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Murcko scaffold

Ring system with 3 rings and 17 atoms

25 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
25
With full pages
7
Scaffold SMILES

c1ccc2c(CC3CCCCN3)ccnc2c1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1ccc2c(CC3CCCCN3)ccnc2c1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 25 of 25 chemicals

Mefloquine chemical structure, C17H16F6N2O, CAS 53230-10-7
Mefloquine
CAS 53230-10-7C17H16F6N2O
(-)-Mefloquine chemical structure, C17H16F6N2O, CAS 51742-87-1
(-)-Mefloquine
CAS 51742-87-1C17H16F6N2O
Mefloquine hydrochloride chemical structure, C17H17ClF6N2O, CAS 51773-92-3
Mefloquine hydrochloride
CAS 51773-92-3C17H17ClF6N2O
Fansimef chemical structure, C41H44Cl2F6N10O5S, CAS 69191-18-0
Fansimef
CAS 69191-18-0C41H44Cl2F6N10O5S
2-Quinolinecarboxamide, 4-(hydroxy-2-piperidinylmethyl)-8-(trifluoromethyl)- chemical structure, C17H18F3N3O2, CAS 63307-17-5
2-Quinolinecarboxamide, 4-(hydroxy-2-piperidinylmethyl)-8-(trifluoromethyl)-
CAS 63307-17-5C17H18F3N3O2
4-Quinolinemethanol, 8-fluoro-alpha-2-piperidinyl-2-(trifluoromethyl)- chemical structure, C16H16F4N2O, CAS 63307-18-6
4-Quinolinemethanol, 8-fluoro-alpha-2-piperidinyl-2-(trifluoromethyl)-
CAS 63307-18-6C16H16F4N2O
(AS)-rel-a-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride chemical structure, C17H17ClF6N2O, CAS 33433-59-9
(AS)-rel-a-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol monohydrochloride
CAS 33433-59-9C17H17ClF6N2O
(+)-Mefloquine chemical structure, C17H16F6N2O, CAS 51688-68-7
(+)-Mefloquine
CAS 51688-68-7C17H16F6N2O
(6-Chloro-2,8-bis(trifluoromethyl)quinolin-4-yl)(piperidin-2-yl)methanol chemical structure, C17H15ClF6N2O, CAS 959023-53-1
(6-Chloro-2,8-bis(trifluoromethyl)quinolin-4-yl)(piperidin-2-yl)methanol
CAS 959023-53-1C17H15ClF6N2O
(-)-threo-Mefloquine chemical structure, C17H16F6N2O, CAS 51744-84-4
(-)-threo-Mefloquine
CAS 51744-84-4C17H16F6N2O
rel-(alphaR)-alpha-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol chemical structure, C17H16F6N2O, CAS 58737-31-8
rel-(alphaR)-alpha-(2R)-2-Piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol
CAS 58737-31-8C17H16F6N2O
4-Quinolinemethanol, 6,8-dichloro-alpha-(2-piperidyl)-2-(trifluoromethyl)-, methanesulfonate,hemihydrate chemical structure, C17H19Cl2F3N2O4S, CAS 76487-48-4
4-Quinolinemethanol, 6,8-dichloro-alpha-(2-piperidyl)-2-(trifluoromethyl)-, methanesulfonate,hemihydrate
CAS 76487-48-4C17H19Cl2F3N2O4S
(R*,R*)-(2,8-Bis-trifluoromethyl-quinolin-4-yl)-piperidin-2-yl-methanol hydrochloride chemical structure, C17H17ClF6N2O, CAS 58560-52-4
(R*,R*)-(2,8-Bis-trifluoromethyl-quinolin-4-yl)-piperidin-2-yl-methanol hydrochloride
CAS 58560-52-4C17H17ClF6N2O
(S)-[2,8-Bis(trifluoromethyl)quinolin-4-yl][(2S)-piperidin-2-yl]methanol hydrochloride chemical structure, C17H17ClF6N2O, CAS 51744-85-5
(S)-[2,8-Bis(trifluoromethyl)quinolin-4-yl][(2S)-piperidin-2-yl]methanol hydrochloride
CAS 51744-85-5C17H17ClF6N2O
4-Quinolinemethanol, alpha-(2S)-2-piperidinyl-2,8-bis(trifluoromethyl)-, hydrochloride (1:1), (alphaR)- chemical structure, C17H17ClF6N2O, CAS 51744-83-3
4-Quinolinemethanol, alpha-(2S)-2-piperidinyl-2,8-bis(trifluoromethyl)-, hydrochloride (1:1), (alphaR)-
CAS 51744-83-3C17H17ClF6N2O
TCMDC-142228 chemical structure, C16H17ClF4N2O, CAS 31001-40-8
TCMDC-142228
CAS 31001-40-8C16H17ClF4N2O
Piperidin-2-yl(quinolin-4-yl)methanol hydrochloride chemical structure, C15H19ClN2O, CAS 7498-44-4
Piperidin-2-yl(quinolin-4-yl)methanol hydrochloride
CAS 7498-44-4C15H19ClN2O
(R)-[2,8-Bis(trifluoromethyl)quinolin-4-yl](piperidin-2-yl)methanol hydrochloride chemical structure, C17H17ClF6N2O, CAS 2743430-00-2
(R)-[2,8-Bis(trifluoromethyl)quinolin-4-yl](piperidin-2-yl)methanol hydrochloride
CAS 2743430-00-2C17H17ClF6N2O
Mefloquine-d10 hydrochloride chemical structure, C17H17ClF6N2O, CAS 1217653-15-0
Mefloquine-d10 hydrochloride
CAS 1217653-15-0C17H17ClF6N2O
Piperidin-2-yl-(2-propan-2-ylquinolin-4-yl)methanol hydrochloride chemical structure, C18H25ClN2O, CAS 5429-27-6
Piperidin-2-yl-(2-propan-2-ylquinolin-4-yl)methanol hydrochloride
CAS 5429-27-6C18H25ClN2O
Mefloquine mesylate chemical structure, C18H20F6N2O4S, CAS 64003-26-5
Mefloquine mesylate
CAS 64003-26-5C18H20F6N2O4S
(R)-[(2S,4S,5R)-4,5-Diethylpiperidin-2-yl](6-methoxyquinolin-4-yl)methanol chemical structure, C20H28N2O2, CAS 28008-72-2
(R)-[(2S,4S,5R)-4,5-Diethylpiperidin-2-yl](6-methoxyquinolin-4-yl)methanol
CAS 28008-72-2C20H28N2O2
(S)-(2,8-Bis(trifluoromethyl)quinolin-4-yl)((R)-piperidin-2-yl)methanamine chemical structure, C17H17F6N3, CAS 2691082-98-9
(S)-(2,8-Bis(trifluoromethyl)quinolin-4-yl)((R)-piperidin-2-yl)methanamine
CAS 2691082-98-9C17H17F6N3
{(2S,4S)-4-[(2R)-Butan-2-yl]piperidin-2-yl}(6-methoxyquinolin-4-yl)methanol chemical structure, C20H28N2O2, CAS 28043-35-8
{(2S,4S)-4-[(2R)-Butan-2-yl]piperidin-2-yl}(6-methoxyquinolin-4-yl)methanol
CAS 28043-35-8C20H28N2O2