond donors | 4calc.Computed value |
| Hydrogen bond acceptors | 4calc.Computed value |
| Rotatable bonds | 13calc.Computed value |
| Heavy atoms | 25calc.Computed value |
| Rings | 0calc.Computed value |
| Aromatic rings | 0calc.Computed value |
| Fraction sp3 carbons | 0.45calc.Computed value |
| Formal charge | 0calc.Computed value |
| Stereocentres | 3calc.Computed value |
| Lipinski rule of five | Passes (0 violations)calc.Computed value |
Calculated for screening. Confirm critical figures with the supplier.
Safety and hazards
GHS classification summary, not a safety data sheet
No GHS hazard classification is recorded for this substance yet. That does not mean it is harmless.
GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.
Resolvin E1 suppliers
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- United States, San DiegoUnclaimed profileResolvin E1Grade, purity and minimum order on requestPrice on request
Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.
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1 supplier in 1 country
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Resolvin E1 price
Indicative price range per kg from live supplier offers
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Uses and applications
What the substance is used for, by industry and function
Industries and functions
Roles
- animal metabolite
- anti-inflammatory agent
- eukaryotic metabolite
- human metabolite
- human xenobiotic metabolite
- mammalian metabolite
- metabolite
- xenobiotic metabolite
Pharmacology
Resolvin E1 is a polyunsaturated fatty acid in the resolvin family that is a poly-hydroxyl metabolite of docosahexaenoic acid (DHA), with potential analgesic and anti-inflammatory activities.
Regulatory status
Inventories, regulations and trade controls that list this substance
No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.
HS code and trade data
Customs classification and reported world trade statistics
Global trade
World import and export statistics for the HS code Resolvin E1 is traded under.
Carboxylic acids with alcohol function but without other oxygen function, their…
- Germany11.7%
- South Korea9.8%
- Italy9.6%
* Partner reported figures, a lower bound.
The HS code shown for Resolvin E1 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.
Frequently asked questions
Quick answers about Resolvin E1, based on the data on this page
What is Resolvin E1?
What is the CAS number of Resolvin E1?
What is the molecular formula and weight of Resolvin E1?
What is Resolvin E1 used for?
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What is the HS code of Resolvin E1?
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Guides for buyers
Practical guides that help when you source, ship or handle Resolvin E1
- Guide, Chemical identityCAS registry numbers explainedWhat a CAS number identifies, how the check digit works, why one chemical can have several numbers and what a CAS number cannot tell you about a product.Read
- Article, SourcingHow to write an RFQ that gets fast and accurate quotesWhat suppliers need to quote quickly and comparably: exact product identity, quantity and packing, delivery terms, documents, samples and payment, with a ready to use template.Read
- Guide, Trade and logisticsHS codes for chemicals and why they matterHow the Harmonized System classifies chemicals, the chapters that matter, the rules for chemically defined compounds and mixtures, and practical steps to find the right code.Read
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