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Murcko scaffold

Ring system with 3 rings and 16 atoms

7 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
16
Chemicals
7
With full pages
1
Scaffold SMILES

O=C1NCc2nccc(-c3ccccc3)c21

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1NCc2nccc(-c3ccccc3)c21

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 7 of 7 chemicals

Bms-767778 chemical structure, C19H20Cl2N4O2, CAS 915729-95-2
Bms-767778
CAS 915729-95-2C19H20Cl2N4O2
tert-Butyl (4-(2,4-dichlorophenyl)-6-(2-(dimethylamino)-2-oxoethyl)-2-methyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)methylcarbamate chemical structure, C24H28Cl2N4O4, CAS 915731-88-3
tert-Butyl (4-(2,4-dichlorophenyl)-6-(2-(dimethylamino)-2-oxoethyl)-2-methyl-5-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyridin-3-yl)methylcarbamate
CAS 915731-88-3C24H28Cl2N4O4
4-(2,4-Dichlorophenyl)-5,7-dihydro-3-(hydroxymethyl)-N,N,2-trimethyl-5-oxo-6H-pyrrolo[3,4-b]pyridine-6-acetamide chemical structure, C19H19Cl2N3O3, CAS 1181232-28-9
4-(2,4-Dichlorophenyl)-5,7-dihydro-3-(hydroxymethyl)-N,N,2-trimethyl-5-oxo-6H-pyrrolo[3,4-b]pyridine-6-acetamide
CAS 1181232-28-9C19H19Cl2N3O3
3-(Chloromethyl)-4-(2,4-dichlorophenyl)-5,7-dihydro-N,N,2-trimethyl-5-oxo-6H-pyrrolo[3,4-b]pyridine-6-acetamide chemical structure, C19H18Cl3N3O2, CAS 1174538-59-0
3-(Chloromethyl)-4-(2,4-dichlorophenyl)-5,7-dihydro-N,N,2-trimethyl-5-oxo-6H-pyrrolo[3,4-b]pyridine-6-acetamide
CAS 1174538-59-0C19H18Cl3N3O2
1,1-Dimethylethyl N-[4-(2,4-dichlorophenyl)-6-[2-(dimethylamino)-2-oxoethyl]-6,7-dihydro-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-3-yl]-N-methylcarbamate chemical structure, C24H28Cl2N4O4, CAS 1177408-89-7
1,1-Dimethylethyl N-[4-(2,4-dichlorophenyl)-6-[2-(dimethylamino)-2-oxoethyl]-6,7-dihydro-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridin-3-yl]-N-methylcarbamate
CAS 1177408-89-7C24H28Cl2N4O4
4-(2,4-Dichlorophenyl)-6-[2-(dimethylamino)-2-oxoethyl]-6,7-dihydro-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridine-3-carboxylic acid chemical structure, C19H17Cl2N3O4, CAS 1185263-74-4
4-(2,4-Dichlorophenyl)-6-[2-(dimethylamino)-2-oxoethyl]-6,7-dihydro-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridine-3-carboxylic acid
CAS 1185263-74-4C19H17Cl2N3O4
4-(2,4-Dichlorophenyl)-6-[(dimethylamino)carbonyl]-6,7-dihydro-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridine-3-carbonyl chloride chemical structure, C18H14Cl3N3O3, CAS 1184832-14-1
4-(2,4-Dichlorophenyl)-6-[(dimethylamino)carbonyl]-6,7-dihydro-2-methyl-5-oxo-5H-pyrrolo[3,4-b]pyridine-3-carbonyl chloride
CAS 1184832-14-1C18H14Cl3N3O3