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Heterocyclic building blocks

Tpca-1

Also known as IKK-2 Inhibitor IV, TPCA1, 2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide

CAS 507475-17-4Formula C12H10FN3O2SMolar mass 279.30 g/molEC 637-136-0
GHS signal word: Warning. Pictograms: Harmful or irritant 12 suppliers listed
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Tpca-1 chemical structure, C12H10FN3O2S, CAS 507475-17-4
2D chemical structure

Key facts

What buyers check first

All properties
CAS number
507475-17-4
Formula
C12H10FN3O2S
Molar mass
279.30 g/mol
EC number
637-136-0
HS code
293499
Category
Heterocyclic building blocks

What is Tpca-1?

Plain description, key identifiers and synonyms

2-(carbamoylamino)-5-(4-fluorophenyl)-3-thiophenecarboxamide is a member of thiophenes and an aromatic amide.

Identifiers

Registry numbers, names and line notations, tap to copy

IUPAC name
2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
CAS number
507475-17-4 CAS number cross-checked
EC number
637-136-0
Molecular formula
C12H10FN3O2S
UNII
9M632G86CC
MDL number
MFCD09037541
InChIKey
SAYGKHKXGCPTLX-UHFFFAOYSA-N
InChI
InChI=1S/C12H10FN3O2S/c13-7-3-1-6(2-4-7)9-5-8(10(14)17)11(19-9)16-12(15)18/h1-5H,(H2,14,17)(H3,15,16,18)
SMILES (canonical and isomeric)
C1=CC(=CC=C1C2=CC(=C(S2)NC(=O)N)C(=O)N)F

Synonyms

  • IKK-2 Inhibitor IV
  • TPCA1
  • 2-(carbamoylamino)-5-(4-fluorophenyl)thiophene-3-carboxamide
  • IKK 2 Inhibitor IV
  • 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • 2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide
  • 3-Thiophenecarboxamide, 2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-
  • 3-Thiophenecarboxamide, 2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-
  • 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxamide
  • [5-(p-Fluorophenyl)-2-ureido]thiophene-3-carboxamide
  • 5-(4-fluorophenyl)-2-ureido-thiophene-3-carboxamide
  • 5-(4-fluorophenyl)-2-ureido-thiophene-3 carboxylic acid amide
  • 3qfv
  • TPCA 1
  • TPCA-1?
  • 3-thiophenecarboxamide,2-((aminocarbonyl)amino)-5-(4-fluorophenyl)-
  • Sdccgsbi-0086762.p004
  • TPCA-1, >=95% (HPLC)
  • 5-(4-Fluorophenyl)-2-ureidothiophene-3-carboxylic acid amide
  • 5-(4-luorophenyl)-2-ureidothiophene-3-carboxylic acid amide
  • 5-(4-fluoro-phenyl)-2-ureido-thiophene-3-carboxylic acid amide

Physical and chemical properties

Measured values and descriptors computed from the structure

Physical and chemical properties

Measured values, check the supplier specification for your grade

No measured properties are recorded for this substance yet. Ask suppliers for a technical data sheet.

Values vary by grade. Ask suppliers for the COA or TDS of the batch you buy.

Computed descriptors

Calculated from the structure, useful for screening and formulation

Molecular weight
279.30 g/molcalc.
Exact mass
279.0478 Dacalc.
LogP (octanol/water)
2.14calc.
Topological polar surface area
98.21 Ųcalc.
Hydrogen bond donors
3calc.
Hydrogen bond acceptors
3calc.
Rotatable bonds
3calc.
Heavy atoms
19calc.
Rings
2calc.
Aromatic rings
2calc.
Fraction sp3 carbons
0calc.
Formal charge
0calc.
Stereocentres
0calc.
Lipinski rule of five
Passes (0 violations)calc.

Calculated for screening. Confirm critical figures with the supplier.

Murcko scaffold

The ring system that remains when every side chain is removed

Murcko scaffold of this chemical, c1ccc(-c2cccs2)cc1

c1ccc(-c2cccs2)cc1

2 rings, 11 atoms, the 2-Phenylthiophene ring system.

2,426 other chemicals share this scaffold

Safety and hazards

GHS classification summary, not a safety data sheet

GHS signal word
Warning
GHS07: Harmful or irritant
Harmful or irritant

Hazard statements

  • H302Harmful if swallowed.
  • H319Causes serious eye irritation.
Precautionary statements (9)
  • P264Wash skin thoroughly after handling.
  • P264 + P265Wash skin thoroughly after handling. Do not touch eyes.
  • P270Do not eat, drink or smoke when using this product.
  • P280Wear protective gloves, protective clothing, eye protection and face protection.
  • P301 + P317If swallowed: Get medical help.
  • P305 + P351 + P338If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P330Rinse mouth.
  • P337 + P317If eye irritation persists: Get medical help.
  • P501Dispose of contents and container in accordance with local regulations.

GHS classification summary, not a safety data sheet (SDS). Classifications can differ by supplier, grade and concentration. Always check the supplier's SDS.

Full safety data and first aid

Tpca-1 suppliers

Sponsored listings first, then the documented ranking: membership, verification, replies, completeness, freshness and ratings

All 12 suppliers
12 of 12 offers

Suppliers marked Unclaimed profile have not claimed their profile yet. They are not verified by CompoundList, their offers are price on request and details may have changed, so please confirm them with the supplier. Company representatives can claim a profile with a business email on the company's own website domain. Our team verifies each claim and sends the result by email.

Where suppliers are based

12 suppliers in 3 countries

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Tpca-1 price

Indicative price range per kg from live supplier offers

No published prices right now

Suppliers quote this chemical on request. Send one free request and compare quotes side by side.

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Uses and applications

What the substance is used for, by industry and function

Pharmacological actions

  • Protein Kinase Inhibitors

Regulatory status

Inventories, regulations and trade controls that list this substance

No regulatory list memberships are recorded for this substance yet. Always check the rules of the importing and exporting country before trade.

HS code and trade data

Customs classification and reported world trade statistics

Global trade

World import and export statistics for the HS code Tpca-1 is traded under.

HS 2934.99Indicative HS code

Nucleic acids and their salts, other heterocyclic compounds, not elsewhere classified in heading 2934

World exports in 2024
$26.7B
+15.0% vs 2023, imports $26.3B
2019 to 2024
Top exporters
  1. Ireland26.3%
  2. China15.7%
  3. Singapore10.3%
Top importers
  1. United States24.5%
  2. Germany23.1%
  3. Japan4.5%
Reported customs values in USD, not prices.Full trade data

The HS code shown for Tpca-1 is indicative (it was assigned by structure rules). Confirm the classification with your customs broker before shipping.

Frequently asked questions

Quick answers about Tpca-1, based on the data on this page

What is Tpca-1?

2-(carbamoylamino)-5-(4-fluorophenyl)-3-thiophenecarboxamide is a member of thiophenes and an aromatic amide.

What is the CAS number of Tpca-1?

The CAS registry number of Tpca-1 is 507475-17-4.

What is the molecular formula and weight of Tpca-1?

The molecular formula of Tpca-1 is C12H10FN3O2S and its molar mass is 279.30 g/mol.

What is Tpca-1 used for?

Known uses and roles of Tpca-1 include building blocks in research and laboratory, screening compounds in research and laboratory, biochemical and pharmacological tools in research and laboratory and protein kinase inhibitors.

Is Tpca-1 hazardous?

Tpca-1 carries the GHS signal word "Warning". Main hazards: harmful if swallowed, causes serious eye irritation. This summary is not an SDS, always read the supplier safety data sheet.

What is the HS code of Tpca-1?

Tpca-1 is usually classified under HS code 293499 (Nucleic acids and their salts, whether or not chemically defined, other heterocyclic…). This is indicative, confirm it with your customs broker before shipping.

Where can I buy Tpca-1?

CompoundList lists 12 suppliers of Tpca-1 in China, United States and Canada. Send one free request to get and compare quotes. Your contact details stay private until you accept a quote.

What is the price of Tpca-1?

Suppliers quote Tpca-1 on request because prices depend on grade, purity, quantity and destination. A free request on CompoundList gets you several quotes to compare.

Guides for buyers

Practical guides that help when you source, ship or handle Tpca-1

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Data last updated 7 Oct 2026. Details may have changed, please confirm them with the supplier. Report an error on this page
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