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Murcko scaffold

Ring system with 2 rings and 11 atoms

8 chemicals on CompoundList share this ring system.

Rings
2
Scaffold atoms
11
Chemicals
8
With full pages
5
Scaffold SMILES

O=C1CCCC2=C1CC=CN2

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CCCC2=C1CC=CN2

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

4,7,7-Trimethyl-2-methylsulfanyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carbonitrile chemical structure, C14H18N2OS, CAS 221217-57-8
4,7,7-Trimethyl-2-methylsulfanyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carbonitrile
CAS 221217-57-8C14H18N2OS
4-Butyl-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile chemical structure, C17H24N2O, CAS 860611-69-4
4-Butyl-2,7,7-trimethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile
CAS 860611-69-4C17H24N2O
2,4,7,7-Tetramethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile chemical structure, C14H18N2O, CAS 19732-58-2
2,4,7,7-Tetramethyl-5-oxo-1,4,5,6,7,8-hexahydro-3-quinolinecarbonitrile
CAS 19732-58-2C14H18N2O
4-Ethyl-7,7-dimethyl-2-methylsulfanyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carbonitrile chemical structure, C15H20N2OS, CAS 201424-83-1
4-Ethyl-7,7-dimethyl-2-methylsulfanyl-5-oxo-1,4,6,8-tetrahydroquinoline-3-carbonitrile
CAS 201424-83-1C15H20N2OS
2-Ethylsulfanyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile chemical structure, C16H22N2OS, CAS 252351-66-9
2-Ethylsulfanyl-4-(2-methylpropyl)-5-oxo-4,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile
CAS 252351-66-9C16H22N2OS
3,4-Quinolinedicarboxylic acid, 1,4,5,6,7,8-hexahydro-5-oxo-, diethyl ester chemical structure, C15H19NO5, CAS 131929-07-2
3,4-Quinolinedicarboxylic acid, 1,4,5,6,7,8-hexahydro-5-oxo-, diethyl ester
CAS 131929-07-2C15H19NO5
3,4-Quinolinedicarboxylic acid, 1,4,5,6,7,8-hexahydro-7,7-dimethyl-5-oxo-, diethyl ester chemical structure, C17H23NO5, CAS 131929-08-3
3,4-Quinolinedicarboxylic acid, 1,4,5,6,7,8-hexahydro-7,7-dimethyl-5-oxo-, diethyl ester
CAS 131929-08-3C17H23NO5
2-(Cyanomethylsulfanyl)-7,7-dimethyl-5-oxo-4-propan-2-yl-1,4,6,8-tetrahydroquinoline-3-carbonitrile chemical structure, C17H21N3OS, CAS 201424-77-3
2-(Cyanomethylsulfanyl)-7,7-dimethyl-5-oxo-4-propan-2-yl-1,4,6,8-tetrahydroquinoline-3-carbonitrile
CAS 201424-77-3C17H21N3OS