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Murcko scaffold

Ring system with 3 rings and 17 atoms

8 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
17
Chemicals
8
With full pages
1
Scaffold SMILES

O=C(Nc1cc2c(s1)CCC2)C1CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=C(Nc1cc2c(s1)CCC2)C1CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 8 of 8 chemicals

Ethyl 2-[(cyclohexylcarbonyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate chemical structure, C17H23NO3S, CAS 315712-39-1
Ethyl 2-[(cyclohexylcarbonyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylate
CAS 315712-39-1C17H23NO3S
2-Cyclohexaneamido-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylic acid chemical structure, C15H19NO3S, CAS 790263-42-2
2-Cyclohexaneamido-4H,5H,6H-cyclopenta[b]thiophene-3-carboxylic acid
CAS 790263-42-2C15H19NO3S
Dimethyl 2-[(cyclohexylcarbonyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylate chemical structure, C18H23NO5S, CAS 308299-19-6
Dimethyl 2-[(cyclohexylcarbonyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3,4-dicarboxylate
CAS 308299-19-6C18H23NO5S
2-{[3-(Ethoxycarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]carbamoyl}cyclohexanecarboxylic acid chemical structure, C18H23NO5S, CAS 353770-28-2
2-{[3-(Ethoxycarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]carbamoyl}cyclohexanecarboxylic acid
CAS 353770-28-2C18H23NO5S
2-{[3-(Propoxycarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]carbamoyl}cyclohexanecarboxylic acid chemical structure, C19H25NO5S, CAS 445015-58-7
2-{[3-(Propoxycarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl]carbamoyl}cyclohexanecarboxylic acid
CAS 445015-58-7C19H25NO5S
2-((3-(Methoxycarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)carbamoyl)cyclohexanecarboxylic acid chemical structure, C17H21NO5S, CAS 352700-13-1
2-((3-(Methoxycarbonyl)-5,6-dihydro-4H-cyclopenta[b]thiophen-2-yl)carbamoyl)cyclohexanecarboxylic acid
CAS 352700-13-1C17H21NO5S
2-(Cyclohexanecarboxamido)-N-methyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C16H22N2O2S, CAS 893095-54-0
2-(Cyclohexanecarboxamido)-N-methyl-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 893095-54-0C16H22N2O2S
2-{[(4-Propylcyclohexyl)carbonyl]amino}-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide chemical structure, C18H26N2O2S, CAS 1363980-57-7
2-{[(4-Propylcyclohexyl)carbonyl]amino}-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide
CAS 1363980-57-7C18H26N2O2S