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Murcko scaffold

Ring system with 2 rings and 14 atoms

14 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
14
Chemicals
14
With full pages
3
Scaffold SMILES

O=C(Cc1ccccc1)N1CCC=N1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Cc1ccccc1)N1CCC=N1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 14 of 14 chemicals

Ethanone, 1-(3,5,5-trimethyl-2-pyrazolin-1-yl)-2-phenyl- chemical structure, C14H18N2O, CAS 380892-04-6
Ethanone, 1-(3,5,5-trimethyl-2-pyrazolin-1-yl)-2-phenyl-
CAS 380892-04-6C14H18N2O
1-[5-Hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone chemical structure, C13H13F3N2O2, CAS 331238-82-5
1-[5-Hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone
CAS 331238-82-5C13H13F3N2O2
1-[5-tert-Butyl-5-hydroxy-3-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone chemical structure, C16H19F3N2O2, CAS 331238-83-6
1-[5-tert-Butyl-5-hydroxy-3-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone
CAS 331238-83-6C16H19F3N2O2
1-[5-(1,1,2,2,3,3,3-Heptafluoropropyl)-5-hydroxy-3-methyl-4H-pyrazol-1-yl]-2-phenylethanone chemical structure, C15H13F7N2O2, CAS 331238-86-9
1-[5-(1,1,2,2,3,3,3-Heptafluoropropyl)-5-hydroxy-3-methyl-4H-pyrazol-1-yl]-2-phenylethanone
CAS 331238-86-9C15H13F7N2O2
1-[3-Ethyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone chemical structure, C14H15F3N2O2, CAS 345259-02-1
1-[3-Ethyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone
CAS 345259-02-1C14H15F3N2O2
1-[3-Ethyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone chemical structure, C14H14F3N3O4, CAS 350613-30-8
1-[3-Ethyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone
CAS 350613-30-8C14H14F3N3O4
1-[5-Hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone chemical structure, C13H12F3N3O4, CAS 312274-76-3
1-[5-Hydroxy-3-methyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone
CAS 312274-76-3C13H12F3N3O4
1-[5-Hydroxy-3-propyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone chemical structure, C15H17F3N2O2, CAS 333771-04-3
1-[5-Hydroxy-3-propyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-phenylethanone
CAS 333771-04-3C15H17F3N2O2
1-[3-Butyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone chemical structure, C16H18F3N3O4, CAS 357441-79-3
1-[3-Butyl-5-hydroxy-5-(trifluoromethyl)-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone
CAS 357441-79-3C16H18F3N3O4
1-(5-Hydroxy-3-methyl-5-pentafluoroethyl-4,5-dihydro-pyrazol-1-yl)-2-(4-nitro-phenyl)-ethanone chemical structure, C14H12F5N3O4, CAS 378212-26-1
1-(5-Hydroxy-3-methyl-5-pentafluoroethyl-4,5-dihydro-pyrazol-1-yl)-2-(4-nitro-phenyl)-ethanone
CAS 378212-26-1C14H12F5N3O4
1-[3,5-Bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-2-(3,4-diethoxyphenyl)ethanone chemical structure, C17H20F4N2O4, CAS 512826-42-5
1-[3,5-Bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-2-(3,4-diethoxyphenyl)ethanone
CAS 512826-42-5C17H20F4N2O4
1-[3,5-Bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-2-(3,4-dichlorophenyl)ethanone chemical structure, C13H10Cl2F4N2O2, CAS 438227-46-4
1-[3,5-Bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-2-(3,4-dichlorophenyl)ethanone
CAS 438227-46-4C13H10Cl2F4N2O2
2-(3,4-Dimethoxyphenyl)-1-[5-hydroxy-3-propyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]ethanone chemical structure, C17H21F3N2O4, CAS 312533-24-7
2-(3,4-Dimethoxyphenyl)-1-[5-hydroxy-3-propyl-5-(trifluoromethyl)-4H-pyrazol-1-yl]ethanone
CAS 312533-24-7C17H21F3N2O4
1-[3,5-Bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone chemical structure, C13H11F4N3O4, CAS 522635-92-3
1-[3,5-Bis(difluoromethyl)-5-hydroxy-4H-pyrazol-1-yl]-2-(4-nitrophenyl)ethanone
CAS 522635-92-3C13H11F4N3O4