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Emulsifiers

Span 40

Also known as Sorbitan monopalmitate, Arlacel 40, Palmitate de sorbitan

CAS 26266-57-9Formula C22H42O6Molar mass 402.57 g/molEC 247-568-8
GHS signal word: Warning. Pictograms: Harmful or irritant 33 suppliers listed
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Span 40 chemical structure, C22H42O6, CAS 26266-57-9
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
26266-57-9
Formula
C22H42O6
Physical form
Pellets
Solubility
Soluble at temperatures above its melting point in ethanol, methanol, ether, ethyl acetaโ€ฆ
HS code
293219
Category
Emulsifiers
Illustrative photo, closed jumbo bulk bags in a warehouse in a warehouse
Typical packagingIllustrative packaging image, not the actual product

What is Span 40?

Plain description, key identifiers and synonyms

Sorbitan monopalmitate is a fatty acid ester.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
[(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] hexadecanoate
CAS number
26266-57-9
EC number
247-568-8
Molecular formula
C22H42O6
UNII
77K6Z421KU
INCI name
SORBITAN PALMITATE
InChIKey
IYFATESGLOUGBX-YVNJGZBMSA-N
InChI
InChI=1S/C22H42O6/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-20(25)27-17-19(24)22-21(26)18(23)16-28-22/h18-19,21-24,26H,2-17H2,1H3/t18-,19+,21+,22+/m0/s1
Canonical SMILES
CCCCCCCCCCCCCCCC(=O)OCC(O)C1OCC(O)C1O
Isomeric SMILES
CCCCCCCCCCCCCCCC(=O)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O

Synonyms

  • Sorbitan monopalmitate
  • Arlacel 40
  • Palmitate de sorbitan
  • Sorbitani palmitas
  • Sorbitan palmitate
  • Sorbitan, monohexadecanoate
  • INS NO.495
  • D-Glucitol, 1,4-anhydro-, 6-hexadecanoate
  • 1,4-Anhydro-D-glucitol, 6-hexadecanoate
  • 2-(3,4-dihydroxyoxolan-2-yl)-2-hydroxyethyl hexadecanoate
  • Sorbitan monohexadecanoate
  • Glycomul P
  • Liposorb P
  • Protachem SMP
  • Sorbitan palmitas
  • Crill 2
  • Montane 40
  • Nikkol SP10
  • Nonion PP40
  • Sorgen 70
  • Nissan nonion PP40
  • Rheodol SP-P 10
  • Sorbitan, monopalmitate
  • Emsorb 2510
  • Nissan nonion PP 40R
Show all 31 synonyms
  • [(2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl] hexadecanoate
  • Palmitato de sorbitano
  • Span 40 (=Sorbitan Monopalmitate)
  • Palmitato de sorbitan
  • (2R)-2-[(2R,3R,4S)-3,4-dihydroxyoxolan-2-yl]-2-hydroxyethyl hexadecanoate
  • (R)-2-((2R,3R,4S)-3,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl palmitate

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

Physical form
Pelletsexp.
Solubility
Soluble at temperatures above its melting point in ethanol, methanol, ether, ethyl acetate, aniline, toluene, dioxane, petroleum ether and carbon tetrachloride. Insoluble in cold water but dispersible in warm waterexp.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
402.57 g/molcalc.
Exact mass
402.2981 Dacalc.
LogP (octanol/water)
3.49calc.
Topological polar surface area
96.22 ร…ยฒcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
6calc.
Rotatable bonds
17calc.
Heavy atoms
28calc.
Rings
1calc.
Aromatic rings
0calc.
Fraction sp3 carbons
0.96calc.
Formal charge
0calc.
Stereocentres
4calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, C1CCOC1

C1CCOC1

1 ring, 5 atoms, the Tetrahydrofuran ring system.

8,114 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H315Causes skin irritation.
  • H319Causes serious eye irritation.
  • H335May cause respiratory irritation.
Precautionary statements (16)
  • P261Avoid breathing dust, fume, gas, mist, vapours or spray.
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P271Use only outdoors or in a well-ventilated area.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P302 + P352If on skin: Wash with plenty of water.
  • P304 + P340If inhaled: Remove person to fresh air and keep comfortable for breathing.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P319Get medical help if you feel unwell.
  • P321Specific treatment (see supplemental first aid instructions on the label).
  • P332 + P317If skin irritation occurs: Get medical help.
  • P337 + P317If eye irritation persists: Get medical help.
  • P362 + P364Take off contaminated clothing. And wash it before reuse.
  • P403 + P233Store in a well-ventilated place. Keep container tightly closed.
  • P405Store locked up.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Span 40 suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 33 suppliers
30 of 30 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

33 suppliers in 11 countries

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Span 40 price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Industrial uses: Adhesion/cohesion promoter, Intermediate, Emulsifier, Surfactant (surface active agent).

Consumer uses: Surfactant (surface active agent), Emulsifier.

Use classes: Surfactants, Safer Chemical Classes, Food additives, Cosmetics.

Cosmetic ingredient, INCI name SORBITAN PALMITATE(surfactant - emulsifying)

Functional uses

  • Dispersing agent
  • Emulsifier
  • Surfactant (surface active agent)
  • Wetting agent (non-aqueous)

Cosmetic functions

  • Surfactant - emulsifying

Regulatory status

Inventories, regulations and trade controls that list this substance

Health and food

  • EU cosmetic ingredient inventory
  • Food additive

United States

  • Safer Choice ingredient list (USA)
  • TSCA inventory (USA)
    Status: Active in US commerce

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Span 40 is traded under.

HS 2932.19Indicative HS code

Compounds containing an unfused furan ring (whether or not hydrogenated) in theโ€ฆ

World exports in 2024
$2.62B
โˆ’6.4% vs 2023, imports $2.56B
2019 to 2024
Top exporters
  1. Germany57.9%
  2. Italy11.5%
  3. China10.4%
Top importers
  1. Greece40.4%
  2. Japan16.3%
  3. Germany12.8%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Span 40 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Span 40, based on the data on this page

What is Span 40?

Sorbitan monopalmitate is a fatty acid ester.

What is the CAS number of Span 40?

The CAS registry number of Span 40 is 26266-57-9.

What is the molecular formula and weight of Span 40?

The molecular formula of Span 40 is C22H42O6 and its molar mass is 402.57 g/mol.

What is Span 40 used for?

Industrial uses: Adhesion/cohesion promoter, Intermediate, Emulsifier, Surfactant (surface active agent). Consumer uses: Surfactant (surface active agent), Emulsifier. Use classes: Surfactants, Safer Chemical Classes, Food additives, Cosmetics.

Is Span 40 hazardous?

Span 40 carries the GHS signal word "Warning". Main hazards: causes skin irritation, causes serious eye irritation, may cause respiratory irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Span 40?

Span 40 is usually classified under HS code 293219 (Compounds containing an unfused furan ring (whether or not hydrogenated) in theโ€ฆ). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Span 40?

CompoundList lists 33 suppliers of Span 40 in China, India, United States, Germany and 7 more. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

Where can I buy Span 40 in India?

7 suppliers in India list Span 40 on CompoundList. Filter the suppliers list by country and send a request to compare prices, grades and delivery times.

What is the price of Span 40?

Suppliers quote Span 40 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Span 40

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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