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Murcko scaffold

Ring system with 3 rings and 15 atoms

52 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
15
Chemicals
52
With full pages
6
Scaffold SMILES

c1nc(N2CCCCC2)c2ccsc2n1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold c1nc(N2CCCCC2)c2ccsc2n1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 48 of 52 chemicals

5,6-Dimethyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine chemical structure, C13H17N3S, CAS 303065-98-7
5,6-Dimethyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine
CAS 303065-98-7C13H17N3S
5,6-Dimethyl-4-(4-methyl-1-piperidinyl)thieno[2,3-d]pyrimidine chemical structure, C14H19N3S, CAS 302952-38-1
5,6-Dimethyl-4-(4-methyl-1-piperidinyl)thieno[2,3-d]pyrimidine
CAS 302952-38-1C14H19N3S
1-(6-Methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid chemical structure, C13H15N3O2S, CAS 831242-24-1
1-(6-Methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid
CAS 831242-24-1C13H15N3O2S
1-(5,6-Dimethyl-thieno[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid chemical structure, C14H17N3O2S, CAS 842971-60-2
1-(5,6-Dimethyl-thieno[2,3-d]pyrimidin-4-yl)-piperidine-4-carboxylic acid
CAS 842971-60-2C14H17N3O2S
1-(6-Ethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid chemical structure, C14H17N3O2S, CAS 842971-64-6
1-(6-Ethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid
CAS 842971-64-6C14H17N3O2S
Methyl 2-amino-4-piperidinothieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C13H16N4O2S, CAS 866020-42-0
Methyl 2-amino-4-piperidinothieno[2,3-d]pyrimidine-6-carboxylate
CAS 866020-42-0C13H16N4O2S
1-(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C14H18N4OS, CAS 785705-53-5
1-(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CAS 785705-53-5C14H18N4OS
1-(6-Methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C13H16N4OS, CAS 434915-49-8
1-(6-Methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CAS 434915-49-8C13H16N4OS
4-(4-Methylpiperidin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C12H15N3S, CAS 379241-43-7
4-(4-Methylpiperidin-1-yl)thieno[2,3-d]pyrimidine
CAS 379241-43-7C12H15N3S
Ethyl 1-(5-methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C15H19N3O2S, CAS 681428-55-7
Ethyl 1-(5-methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylate
CAS 681428-55-7C15H19N3O2S
6-Ethyl-4-piperidin-1-yl-thieno[2,3-d]pyrimidine chemical structure, C13H18ClN3S, CAS 5251-80-9
6-Ethyl-4-piperidin-1-yl-thieno[2,3-d]pyrimidine
CAS 5251-80-9C13H18ClN3S
5,6-Dimethyl-4-(3-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine chemical structure, C14H19N3S, CAS 422561-50-0
5,6-Dimethyl-4-(3-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine
CAS 422561-50-0C14H19N3S
1-(Thieno[2,3-d]pyrimidin-4-yl)piperidine-3-carboxylic acid chemical structure, C12H13N3O2S, CAS 771509-89-8
1-(Thieno[2,3-d]pyrimidin-4-yl)piperidine-3-carboxylic acid
CAS 771509-89-8C12H13N3O2S
2,5-Dimethyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C14H17N3O2S, CAS 441720-70-3
2,5-Dimethyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 441720-70-3C14H17N3O2S
Ethyl 5-methyl-4-(3-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C16H21N3O2S, CAS 422560-83-6
Ethyl 5-methyl-4-(3-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylate
CAS 422560-83-6C16H21N3O2S
Ethyl 5-methyl-4-(2-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylate chemical structure, C16H21N3O2S, CAS 421565-57-3
Ethyl 5-methyl-4-(2-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylate
CAS 421565-57-3C16H21N3O2S
6-Ethyl-2-methyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine chemical structure, C14H19N3S, CAS 879766-58-2
6-Ethyl-2-methyl-4-piperidin-1-ylthieno[2,3-d]pyrimidine
CAS 879766-58-2C14H19N3S
1-(6-Ethyl-2-methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide chemical structure, C15H20N4OS, CAS 876887-20-6
1-(6-Ethyl-2-methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxamide
CAS 876887-20-6C15H20N4OS
1-(6-Ethyl-2-methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid chemical structure, C15H19N3O2S, CAS 876887-16-0
1-(6-Ethyl-2-methylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylic acid
CAS 876887-16-0C15H19N3O2S
Methyl 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylate chemical structure, C15H19N3O2S, CAS 1389574-25-7
Methyl 1-(5,6-dimethylthieno[2,3-d]pyrimidin-4-yl)piperidine-4-carboxylate
CAS 1389574-25-7C15H19N3O2S
1-(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ol chemical structure, C13H17N3OS, CAS 923706-97-2
1-(5,6-Dimethylthieno[2,3-d]pyrimidin-4-yl)piperidin-4-ol
CAS 923706-97-2C13H17N3OS
1-Thieno[2,3-d]pyrimidin-4-yl-piperidin-4-ol chemical structure, C11H13N3OS, CAS 916610-28-1
1-Thieno[2,3-d]pyrimidin-4-yl-piperidin-4-ol
CAS 916610-28-1C11H13N3OS
2-Methyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine oxalate chemical structure, C14H17N3O4S, CAS 381731-72-2
2-Methyl-4-(piperidin-1-yl)thieno[2,3-d]pyrimidine oxalate
CAS 381731-72-2C14H17N3O4S
5-Methyl-4-(4-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylic acid chemical structure, C14H17N3O2S, CAS 421562-52-9
5-Methyl-4-(4-methylpiperidin-1-yl)thieno[2,3-d]pyrimidine-6-carboxylic acid
CAS 421562-52-9C14H17N3O2S