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Murcko scaffold

Ring system with 3 rings and 18 atoms

30 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
18
Chemicals
30
With full pages
1
Scaffold SMILES

O=C1CC2CC(OC(=O)c3ccccc3)CC2O1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C1CC2CC(OC(=O)c3ccccc3)CC2O1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 30 of 30 chemicals

(3aR,4S,5R,6aS)-5-(Benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one chemical structure, C15H16O5, CAS 39746-00-4
(3aR,4S,5R,6aS)-5-(Benzoyloxy)hexahydro-4-(hydroxymethyl)-2H-cyclopenta[b]furan-2-one
CAS 39746-00-4C15H16O5
4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C15H16O5, CAS 172821-93-1
4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 172821-93-1C15H16O5
5-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-4-(3-oxo-1-octenyl)-2H-cyclopenta(b)furan-2-one chemical structure, C22H26O5, CAS 40834-86-4
5-(Benzoyloxy)-3,3a,4,5,6,6a-hexahydro-4-(3-oxo-1-octenyl)-2H-cyclopenta(b)furan-2-one
CAS 40834-86-4C22H26O5
(3aR,4R,5R,6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C15H16O5, CAS 2218532-66-0
(3aR,4R,5R,6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 2218532-66-0C15H16O5
(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C15H14O5, CAS 39746-01-5
(3aR,4R,5R,6aS)-4-Formyl-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 39746-01-5C15H14O5
(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxyoct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C22H28O5, CAS 40834-88-6
(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxyoct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 40834-88-6C22H28O5
[(3aR,4R,5R,6aS)-4-[(E,3S)-3-[tert-Butyl(dimethyl)silyl]oxyoct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate chemical structure, C28H42O5Si
[(3aR,4R,5R,6aS)-4-[(E,3S)-3-[tert-Butyl(dimethyl)silyl]oxyoct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate
C28H42O5Si
(3aR,4R,5R,6aS)-2-Oxo-4-((E)-3-oxooct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C22H26O5, CAS 185225-06-3
(3aR,4R,5R,6aS)-2-Oxo-4-((E)-3-oxooct-1-en-1-yl)hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 185225-06-3C22H26O5
[4-[(E)-3-Hydroxy-3-methyloct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate chemical structure, C23H30O5
[4-[(E)-3-Hydroxy-3-methyloct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate
C23H30O5
(3AS,4R,5S,6aR)-4-(hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C15H16O5, CAS 53275-53-9
(3AS,4R,5S,6aR)-4-(hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 53275-53-9C15H16O5
Tafluprost impurity 23 chemical structure, C15H16O5, CAS 3062053-57-7
Tafluprost impurity 23
CAS 3062053-57-7C15H16O5
(3AR,4R,5R,6aS)-5-(benzoyloxy)hexahydro-4-(3-oxo-1-octen-1-yl)-2H-cyclopenta[b]furan-2-one chemical structure, C22H26O5
(3AR,4R,5R,6aS)-5-(benzoyloxy)hexahydro-4-(3-oxo-1-octen-1-yl)-2H-cyclopenta[b]furan-2-one
C22H26O5
(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxyoct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C22H28O5
(3aR,4R,5R,6aS)-4-((S,E)-3-Hydroxyoct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
C22H28O5
(3aR,4R,5R,6aS)-4-[(1Z,3S)-3-Hydroxy-3-methyloct-1-en-1-yl]-2-oxo-hexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C23H30O5
(3aR,4R,5R,6aS)-4-[(1Z,3S)-3-Hydroxy-3-methyloct-1-en-1-yl]-2-oxo-hexahydro-2H-cyclopenta[b]furan-5-yl benzoate
C23H30O5
(3aR,4R,5R,6aS)-4-((E)-4,4-Difluoro-3-oxooct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C22H24F2O5, CAS 50889-48-0
(3aR,4R,5R,6aS)-4-((E)-4,4-Difluoro-3-oxooct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 50889-48-0C22H24F2O5
(3aR,4R,5R,6aS)-4-(4,4-Difluoro-3-oxooct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C22H24F2O5
(3aR,4R,5R,6aS)-4-(4,4-Difluoro-3-oxooct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
C22H24F2O5
2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)hexahydro-4-(3-hydroxy-3-Methyl-1-octenyl)-, [3aR-[3aa,4a(1E,3S*),5b,6aa]]- chemical structure, C23H30O5
2H-Cyclopenta[b]furan-2-one, 5-(benzoyloxy)hexahydro-4-(3-hydroxy-3-Methyl-1-octenyl)-, [3aR-[3aa,4a(1E,3S*),5b,6aa]]-
C23H30O5
(3AR,4R,5R,6AS)-4-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C23H30O5, CAS 54142-12-0
(3AR,4R,5R,6AS)-4-((S,E)-3-hydroxy-3-methyloct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 54142-12-0C23H30O5
(3aR,4R,5R,6aS)-4-((S,E)-3-((tert-Butyldimethylsilyl)oxy)oct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C28H42O5Si, CAS 587869-81-6
(3aR,4R,5R,6aS)-4-((S,E)-3-((tert-Butyldimethylsilyl)oxy)oct-1-en-1-yl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 587869-81-6C28H42O5Si
[4-(3-Hydroxyoct-1-enyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate chemical structure, C22H28O5
[4-(3-Hydroxyoct-1-enyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate
C22H28O5
[4-(4,4-Difluoro-3-oxooct-1-enyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate chemical structure, C22H24F2O5
[4-(4,4-Difluoro-3-oxooct-1-enyl)-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate
C22H24F2O5
[4-[3-[tert-Butyl(dimethyl)silyl]oxyoct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate chemical structure, C28H42O5Si
[4-[3-[tert-Butyl(dimethyl)silyl]oxyoct-1-enyl]-2-oxo-3,3a,4,5,6,6a-hexahydrocyclopenta[b]furan-5-yl] benzoate
C28H42O5Si
rel-(3aR,4S,5R,6aS)-5-(Benzoyloxy)-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-2H-cyclopenta[b]furan-2-one chemical structure, C21H30O5Si, CAS 81203-77-2
rel-(3aR,4S,5R,6aS)-5-(Benzoyloxy)-4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]hexahydro-2H-cyclopenta[b]furan-2-one
CAS 81203-77-2C21H30O5Si
rel-(3aR,4S,5R,6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate chemical structure, C15H16O5, CAS 81244-64-6
rel-(3aR,4S,5R,6aS)-4-(Hydroxymethyl)-2-oxohexahydro-2H-cyclopenta[b]furan-5-yl benzoate
CAS 81244-64-6C15H16O5