Murcko scaffold
Ring system with 2 rings and 12 atoms
25 chemicals on CompoundList share this ring system.
- Rings
- 2
- Scaffold atoms
- 12
- Chemicals
- 25
- With full pages
- 1
Scaffold SMILES
c1ccc(Nc2ccsc2)cc1
A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.
Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.
Chemicals with this scaffold
Open one to see its structure, properties and suppliers.
Showing 1 to 25 of 25 chemicals
Eltenac
CAS 72895-88-6C12H9Cl2NO2S
4-N-Methyl-N-phenylaminothiophene-3-carboxylic acid
CAS 107947-00-2C12H11NO2S
Aclantate
CAS 39633-62-0C15H14ClNO4S
4-(N-(2-Chloro-3-methylphenyl)amino)thiophene-3-carboxylic acid
CAS 16563-09-0C12H10ClNO2S
Clantifen
CAS 16562-98-4C11H7Cl2NO2S
![Methyl 4-[(2-amino-4-fluorophenyl)amino]-3-thiophenecarboxylate chemical structure, C12H11FN2O2S, CAS 69363-86-6](/s/BQVJMDNIODLEBD-UHFFFAOYSA-N.svg)
Methyl 4-[(2-amino-4-fluorophenyl)amino]-3-thiophenecarboxylate
CAS 69363-86-6C12H11FN2O2S
Methyl 3-(2-aminoanilino)thiophene-2-carboxylate
CAS 61325-18-6C12H12N2O2S
Methyl 4-(2-aminoanilino)thiophene-3-carboxylate
CAS 61325-25-5C12H12N2O2S
![4-[4-(Methylsulfanyl)-2-nitroanilino]thiophene-3-carbonitrile chemical structure, C12H9N3O2S2, CAS 61325-11-9](/s/XISINPRKNHQEPT-UHFFFAOYSA-N.svg)
4-[4-(Methylsulfanyl)-2-nitroanilino]thiophene-3-carbonitrile
CAS 61325-11-9C12H9N3O2S2
4-Amino-3-anilino-5-nitrothiophene-2-carbonitrile
CAS 88096-56-4C11H8N4O2S
N-Phenyl-N-thiophen-3-yl-acetamide
CAS 227805-39-2C12H11NOS
N-(4-Methoxyphenyl)thiophen-3-amine
CAS 937646-26-9C11H11NOS
Methyl 3-(2-nitroanilino)thiophene-2-carboxylate
CAS 61324-85-4C12H10N2O4S
4-(2-Amino-4-chloroanilino)thiophene-3-carbonitrile
CAS 61325-31-3C11H8ClN3S
4-(2,6-Dichloroanilino)-3-thiophenemethanol
CAS 72888-37-0C11H9Cl2NOS
4-(2,6-Dichloroanilino)-3-thiopheneacetonitrile
CAS 72888-00-7C12H8Cl2N2S
![4-[(2,6-Dichlorophenyl)amino]-5-methyl-3-thiophenemethanol chemical structure, C12H11Cl2NOS, CAS 72888-42-7](/s/KKJHKZJSSCRREC-UHFFFAOYSA-N.svg)
4-[(2,6-Dichlorophenyl)amino]-5-methyl-3-thiophenemethanol
CAS 72888-42-7C12H11Cl2NOS
4-Anilino-2-methylthiophene-3-carboxylic acid
CAS 1170983-53-5C12H11NO2S
4-(3-Trifluoromethyl-phenylamino)-thiophene-3-carboxylic acid methyl ester
CAS 1029773-36-1C13H10F3NO2S
4-(2,6-Dichloroanilino)-3-thiophenecarboxylic Acid Methyl Ester
CAS 72888-20-1C12H9Cl2NO2S
6-Methyl-N1-(3-thienyl)benzene-1,3-diamine
CAS 1525224-04-7C11H12N2S
![Methyl 4-[(2-fluoro-4-iodophenyl)amino]thiophene-3-carboxylate chemical structure, C12H9FINO2S, CAS 934665-96-0](/s/HPIIYIZJKRIUTE-UHFFFAOYSA-N.svg)
Methyl 4-[(2-fluoro-4-iodophenyl)amino]thiophene-3-carboxylate
CAS 934665-96-0C12H9FINO2S
![4-[(2-Fluoro-4-iodophenyl)amino]thiophene-3-carboxylic acid chemical structure, C11H7FINO2S, CAS 934665-97-1](/s/NENIEKNUHOAGLD-UHFFFAOYSA-N.svg)
4-[(2-Fluoro-4-iodophenyl)amino]thiophene-3-carboxylic acid
CAS 934665-97-1C11H7FINO2S
![3-[(Thiophen-3-yl)amino]phenol chemical structure, C10H9NOS, CAS 1198117-55-3](/s/ZHWAHSHHIYRKLF-UHFFFAOYSA-N.svg)
3-[(Thiophen-3-yl)amino]phenol
CAS 1198117-55-3C10H9NOS
Related scaffolds
Same ring framework with different atoms or bond orders
c1ccc(Cn2cccn2)cc1271 chemicals
c1ccc(CN2CCCC2)cc1172 chemicals
O=S(=O)(c1ccccc1)N1CCCC1146 chemicals
c1ccc(Cn2ccnc2)cc1107 chemicals![Scaffold c1ccc(N=c2[nH]ccs2)cc1](/scaffold/OGVGQYZRJXSMGC-UHFFFAOYSA-N/structure.svg)
c1ccc(N=c2[nH]ccs2)cc198 chemicals
O=C1NC(=S)SC1=Cc1ccccc186 chemicals
O=C(c1ccccc1)N1CCCC186 chemicals
O=S(=O)(c1ccccc1)n1ccnc184 chemicals![Scaffold O=C(c1ccccc1)c1cc[nH]c1](/scaffold/DSNSKSWTLGZGAN-UHFFFAOYSA-N/structure.svg)
O=C(c1ccccc1)c1cc[nH]c177 chemicals
c1ccc(Cn2ccnn2)cc177 chemicals
c1ccc(Cc2cncs2)cc175 chemicals
c1ccc(Cn2cccc2)cc163 chemicals