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Murcko scaffold

Ring system with 3 rings and 21 atoms

13 chemicals on CompoundList share this ring system.

Rings
3
Scaffold atoms
21
Chemicals
13
With full pages
2
Scaffold SMILES

O=S(=O)(c1ccccc1)C1(c2ccccc2)CCCCC1

A Bemis-Murcko scaffold is what remains of a molecule when every side chain is removed: the rings and the chains that link them. Chemicals that share a scaffold often belong to the same compound series, which helps when you look for analogues, alternative suppliers or related building blocks.

Substructure search with this scaffold
Murcko scaffold O=S(=O)(c1ccccc1)C1(c2ccccc2)CCCCC1

Computed from the structures of the chemicals listed here. Stereo and charges are removed before the scaffold is taken.

Chemicals with this scaffold

Open one to see its structure, properties and suppliers.

Showing 1 to 13 of 13 chemicals

Mk-0752 chemical structure, C21H21ClF2O4S, CAS 471905-41-6
Mk-0752
CAS 471905-41-6C21H21ClF2O4S
2-((1s,4s)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)acetonitrile chemical structure, C20H18ClF2NO2S, CAS 471905-01-8
2-((1s,4s)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)acetonitrile
CAS 471905-01-8C20H18ClF2NO2S
Mrk-560 chemical structure, C19H17ClF5NO4S2, CAS 677772-84-8
Mrk-560
CAS 677772-84-8C19H17ClF5NO4S2
2-((1s,4s)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)acetaldehyde chemical structure, C20H19ClF2O3S, CAS 656810-85-4
2-((1s,4s)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)acetaldehyde
CAS 656810-85-4C20H19ClF2O3S
2-(4-((4-Chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)ethanol chemical structure, C20H21ClF2O3S, CAS 1426290-03-0
2-(4-((4-Chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)ethanol
CAS 1426290-03-0C20H21ClF2O3S
3-((1s,4r)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanal chemical structure, C21H21ClF2O3S, CAS 656810-86-5
3-((1s,4r)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propanal
CAS 656810-86-5C21H21ClF2O3S
4-((4-Chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexanamine chemical structure, C18H18ClF2NO2S, CAS 471903-58-9
4-((4-Chlorophenyl)sulfonyl)-4-(2,5-difluorophenyl)cyclohexanamine
CAS 471903-58-9C18H18ClF2NO2S
MK-0752 sodium chemical structure, C21H20ClF2NaO4S, CAS 656810-87-6
MK-0752 sodium
CAS 656810-87-6C21H20ClF2NaO4S
1,4-Difluoro-2-(1-(phenylsulfonyl)cyclohexyl)benzene chemical structure, C18H18F2O2S, CAS 471903-54-5
1,4-Difluoro-2-(1-(phenylsulfonyl)cyclohexyl)benzene
CAS 471903-54-5C18H18F2O2S
Orb1701534 chemical structure, C21H21ClF2NaO4S
Orb1701534
C21H21ClF2NaO4S
4-((1s,4r)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)butanenitrile chemical structure, C22H22ClF2NO2S, CAS 656810-88-7
4-((1s,4r)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)butanenitrile
CAS 656810-88-7C22H22ClF2NO2S
3-((1s,4r)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propan-1-ol chemical structure, C21H23ClF2O3S, CAS 471905-69-8
3-((1s,4r)-4-(4-Chlorophenylsulfonyl)-4-(2,5-difluorophenyl)cyclohexyl)propan-1-ol
CAS 471905-69-8C21H23ClF2O3S
C21H23ClF2NaO4S chemical structure, C21H23ClF2NaO4S
C21H23ClF2NaO4S
C21H23ClF2NaO4S